Search Results - "Parrilla Castellar, Edgardo R."
-
1
ALK-negative anaplastic large cell lymphoma is a genetically heterogeneous disease with widely disparate clinical outcomes
Published in Blood (28-08-2014)“…Anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma (ALCL) is a CD30-positive T-cell non-Hodgkin lymphoma that morphologically resembles…”
Get full text
Journal Article -
2
Somatic Mutations in LRRK2 Identify a Subset of Invasive Mammary Carcinomas Associated with High Mutation Burden
Published in The American journal of pathology (01-12-2020)“…Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most common cause of familial Parkinson disease. Although LRRK2-related Parkinson disease…”
Get full text
Journal Article -
3
BRAF V600E Expression in Langerhans Cell Histiocytosis: Clinical and Immunohistochemical Study on 25 Pulmonary and 54 Extrapulmonary Cases
Published in The American journal of surgical pathology (01-04-2014)“…Pulmonary Langerhans cell histiocytosis (PLCH) has been postulated to be a smoking-related non-neoplastic condition, distinct from extrapulmonary LCH, which is…”
Get full text
Journal Article -
4
Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels
Published in The American journal of pathology (01-03-2016)“…The transcription factor far upstream element binding protein (FBP) binds and activates the MYC promoter when far upstream element is via TFIIH helicase…”
Get full text
Journal Article -
5
Do Histopathology and Clinical Outcomes of Breast Atypia Vary by Race/Ethnicity?
Published in The Journal of surgical research (01-11-2020)“…The clinical behavior of breast cancer varies by racial and ethnic makeup (REM), but the impact of REM on the clinical outcomes of breast atypia remains…”
Get full text
Journal Article -
6
The Influence of Age on the Histopathology and Prognosis of Atypical Breast Lesions
Published in The Journal of surgical research (01-09-2019)“…Although several prognostic variables and risk factors for breast cancer are age-related, the association between age and risk of cancer with breast atypia is…”
Get full text
Journal Article -
7
Invasive Aspergillosis Due to Neosartorya udagawae
Published in Clinical infectious diseases (01-07-2009)“…Background. Invasive aspergillosis (IA) is most commonly caused by the morphospecies Aspergillus fumigatus. However, genetic-based methods indicate that…”
Get full text
Journal Article -
8
Dial 9–1–1 for DNA damage: the Rad9–Hus1–Rad1 (9–1–1) clamp complex
Published in DNA Repair (01-08-2004)“…Genotoxic stress activates checkpoint signaling pathways that block cell cycle progression, trigger apoptosis, and regulate DNA repair. Studies in yeast and…”
Get full text
Book Review Journal Article -
9
Cut5 Is Required for the Binding of Atr and DNA Polymerase α to Genotoxin-damaged Chromatin
Published in The Journal of biological chemistry (14-11-2003)“…DNA damage triggers the assembly of checkpoint signaling proteins on chromatin that activate the Chk1 signaling pathway and block S-phase progression. Here we…”
Get full text
Journal Article -
10
Evidence-based medicine as a tool for clinical decision-making in Puerto Rico
Published in Puerto Rico health sciences journal (01-06-2008)“…Evidence-based medicine (EBM) is defined as "the process of systematically finding, appraising and using contemporaneous research findings as the basis for…”
Get full text
Journal Article -
11
Abstract 3538: Genetic biomarkers for risk stratification of patients with peripheral T-cell lymphoma
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Background: Peripheral T-cell lymphomas (PTCLs) represent a heterogeneous group of generally aggressive malignancies, with 5-year overall survival…”
Get full text
Journal Article -
12
Cut5 Is Required for the Binding of Atr and DNA Polymerase α to Genotoxin-damaged Chromatin
Published in The Journal of biological chemistry (14-11-2003)“…DNA damage triggers the assembly of checkpoint signaling proteins on chromatin that activate the Chk1 signaling pathway and block S-phase progression. Here we…”
Get full text
Journal Article -
13