Search Results - "Parry, Renate"

STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability by Ranoa, Diana Rose E, Widau, Ryan C, Mallon, Stephen, Parekh, Akash D, Nicolae, Claudia M, Huang, Xiaona, Bolt, Michael J, Arina, Ainhoa, Parry, Renate, Kron, Stephen J, Moldovan, George-Lucian, Khodarev, Nikolai N, Weichselbaum, Ralph R

“…Given the integral role of stimulator of interferon genes (STING, ) in the innate immune response, its loss or impairment in cancer is thought to primarily…”
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Preliminary Study of the Effect of Stereotactic Body Radiotherapy (SBRT) on the Immune System in Lung Cancer Patients Unfit for Surgery: Immunophenotyping Analysis by Navarro-Martín, Arturo, Galiana, Isabel Linares, Berenguer Frances, Miguel A, Cacicedo, Jon, Cañas Cortés, Rut, Comas Anton, Silvia, Padrones Sánchez, Susana, Bolívar Cuevas, Santiago, Parry, Renate, Guedea Edo, Ferran

“…An immunophenotyping analysis was performed in peripheral blood samples from seven patients with lung cancer unfit for surgery treated with stereotactic body…”
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Attenuation of the DNA Damage Response by Transforming Growth Factor-Beta Inhibitors Enhances Radiation Sensitivity of Non–Small-Cell Lung Cancer Cells In Vitro and In Vivo by Du, Shisuo, MD, PhD, Bouquet, Sophie, PhD, Lo, Chen-Hao, MS, Pellicciotta, Ilenia, PhD, Bolourchi, Shiva, MS, Parry, Renate, PhD, Barcellos-Hoff, Mary Helen, PhD

“…Purpose To determine whether transforming growth factor (TGF)-β inhibition increases the response to radiation therapy in human and mouse non–small-cell lung…”
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Identification of a novel prostate tumor target, Mindin/RG-1, for antibody-based radiotherapy of prostate cancer by PARRY, Renate, SCHNEIDER, Doug, BIROC, Sandra, KRETSCHMER, Peter J, HALKS-MILLER, Meredith, KLOCKER, Helmut, YING ZHU, LARSEN, Brent, COBB, Ronald R, BRINGMANN, Peter, ROTH, Georg, LEWIS, Jason S, HUDSON, Debra, DINTER, Harald, PARRY, Gordon, PARKES, Debbie, XUAN, Jian-Ai, NEWTON, Alicia, TOY, Pam, LIN, Rick, HARKINS, Rick, ALICKE, Bruno

“…Gene expression analysis showed that a human mindin homologue, mindin/RG-1, is expressed selectively in prostate tissues and that its expression level is…”
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In Vivo Biodistribution, PET Imaging, and Tumor Accumulation of 86Y- and 111In-Antimindin/RG-1, Engineered Antibody Fragments in LNCaP Tumor-Bearing Nude Mice by Schneider, Douglas W, Heitner, Tara, Alicke, Bruno, Light, David R, McLean, Kirk, Satozawa, Noboru, Parry, Gordon, Yoo, Jeongsoo, Lewis, Jason S, Parry, Renate

“…To optimize in vivo tissue uptake kinetics and clearance of engineered monoclonal antibody (mAb) fragments for radiotherapeutic and radiodiagnostic…”
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Correlation of radiosensitivity of lung carcinoma to CD137L endogenous expression levels by Girdhani, Swati, Rodriguez, Andrew, Dua, Rajiv, Parry, Renate

“…Abstract only e14229 Background: Radiation therapy is a cornerstone in the management of cancer. Preclinical and clinical evidence indicate the therapeutic…”
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Autocrine TGFβ Is a Survival Factor for Monocytes and Drives Immunosuppressive Lineage Commitment by Gonzalez-Junca, Alba, Driscoll, Kyla E, Pellicciotta, Ilenia, Du, Shisuo, Lo, Chen Hao, Roy, Ritu, Parry, Renate, Tenvooren, Iliana, Marquez, Diana M, Spitzer, Matthew H, Barcellos-Hoff, Mary Helen

“…Transforming growth factor β (TGFβ) is an effector of immune suppression and contributes to a permissive tumor microenvironment that compromises effective…”
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Poly (ADP-ribose) polymerase inhibitor, an effective radiosensitizer in lung and pancreatic cancers by Hastak, Kedar, Bhutra, Steven, Parry, Renate, Ford, James M

