Search Results - "Parrinello, Nunziatina L"

TLR4 signaling drives mesenchymal stromal cells commitment to promote tumor microenvironment transformation in multiple myeloma by Giallongo, Cesarina, Tibullo, Daniele, Camiolo, Giuseppina, Parrinello, Nunziatina L., Romano, Alessandra, Puglisi, Fabrizio, Barbato, Alessandro, Conticello, Concetta, Lupo, Gabriella, Anfuso, Carmelina Daniela, Lazzarino, Giacomo, Li Volti, Giovanni, Palumbo, Giuseppe Alberto, Di Raimondo, Francesco

“…Inflammation represents a key feature and hallmark of tumor microenvironment playing a major role in the interaction with mesenchymal stromal cells (MSC) in…”
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α-Lipoic Acid Reduces Iron-induced Toxicity and Oxidative Stress in a Model of Iron Overload by Camiolo, Giuseppina, Tibullo, Daniele, Giallongo, Cesarina, Romano, Alessandra, Parrinello, Nunziatina L, Musumeci, Giuseppe, Di Rosa, Michelino, Vicario, Nunzio, Brundo, Maria V, Amenta, Francesco, Ferrante, Margherita, Copat, Chiara, Avola, Roberto, Li Volti, Giovanni, Salvaggio, Antonio, Di Raimondo, Francesco, Palumbo, Giuseppe A

“…Iron toxicity is associated with organ injury and has been reported in various clinical conditions, such as hemochromatosis, thalassemia major, and…”
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Iron regulates myeloma cell/macrophage interaction and drives resistance to bortezomib by Camiolo, Giuseppina, Barbato, Alessandro, Giallongo, Cesarina, Vicario, Nunzio, Romano, Alessandra, Parrinello, Nunziatina L., Parenti, Rosalba, Sandoval, Joaquín Cantón, García-Moreno, Diana, Lazzarino, Giacomo, Avola, Roberto, Palumbo, Giuseppe A., Mulero, Victoriano, Li Volti, Giovanni, Tibullo, Daniele, Di Raimondo, Francesco

“…Iron plays a major role in multiple processes involved in cell homeostasis such as metabolism, respiration and DNA synthesis. Cancer cells exhibit pronounced…”
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Antiproliferative and Antiangiogenic Effects of Punica granatum Juice (PGJ) in Multiple Myeloma (MM) by Tibullo, Daniele, Caporarello, Nunzia, Giallongo, Cesarina, Anfuso, Carmelina Daniela, Genovese, Claudia, Arlotta, Carmen, Puglisi, Fabrizio, Parrinello, Nunziatina L, Bramanti, Vincenzo, Romano, Alessandra, Lupo, Gabriella, Toscano, Valeria, Avola, Roberto, Brundo, Maria Violetta, Di Raimondo, Francesco, Raccuia, Salvatore Antonio

“…Multiple myeloma (MM) is a clonal B-cell malignancy characterized by an accumulation of clonal plasma cells (PC) in the bone marrow (BM) leading to bone…”
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Proteomic Analysis Reveals Autophagy as Pro-Survival Pathway Elicited by Long-Term Exposure with 5-Azacitidine in High-Risk Myelodysplasia by Romano, Alessandra, Giallongo, Cesarina, La Cava, Piera, Parrinello, Nunziatina L, Chiechi, Antonella, Vetro, Calogero, Tibullo, Daniele, Di Raimondo, Francesco, Liotta, Lance A, Espina, Virginia, Palumbo, Giuseppe A

“…Azacytidine (5-AZA) is the standard first-choice treatment for high-risk myelodysplasia (MDS) patients. However, the clinical outcome for those patients who…”
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Bortezomib modulates CHIT1 and YKL40 in monocyte-derived osteoclast and in myeloma cells by Tibullo, Daniele, Di Rosa, Michelino, Giallongo, Cesarina, La Cava, Piera, Parrinello, Nunziatina L, Romano, Alessandra, Conticello, Concetta, Brundo, Maria V, Saccone, Salvatore, Malaguarnera, Lucia, Di Raimondo, Francesco

“…Osteolytic bone disease is a common manifestation of multiple myeloma (MM) that leads to progressive skeleton destruction and is the most severe cause of…”
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Clinical Impact of the Immunome in Lymphoid Malignancies: The Role of Myeloid-Derived Suppressor Cells by Vetro, Calogero, Romano, Alessandra, Ancora, Flavia, Coppolino, Francesco, Brundo, Maria V, Raccuia, Salvatore A, Puglisi, Fabrizio, Tibullo, Daniele, La Cava, Piera, Giallongo, Cesarina, Parrinello, Nunziatina L

“…The better definition of the mutual sustainment between neoplastic cells and immune system has been translated from the bench to the bedside acquiring value as…”
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Granulocyte-like myeloid derived suppressor cells (G-MDSC) are increased in multiple myeloma and are driven by dysfunctional mesenchymal stem cells (MSC) by Giallongo, Cesarina, Tibullo, Daniele, Parrinello, Nunziatina L, La Cava, Piera, Di Rosa, Michelino, Bramanti, Vincenzo, Di Raimondo, Cosimo, Conticello, Concetta, Chiarenza, Annalisa, Palumbo, Giuseppe A, Avola, Roberto, Romano, Alessandra, Di Raimondo, Francesco

