Search Results - "Parrish, Mark L."

Regulation of Gene Expression by Lithium and Depletion of Inositol in Slices of Adult Rat Cortex by Brandish, Philip E., Su, Ming, Holder, Daniel J., Hodor, Paul, Szumiloski, John, Kleinhanz, Robert R., Forbes, Jaime E., McWhorter, Mollie E., Duenwald, Sven J., Parrish, Mark L., Na, Sang, Liu, Yuan, Phillips, Robert L., Renger, John J., Sankaranarayanan, Sethu, Simon, Adam J., Scolnick, Edward M.

“…Lithium inhibits inositol monophosphatase at therapeutically effective concentrations, and it has been hypothesized that depletion of brain inositol levels is…”
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Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing by Castle, John, Garrett-Engele, Phil, Armour, Christopher D, Duenwald, Sven J, Loerch, Patrick M, Meyer, Michael R, Schadt, Eric E, Stoughton, Roland, Parrish, Mark L, Shoemaker, Daniel D, Johnson, Jason M

“…Microarrays offer a high-resolution means for monitoring pre-mRNA splicing on a genomic scale. We have developed a novel, unbiased amplification protocol that…”
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cDNA targets improve whole blood gene expression profiling and enhance detection of pharmocodynamic biomarkers: a quantitative platform analysis by Parrish, Mark L, Wright, Chris, Rivers, Yarek, Argilla, David, Collins, Heather, Leeson, Brendan, Loboda, Andrey, Nebozhyn, Michael, Marton, Matthew J, Lejnine, Serguei

“…Genome-wide gene expression profiling of whole blood is an attractive method for discovery of biomarkers due to its non-invasiveness, simple clinical site…”
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Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease by Dobrin, Radu, Zhu, Jun, Molony, Cliona, Argman, Carmen, Parrish, Mark L, Carlson, Sonia, Allan, Mark F, Pomp, Daniel, Schadt, Eric E

“…Obesity is a particularly complex disease that at least partially involves genetic and environmental perturbations to gene-networks connecting the hypothalamus…”
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Endoplasmic Reticulum-Associated Degradation Is Required for Cold Adaptation and Regulation of Sterol Biosynthesis in the Yeast Saccharomyces cerevisiae by Loertscher, Jennifer, Larson, Lynnelle L, Matson, Clinton K, Parrish, Mark L, Felthauser, Alicia, Sturm, Aaron, Tachibana, Christine, Bard, Martin, Wright, Robin

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Differential Associations of Circulating MicroRNAs With Pathogenic Factors in NAFLD by Ezaz, Ghideon, Trivedi, Hirsh D., Connelly, Margery A., Filozof, Claudia, Howard, Kellie, L.Parrish, Mark, Kim, Misung, Herman, Mark A., Nasser, Imad, Afdhal, Nezam H., Jiang, Z. Gordon, Lai, Michelle

“…Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous disease driven by genetic and environmental factors. MicroRNAs (miRNAs) serve as pleiotropic…”
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Parallel analysis of tagged deletion mutants efficiently identifies genes involved in endoplasmic reticulum biogenesis by Wright, Robin, Parrish, Mark L., Cadera, Emily, Larson, Lynnelle, Matson, Clinton K., Garrett‐Engele, Philip, Armour, Chris, Lum, Pek Yee, Shoemaker, Daniel D.

“…Increased levels of HMG‐CoA reductase induce cell type‐ and isozyme‐specific proliferation of the endoplasmic reticulum. In yeast, the ER proliferations…”
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Mutations That Affect Vacuole Biogenesis Inhibit Proliferation of the Endoplasmic Reticulum in Saccharomyces cerevisiae by Koning, Ann J, Larson, Lynnelle L, Cadera, Emily J, Parrish, Mark L, Wright, Robin L

“…In yeast, increased levels of the sterol biosynthetic enzyme, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase isozyme, Hmg1p, induce assembly of…”
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A microarray platform comparison for neuroscience applications by Parrish, Mark L, Wei, Nan, Duenwald, Sven, Tokiwa, George Y, Wang, Yanqun, Holder, Daniel, Dai, Hongyue, Zhang, Xiaohua, Wright, Christopher, Hodor, Paul, Cavet, Guy, Phillips, Robert L, Sun, Benjamin I, Fare, Thomas L

“…To address the need for high sensitivity in gene expression profiling of small neural tissue samples (∼100 ng total RNA), we compared a novel RT-PCR-IVT…”
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Proliferation of the endoplasmic reticulum occurs normally in cells that lack a functional unfolded protein response by Larson, Lynnelle L., Parrish, Mark L., Koning, Ann J., Wright, Robin L.

“…Increased expression of certain ER membrane proteins leads to biogenesis of novel ER membrane arrays. These structures provide models in which to explore the…”
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A 42-kilodalton annexin-like protein is associated with plant vacuoles by Seals, Darren F., Mark L. Parrish, Randall, Stephen K.

“…A 42-kD, calcium-dependent, membrane-binding protein (VCaB42) was associated with partially purified vacuole membranes. Membrane-dissociation assays indicated…”
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Identification of the sequences in HMG-CoA reductase required for karmellae assembly by Parrish, M L, Sengstag, C, Rine, J D, Wright, R L

“…In all eukaryotic cells that have been examined, specific membrane arrays are induced in response to increased levels of the ER membrane protein, HMG-CoA…”
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