Search Results - "Parrish, Jonathan"

[3+2] Photooxygenation of aryl cyclopropanes via visible light photocatalysis by Lu, Zhan, Parrish, Jonathan D., Yoon, Tehshik P.

“…We report that Ru(bpz)32+ is an excellent sensitizer for the photooxygenation of aryl cyclopropanes upon irradiation with visible light. The effectiveness of…”
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Endoperoxide Synthesis by Photocatalytic Aerobic [2 + 2 + 2] Cycloadditions by Parrish, Jonathan D, Ischay, Michael A, Lu, Zhan, Guo, Song, Peters, Noël R, Yoon, Tehshik P

“…Structurally novel endoperoxides can be sythesized by the photocatalytic cyclotrimerization of bis(styrene) substrates with molecular oxygen. The optimal…”
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Enantioselective Total Synthesis of Brevetoxin A: Unified Strategy for the B, E, G, and J Subunits by Crimmins, Michael T., Ellis, J. Michael, Emmitte, Kyle A., Haile, Pamela A., McDougall, Patrick J., Parrish, Jonathan D., Zuccarello, J. Lucas

“…Brevetoxin A is a decacyclic ladder toxin that possesses 5‐, 6‐, 7‐, 8‐, and 9‐membered oxacycles, as well as 22 tetrahedral stereocenters. Herein, we describe…”
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[3+2] Photooxygenation of aryl cylopropanes via visible light photocatalysis by Lu, Zhan, Parrish, Jonathan D, Yoon, Tehshik P

“…We report that Ru(bpz) is an excellent sensitizer for the photooxygenation of aryl cyclopropanes upon irradiation with visible light. The effectiveness of this…”
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Total Synthesis of Brevetoxin A by Crimmins, Michael T, Zuccarello, J. Lucas, Ellis, J. Michael, McDougall, Patrick J, Haile, Pamela A, Parrish, Jonathan D, Emmitte, Kyle A

“…A total synthesis of brevetoxin A is reported. Two tetracyclic coupling partners, prepared from previously reported advanced fragments, were effectively united…”
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Novel 2,3,4,5-tetrahydro-benzo[d]azepine derivatives of 2,4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse models by Mesaros, Eugen F., Burke, Jason P., Parrish, Jonathan D., Dugan, Benjamin J., Anzalone, Andrew V., Angeles, Thelma S., Albom, Mark S., Aimone, Lisa D., Quail, Matthew R., Wan, Weihua, Lu, Lihui, Huang, Zeqi, Ator, Mark A., Ruggeri, Bruce A., Cheng, Mangeng, Ott, Gregory R., Dorsey, Bruce D.

“…The synthesis and biological evaluation of potent and selective anaplastic lymphoma kinase (ALK) inhibitors from a novel class of 2,4-diaminopyrimidines,…”
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Lowering the Entropic Barrier for Binding Conformationally Flexible Inhibitors to Enzymes by Khan, Amir R, Parrish, Jonathan C, Fraser, Marie E, Smith, Whitney W, Bartlett, Paul A, James, Michael N. G

“…The design of inhibitors with enhanced potency against proteolytic enzymes has many applications for the treatment of human diseases. In addition to the…”
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Convergent, Stereoselective Synthesis of the GHIJ Fragment of Brevetoxin A by Crimmins, Michael T, Zuccarello, J. Lucas, Cleary, Pamela A, Parrish, Jonathan D

“…A stereoselective synthesis of the GHIJ fragment of brevetoxin A utilizing a convergent assembly strategy is described. Glycolate alkylation, ring-closing…”
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Abstract 4139170: Relationship between hemodynamics and oxygen consumption in hypertrophic cardiomyopathy during maximal stress testing by Parrish, Jonathan, Blain, Alasdair, Okwose, Nduka, Fuller, Amy, Alyahya, Alaa, Russell, Sophie, Eggett, Christopher, Luke, Peter, Bailey, Kristian, MacGowan, Guy, Jakovljevic, Djordje, Charman, Sarah

“…Abstract only Background: Hypertrophic cardiomyopathy (HCM) is a global heart disease with great variability in disease severity, which can lead to significant…”
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Synthesis and Evaluation of Keto-Glutamine Analogues as Potent Inhibitors of Severe Acute Respiratory Syndrome 3CLpro by Jain, Rajendra P, Pettersson, Hanna I, Zhang, Jianmin, Aull, Katherine D, Fortin, Pascal D, Huitema, Carly, Eltis, Lindsay D, Parrish, Jonathan C, James, Michael N. G, Wishart, David S, Vederas, John C

