Search Results - "Parsons, Sean A"

Vav1 Is Essential for Mechanotactic Crawling and Migration of Neutrophils out of the Inflamed Microvasculature by Phillipson, Mia, Heit, Bryan, Parsons, Sean A, Petri, Bjorn, Mullaly, Sarah C, Colarusso, Pina, Gower, R. Michael, Neely, Gregory, Simon, Scott I, Kubes, Paul

“…Mac-1-dependent crawling is a new step in the leukocyte recruitment cascade that follows LFA-1-dependent adhesion and precedes emigration. Neutrophil adhesion…”
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The role of CD14 in neutrophil recruitment within the liver microcirculation during endotoxemia by McAvoy, Erin F, McDonald, Braedon, Parsons, Sean A, Wong, Connie H, Landmann, Regine, Kubes, Paul

“…During Gram-negative sepsis and endotoxemia, CD14 is essential for the recognition of LPS by the TLR4 complex and subsequent generation of systemic…”
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The Fps/Fes kinase regulates the inflammatory response to endotoxin through down-regulation of TLR4, NF-κB activation, and TNF-α secretion in macrophages by Parsons, Sean A., Greer, Peter A.

“…Fps/Fes and Fer are members of a distinct subfamily of cytoplasmic protein tyrosine kinases that have recently been implicated in the regulation of innate…”
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Fps/Fes kinase regulates leucocyte recruitment and extravasation during inflammation by Parsons, Sean A, Mewburn, Jeffrey D, Truesdell, Peter, Greer, Peter A

“…Fps/Fes and Fer comprise a distinct subfamily of cytoplasmic protein-tyrosine kinases, and have both been implicated in the regulation of innate immunity…”
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Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo by Petri, Björn, Kaur, Jaswinder, Long, Elizabeth M., Li, Hang, Parsons, Sean A., Butz, Stefan, Phillipson, Mia, Vestweber, Dietmar, Patel, Kamala D., Robbins, Stephen M., Kubes, Paul

“…The endothelium actively participates in neutrophil migration out of the vasculature via dynamic, cytoskeleton-dependent rearrangements leading to the…”
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Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment by Krohn, Regina M, Parsons, Sean A, Fichna, Jakub, Patel, Kamala D, Yates, Robin M, Sharkey, Keith A, Storr, Martin A

“…Non-psychotropic atypical cannabinoids have therapeutic potential in a variety of inflammatory conditions including those of the gastrointestinal tract. Here…”
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Endothelial paxillin and focal adhesion kinase (FAK) play a critical role in neutrophil transmigration by Parsons, Sean A., Sharma, Ritu, Roccamatisi, Dawn L., Zhang, Hong, Petri, Björn, Kubes, Paul, Colarusso, Pina, Patel, Kamala D.

“…During an inflammatory response, endothelial cells undergo morphological changes to allow for the passage of neutrophils from the blood vessel to the site of…”
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Studying leukocyte recruitment under flow conditions by Parsons, Sean A, Jurzinsky, Christophe, Cuvelier, Susan L, Patel, Kamala D

“…Leukocyte recruitment from the vasculature occurs under conditions of haemodynamic shear stress. The parallel plate flow chamber apparatus is an in vitro…”
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Genetic disruption of the growth hormone receptor does not influence motoneuron survival in the developing mouse by Parsons, Sean A, Banks, Glen B, Rowland, Jenny A, Coschigano, Karen T, Kopchick, John J, Waters, Michael J, Noakes, Peter G

“…In the rodent central nervous system (CNS) during the five days prior to birth, both growth hormone (GH) and its receptor (GHR) undergo transient increases in…”
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Transgenic mice overexpressing an endothelial‐targeted Fas‐inducing apoptosis construct exhibit pulmonary hypertension associated with marked lung arterial remodeling by Goldthorpe, Heather, Parsons, Sean A., Jiang, Jin-Yi, Deng, Yupu, Stewart, Duncan J.

“…Abstract only Objective Pulmonary arterial hypertension (PAH) is a lethal disease, characterized by complex vascular lesions and increased pulmonary vascular…”
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The Fps/Fes kinase regulates the inflammatory response to endotoxin through down-regulation of TLR4, NF-kappaB activation, and TNF-alpha secretion in macrophages by Parsons, Sean A, Greer, Peter A

“…Fps/Fes and Fer are members of a distinct subfamily of cytoplasmic protein tyrosine kinases that have recently been implicated in the regulation of innate…”
Get full text