“…Granulocytic-Myeloid-derived suppressor cells (G-MDSC) are increased in Multiple Myeloma (MM) patients but the mechanisms of G-MDSC generation are still…”
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Immune off‐target effects of Brentuximab Vedotin in relapsed/refractory Hodgkin Lymphoma by Romano, Alessandra, Parrinello, Nunziatina L., Chiarenza, Annalisa, Motta, Giovanna, Tibullo, Daniele, Giallongo, Cesarina, La Cava, Piera, Camiolo, Giuseppina, Puglisi, Fabrizio, Palumbo, Giuseppe A., Di Raimondo, Francesco

“…Summary Hodgkin Lymphoma (HL) is associated with deep microenvironment re‐shaping and myeloid dysfunction. Given that only limited data are available regarding…”
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Monocytic myeloid‐derived suppressor cells as prognostic factor in chronic myeloid leukaemia patients treated with dasatinib by Giallongo, Cesarina, Parrinello, Nunziatina L., La Cava, Piera, Camiolo, Giuseppina, Romano, Alessandra, Scalia, Marina, Stagno, Fabio, Palumbo, Giuseppe A., Avola, Roberto, Li Volti, Giovanni, Tibullo, Daniele, Di Raimondo, Francesco

“…Myeloid suppressor cells are a heterogeneous group of myeloid cells that are increased in patients with chronic myeloid leukaemia (CML) inducing T cell…”
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Correction: TLR4 signaling drives mesenchymal stromal cells commitment to promote tumor microenvironment transformation in multiple myeloma by Giallongo, Cesarina, Tibullo, Daniele, Camiolo, Giuseppina, Parrinello, Nunziatina L., Romano, Alessandra, Puglisi, Fabrizio, Barbato, Alessandro, Conticello, Concetta, Lupo, Gabriella, Anfuso, Carmelina Daniela, Lazzarino, Giacomo, Volti, Giovanni Li, Palumbo, Giuseppe Alberto, Di Raimono, Francesco

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Plasmocytosis and Immunoparesis but Not Neutrophil to Lymphocyte Ratio Can Predict Time to Treatment in Smoldering Myeloma by Romano, Alessandra, Consoli, Marzia L, Parisi, Marina, Cavalli, Maide, Parrinello, Nunziatina L, Conticello, Concetta, Di Raimondo, Francesco

“…Objectives: We recently identified the ratio between absolute neutrophils count and absolute lymphocyte count, NLR ≥2, as a predictor of progression free…”
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Contribution of High-Density Neutrophils to Multiple Myeloma Microenvironment Dysregulation by Romano, Alessandra, Giallongo, Cesarina, Parrinello, Nunziatina L, Tibullo, Daniele, Puglisi, Fabrizio, Camiolo, Giusy, La Cava, Piera, Parisi, Marina, Consoli, maria Letizia, Conticello, Concetta, Di Raimondo, Francesco, Luca, Vanella

“…Background and objective: Multiple Myeloma (MM) is a plasma cell malignancy with a well documented immune dysfunction. Previous reports in murine models and…”
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Mesenchymal STEM CELLS Favor Tumor Growth By Generating Granulocyte-like Myeloid Derived Suppressor CELLS in CML Patients by Giallongo, Cesarina, Parrinello, Nunziatina L, Tibullo, Daniele, Bellofiore, Claudia, La Cava, Piera, Romano, Alessandra, Chiarenza, Annalisa, Stagno, Fabio, Vigneri, Paolo, Palumbo, Giuseppe A., Di Raimondo, Francesco

“…INTRODUCTION. The complex interplay between cancer cells and immune system allows neoplastic cells to evade immune surveillance and expand. Recently, our and…”
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Monocytic Myeloid Derived Suppressor CELLS (M-MDSC) As Prognostic Factor in Chronic Myeloid Leukemia Patients Treated with Dasatinib by Giallongo, Cesarina, Parrinello, Nunziatina L, Tibullo, Daniele, La Cava, Piera, Romano, Alessandra, Chiarenza, Annalisa, Stagno, Fabio, Vigneri, Paolo, Palumbo, Giuseppe A, Di Raimondo, Francesco, Bellofiore, Claudia

“…INTRODUCTION. Myeloid suppressor cells are a heterogeneous group of myeloid cells that are increased in most cancer patients. Recently, we and another group…”
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Arginase 1 Is a Marker of Myeloid-Mediated Immunosuppression with Prognostic Meaning in Classic Hodgkin Lymphoma by Romano, Alessandra, Parrinello, Nunziatina L, Tibullo, Daniele, Vetro, Calogero, Giallongo, Cesarina, La Cava, Piera, Chiarenza, Annalisa, Villari, Loredana, Tripodo, Claudio, Motta, Giovanna, Caruso, Laura, Gallamini, Andrea, Pileri, Stefano A, Di Raimondo, Francesco

“…Purpose: Neutrophilia is hallmark of classic Hodgkin Lymphoma (cHL), but its precise characterization remains elusive. We aimed at investigating the…”
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Immune Suppression By High-Density Neutrophils Predicts Short Progression-Free Survival in Multiple Myeloma by Romano, Alessandra, Manteiga, Jose, Simeon, Vittorio, Parrinello, Nunziatina L, Giallongo, Cesarina, La Cava, Piera, Conticello, Concetta, Tibullo, Daniele, Fontana, Francesca, Ciceri, Fabio, Cremasco, Floriana, Fabbri, Monica, Musto, Pellegrino, Cenci, Simone, Di Raimondo, Francesco

“…Background and Objective: Our previous work showed that neutrophils sedimenting on top of red cells after density gradients, defined as high-density…”
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