“…The 3C-like proteinase (3CLpro) of severe acute respiratory syndrome (SARS) coronavirus is a key target for structure-based drug design against this viral…”
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Mental health screening and referral to treatment in dental practices: A scoping review by Culmer, Nathan P, Smith, Todd Brenton, Berryhill, M Blake, Gurenlian, JoAnn, Simpson, Lance, Ogden, Shawnna, Parrish, Jonathan, Ryan, Lacey, White, Nicole, Bettis, Merrill, Greenwood, Charlotte

“…The purpose of this study was to conduct a scoping review to examine and summarize the characteristics of research related to mental health (MH) screenings…”
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A tale of two charges: distinct roles for an acidic and a basic amino acid in the structure and function of cytochrome c by Parrish, J C, Guillemette, J G, Wallace, C J

“…Cytochrome c is a small electron transport protein found in the intermembrane space of mitochondria. As it interacts with a number of different physiological…”
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Structural studies of conformationally-restricted ligands binding to aspartic peptidases by James, Michael N. G., Fraser, Marie E., Khan, Amir R., Parrish, Jonathan C., Smith, Whitney W., Bartlett, Paul A.

“…Abstract only…”
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The pedagogy of technology: Attitudes of biochemistry students towards practice questions in online game or pdf format by Milner, Rachel Elizabeth, Wright, Adrienne, Parrish, Jonathan, Keenan, Louann, Gnarpe, Judy

“…Abstract only In our biochemistry course we provide multiple choice questions in PDF format. Recently, we decided to use an online game. To explore possible…”
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(E)-1-(2'-Deoxy-β-d-ribofuranosyl)-2,4-difluoro-5-(2-iodovinyl)benzene by MARK, Brian L, PARRISH, Jonathan C, WANG, Zhi-Xian, WIEBE, Leonard I, KNAUS, Edward E, JAMES, Michael N. G

“…This analysis of the title compound, C13H13F2IO3, establishes the orientation of (E)-5-(CH=CH-I) as antiperiplanar (ap) to the C-C bond (5-6 position) of the…”
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Research and Teaching: Exploring the Use of an Online Quiz Game to Provide Formative Feedback in a Large-Enrollment, Introductory Biochemistry Course by Milner, Rachel, Parrish, Jonathan, Wright, Adrienne, Gnarpe, Judy, Keenan, Louanne

“…In a large-enrollment, introductory biochemistry course for nonmajors, the authors provide students with formative feedback through practice questions in PDF…”
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Exploring the Use of an Online Quiz Game to Provide Formative Feedback in a Large-Enrollment, Introductory Biochemistry Course by Milner, Rachel, Parrish, Jonathan, Wright, Adrienne, Gnarpe, Judy, Keenan, Louanne

“…In our large-enrollment, introductory biochemistry course for nonmajors, we provide students with formative feedback through practice questions in PDF format…”
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Definition of a Nucleotide Binding Site on Cytochrome c by Photoaffinity Labeling by McIntosh, David B., Parrish, Jonathan C., Wallace, Carmichael J.A.

“…We have used TNP-8N3-AMP (2′(3′)-O-(2,4,6-trinitrophenyl)-8-azidoadenosine monophosphate) and TNP-8N3-ATP to probe the ATP binding site(s) of cytochrome c…”
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Synergy in Protein Engineering by Woods, Anthony C., Guillemette, J. Guy, Parrish, Jonathan C., Smith, Michael, Wallace, CarmichaelJ. A.

“…Semisynthesis is a chemical technique of protein engineering that provides a valuable complement to directed mutagenesis. It is the method of choice when the…”
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Corrigendum to “Novel 2,3,4,5-tetrahydro-benzo[ d]azepine derivatives of 2,4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse models” [Bioorg. Med. Chem. Lett. 21 (2011) 463] by Mesaros, Eugen F., Burke, Jason P., Parrish, Jonathan D., Dugan, Benjamin J., Anzalone, Andrew V., Angeles, Thelma S., Albom, Mark S., Aimone, Lisa D., Quail, Matthew R., Wan, Weihua, Lu, Lihui, Huang, Zeqi, Ator, Mark A., Ruggeri, Bruce A., Cheng, Mangeng, Ott, Gregory R., Dorsey, Bruce D.

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