Search Results - "Parratt, John D E"

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    Multiple sclerosis: Distribution of inflammatory cells in newly forming lesions by Henderson, Andrew P. D., Barnett, Michael H., Parratt, John D. E., Prineas, John W.

    Published in Annals of neurology (01-12-2009)
    “…Objective CD4 T‐cell–dependent macrophage activation directed against a myelin or oligodendrocyte antigen is generally thought to be the mechanism causing…”
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    Oligodendrocytes and the early multiple sclerosis lesion by Prineas, John W., Parratt, John D. E.

    Published in Annals of neurology (01-07-2012)
    “…There is little agreement among neuropathologists regarding the timing and nature of oligodendrocyte loss in multiple sclerosis (MS). This review describes…”
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    Immunoglobulins and complement in postmortem multiple sclerosis tissue by Barnett, Michael H., Parratt, John D. E., Cho, Eun-Sook, Prineas, John W.

    Published in Annals of neurology (01-01-2009)
    “…Objective To identify evidence of a discrete, specific immune response in multiple sclerosis (MS) by analyzing the distribution of immunoglobulins and…”
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    Neuromyelitis optica: a demyelinating disease characterized by acute destruction and regeneration of perivascular astrocytes by Parratt, John DE, Prineas, John W

    Published in Multiple sclerosis (01-10-2010)
    “…Background: A serum antibody directed against astrocytes is present in a high proportion of patients with neuromyelitis optica (NMO). The pathogenicity of the…”
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    AQP4 Antibody Assay Sensitivity Comparison in the Era of the 2015 Diagnostic Criteria for NMOSD by Prain, Kerri, Woodhall, Mark, Vincent, Angela, Ramanathan, Sudarshini, Barnett, Michael H., Bundell, Christine S., Parratt, John D. E., Silvestrini, Roger A., Bukhari, Wajih, Brilot, Fabienne, Waters, Patrick, Broadley, Simon A.

    Published in Frontiers in neurology (04-10-2019)
    “…We have compared five different assays for antibodies to aquaporin-4 in 181 cases of suspected Neuromyelitis optica spectrum disorders (NMOSD) and 253 controls…”
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    Fibrosis of the Choroid Plexus Filtration Membrane by Prineas, John W., Parratt, John D. E., Kirwan, Paul D.

    “…We report a previously undescribed inflammatory lesion consisting of deposition of activated complement (C3d and C9neo) in association with major…”
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    Case series: Immune checkpoint inhibitor-induced transverse myelitis by Chatterton, Sophie, Xi, Shuo, Jia, Jessica Xi, Krause, Martin, Long, Georgina V, Atkinson, Victoria, Menzies, Alexander M, Fernando, Suran L, Boyle, Thérèse, Kwok, Samuel, Duggins, Andrew, Karikios, Deme, Parratt, John D E

    Published in Frontiers in neurology (21-02-2023)
    “…Increasing implementation of the highly efficacious immune checkpoint inhibitors (ICIs) has raised awareness of their various complications in the form of…”
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    Multiple sclerosis: Serum anti-CNS autoantibodies by Prineas, John W, Parratt, John D.E

    Published in Multiple sclerosis (01-04-2018)
    “…Background: It is uncertain whether there are autoantibodies detectable by indirect immunofluorescence in the serum of patients with multiple sclerosis (MS)…”
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    3229 Seronegative arthritis as a complication of b-cell depleting therapy in multiple sclerosis by Cheung, Emily, Montague, Turlough, Parratt, John DE

    Published in BMJ neurology open (01-08-2024)
    “…BackgroundB-cell depleting monoclonal antibodies are highly effective treatment for multiple sclerosis (MS) but have rarely been associated with seronegative…”
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    3231 Successful treatment of Hashimoto’s encephalopathy with tocilizumab by Montague, Turlough, Cheung, Emily, Boyle, Therese, Fernando, Suran, Parratt, John DE

    Published in BMJ neurology open (01-08-2024)
    “…Background/ObjectivesHashimoto’s encephalopathy is a neuroimmunological disease associated with anti-thyroid antibodies. Cognitive dysfunction and behavioural…”
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    3233 Unilateral relapsing primary angiitis of the central nervous system (UR-PACNS) – expanding the phenotype by Montague, Turlough, Cheung, Emily, Drummond, Jamie, Fontes-Villaba, Ariadna, Fernando, Suran, Parratt, John DE

    Published in BMJ neurology open (01-08-2024)
    “…Background/ObjectivesPrimary angiitis of the central nervous system (PACNS) is a rare disease that often lacks angiographic abnormalities, resulting in…”
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    Multiple Sclerosis: Microglia, Monocytes, and Macrophage-Mediated Demyelination by Prineas, John W, Parratt, John D E

    “…Abstract This study examined the roles of microglia and monocytes in myelin destruction in patients with early multiple sclerosis (MS). Twenty-two cases were…”
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    117 Multiple sclerosis presenting as a rapidly progressive dementia by Gerbis, Natasha, Parratt, John DE

    Published in BMJ neurology open (01-08-2021)
    “…ObjectivesRapidly progressive dementias manifest with cognitive decline that progresses over weeks to months. It is rare for dementia to present early in the…”
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    Multiple sclerosis in Tayside, Scotland: detection of clusters using a spatial scan statistic by Donnan, Peter T, Parratt, John DE, Wilson, Sally V, Forbes, Raeburn B, O'Riordan, Jonathan I, Swingler, Robert J

    Published in Multiple sclerosis (01-08-2005)
    “…Debate continues over the relative importance of genetic factors over infectious agents in the aetiology of multiple sclerosis (MS). Detection of clusters of…”
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    116 Paraneoplastic progressive-supranuclear palsy like brainstem syndrome associated with lung adenocarcinoma by Gerbis, Natasha, Fontes-Villalba, Ariadna, Aouad, Patrick, Fernando, Suran, Parratt, John DE

    Published in BMJ neurology open (01-08-2021)
    “…ObjectivesProgressive supranuclear palsy (PSP) is a neurodegenerative condition characterised by Parkinsonian features, cervical dystonia and ophthalmoparesis…”
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