“…The development of stereotactic body radiation therapy (SBRT) has revolutionized radiation therapy for lung cancers and is an emerging treatment option for…”
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IMMU-12. TGFβ ACTIVATION BY RADIATION OPPOSES IMMUNE REJECTION OF INTRACRANIAL GL261 by Barcellos-Hoff, Mary, Gonzalez-Junca, Alba, Vera, Denis Beckford, VanBrocklin, Henry, Franc, Benjamin, Parry, Renate

“…Abstract Enabling anti-tumor immunity in brain is a challenge due to its unique microenvironment that includes tissue-specific extracellular matrix, immune…”
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Abstract LB-280: FLASH: A novel paradigm changing tumor irradiation platform that enhances therapeutic ratio by reducing normal tissue toxicity and activating immune pathways by Girdhani, Swati, Abel, Eric, Katsis, Alexander, Rodriquez, Andrew, Senapati, Shilpa, KuVillanueva, Angel, Jackson, Isabel L., Eley, John, Vujaskovic, Zeljko, Parry, Renate

“…Abstract Summary: A novel irradiation platform using a proton beam leads to an improved therapeutic window through sparing of normal tissue toxicity…”
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Abstract 3599: Implementation of a fully automated 3D foci counting algorithm to determine DNA damage in cells by Katsis, Alexander, Abel, Eric, Pavlyuchkova, Raisa, Senapati, Shilpa, Girdhani, Swati, Parry, Renate

“…Abstract Background: The number of DNA double stand breaks (DSBs) induced after ionizing radiation is strongly correlated with cell death, mutation and cancer…”
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Abstract 5490: Poly (ADP-ribose) polymerase inhibitor LT-626 sensitizes lung and pancreatic cancers to fractionated radiation therapy by Hastak, Kedar, McPherson, Lisa, Shen, Yuqiao, Parry, Renate, Ford, James M.

“…Abstract The development of stereotactic body radiation therapy (SBRT) has revolutionized radiation therapy for lung cancers and is an emerging treatment…”
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Abstract 5715: Modulation of Radiation Response after TGFβ signaling Blockade in Non-small Cell Lung Cancer (NSCLC) Cell Carcinomas by Du, Shisuo, Bouquet, Fanny, Pellicciotta, Ilenia, Parry, Renate, Barcellos-Hoff, Mary Helen

“…Abstract Lung cancer remains one of the most prevalent and deadliest malignancies worldwide. Radiotherapy (RT) is a major therapeutic modality for inoperable…”
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Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture by XUAN, Jian-Ai, SCHNEIDER, Doug, LIGHT, David, PARRY, Renate, POLOKOFF, Mark, WHITLOW, Marc, QINGYU WU, PARRY, Gordon, TOY, Pam, LIN, Rick, NEWTON, Alicia, YING ZHU, FINSTER, Silke, VOGEL, David, MINTZER, Bob, DINTER, Harald

“…Hepsin is a type II transmembrane serine protease that is expressed in normal liver, and at lower levels in kidney, pancreas, and testis. Several studies have…”
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In Vivo Biodistribution, PET Imaging, and Tumor Accumulation of 86 Y- and 111 In-Antimindin/RG-1, Engineered Antibody Fragments in LNCaP Tumor–Bearing Nude Mice by Schneider, Douglas W., Heitner, Tara, Alicke, Bruno, Light, David R., McLean, Kirk, Satozawa, Noboru, Parry, Gordon, Yoo, Jeongsoo, Lewis, Jason S., Parry, Renate

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In Vivo Biodistribution, PET Imaging, and Tumor Accumulation of ^sup 86^Y- and ^sup 111^In-Antimindin/RG-1, Engineered Antibody Fragments in LNCaP Tumor-Bearing Nude Mice by Schneider, Douglas W, Heitner, Tara, Alicke, Bruno, Light, David R, McLean, Kirk, Satozawa, Noboru, Parry, Gordon, Yoo, Jeongsoo, Lewis, Jason S, Parry, Renate

“…To optimize in vivo tissue uptake kinetics and clearance of engineered monoclonal antibody (mAb) fragments for radiotherapeutic and radiodiagnostic…”
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Targeting tomoregulin for radioimmunotherapy of prostate cancer by ZHAO, Xiao-Yan, SCHNEIDER, Doug, MÜLLER-TIEMANN, Beate, PARRY, Gordon, DINTER, Harald, BIROC, Sandra L, PARRY, Renate, ALICKE, Bruno, TOY, Pamela, XUAN, Jian-Ai, SAKAMOTO, Choitsu, WADA, Ken, SCHULZE, Michael

“…Radiotherapy is an effective approach for the treatment of local prostate cancer. However, once prostate cancer metastasizes, radiotherapy cannot be used due…”
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