Search Results - "Parry, David A D"
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Localisation of keratin K78 in the basal layer and first suprabasal layers of stratified epithelia completes expression catalogue of type II keratins and provides new insights into sequential keratin expression
Published in Cell and tissue research (01-03-2016)“…Among the 26 human type II keratins, K78 is the only one that has not yet been explored with regard to its expression characteristics. Here, we show that, at…”
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50 Years of the steric-blocking mechanism in vertebrate skeletal muscle: a retrospective
Published in Journal of muscle research and cell motility (01-09-2023)“…Fifty years have now passed since Parry and Squire proposed a detailed structural model that explained how tropomyosin, mediated by troponin, played a…”
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3
An experimental model of contusion injury in humans
Published in PloS one (17-11-2022)“…Contusion injuries are common in sport, but our knowledge of the responses to injury primarily come from animal studies and research using eccentric exercise…”
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New consensus nomenclature for mammalian keratins
Published in The Journal of cell biology (17-07-2006)“…Keratins are intermediate filament-forming proteins that provide mechanical support and fulfill a variety of additional functions in epithelial cells. In 1982,…”
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The Amino-Terminal Region of Drosophila MSL1 Contains Basic, Glycine-Rich, and Leucine Zipper-Like Motifs That Promote X Chromosome Binding, Self-Association, and MSL2 Binding, Respectively
Published in Molecular and Cellular Biology (01-10-2005)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Microtubule actin crosslinking factor 1b: a novel plakin that localizes to the Golgi complex
Published in Journal of cell science (15-08-2005)“…MACF1 (microtubule actin crosslinking factor), also called ACF7 (actin crosslinking family 7) is a cytoskeletal linker protein that can associate with both…”
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Structure and topology of the linkers in the conserved lepidosaur β-keratin chain with four 34-residue repeats support an interfilament role for the central linker
Published in Journal of structural biology (01-10-2020)“…•The 20 topologies of the four 34-residue repeats and the three linkers are described.•A serine-X dipeptide repeat occurs in the central linker only.•A…”
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Consequences of Two Different Amino-Acid Substitutions at the Same Codon in KRT14 Indicate Definitive Roles of Structural Distortion in Epidermolysis Bullosa Simplex Pathogenesis
Published in Journal of investigative dermatology (01-09-2011)“…Numerous inherited diseases develop due to missense mutations, leading to an amino-acid substitution. Whether an amino-acid change is pathogenic depends on the…”
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Keratin intermediate filament chains in the European common wall lizard (Podarcis muralis) and a potential keratin filament crosslinker
Published in Journal of structural biology (01-12-2021)“…•Sequences of 28 Type I and II KIF chains in common wall lizard.•Type I and II genes lie in clusters on chromosomes 13 and 2 respectively.•Heads and tails of…”
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Keratin intermediate filament chains in tuatara (Sphenodon punctatus): A comparison of tuatara and human sequences
Published in Journal of structural biology (01-03-2021)“…•The sequences of 25 Type I and Type II keratin intermediate filament chains from tuatara are reported.•The head and tail sequences in human and tuatara show…”
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Cingulin and paracingulin tether myosins-2 to junctions to mechanoregulate the plasma membrane
Published in The Journal of cell biology (03-07-2023)“…The mechanisms that regulate the spatial sorting of nonmuscle myosins-2 (NM2) isoforms and couple them mechanically to the plasma membrane are unclear. Here we…”
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Potential implications of the glycosylation patterns in collagen α1(I) and α2(I) chains for fibril assembly and growth
Published in Journal of structural biology (01-03-2023)“…[Display omitted] •Post-translational modifications of collagen from four animals are identified.•Nine new hydroxylysine glycosylation sites identified in…”
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The structural basis of the filament-matrix texture in the avian/reptilian group of hard β-keratins
Published in Journal of structural biology (01-02-2011)“…Avian hard keratin has a filament-matrix texture in which the filaments contain a helical array of twisted β-sheets and the matrix has unusually high…”
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Fifty years of coiled-coils and α-helical bundles: A close relationship between sequence and structure
Published in Journal of structural biology (01-09-2008)“…α-Helical coiled coils are remarkable for the diversity of related conformations that they adopt in both fibrous and globular proteins, and for the range of…”
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Lepidosaur ß-keratin chains with four 34-residue repeats: Modelling reveals a potential filament-crosslinking role
Published in Journal of structural biology (01-01-2020)“…•The four 34-residue repeat chains may have repeats in different filaments thereby crosslinking them together.•This would endow the epidermal appendage with…”
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Structures of the ß-Keratin Filaments and Keratin Intermediate Filaments in the Epidermal Appendages of Birds and Reptiles (Sauropsids)
Published in Genes (17-04-2021)“…The epidermal appendages of birds and reptiles (the sauropsids) include claws, scales, and feathers. Each has specialized physical properties that facilitate…”
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Promiscuous Dimerization Between the Caenorhabditis elegans IF Proteins and a Hypothesis to Explain How Multiple IFs Persist Over Evolutionary Time
Published in Journal of molecular evolution (01-09-2019)“…Our previous calculations of ionic interactions indicated that the Caenorhabditis elegans intermediate filament (IF) IFA proteins, in addition to IFA/IFB-1…”
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Amino acid sequence homologies in the hard keratins of birds and reptiles, and their implications for molecular structure and physical properties
Published in Journal of structural biology (01-12-2014)“…Avian and reptilian epidermal appendages such as feathers, claws and scales exhibit a filament–matrix texture. Previous studies have established that both…”
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Intermediate filament structure in fully differentiated (oxidised) trichocyte keratin
Published in Journal of structural biology (01-10-2017)“…For the past 50years there has been considerable debate over the sub-structure of the fully differentiated (oxidised) trichocyte keratin intermediate filament…”
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Molecular structure of sauropsid β-keratins from tuatara (Sphenodon punctatus)
Published in Journal of structural biology (01-07-2019)“…•Although the molecular structure of β-keratins from the Archosaurs (birds, crocodiles), testudines (turtles) and squamates (lizards and snakes) has been…”
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