Search Results - "Parrado, A R"

Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer’s disease with OSBPL6, PTPRG, and PDCL3 by Herold, C, Hooli, B V, Mullin, K, Liu, T, Roehr, J T, Mattheisen, M, Parrado, A R, Bertram, L, Lange, C, Tanzi, R E

“…The genetic basis of Alzheimer's disease (AD) is complex and heterogeneous. Over 200 highly penetrant pathogenic variants in the genes APP , PSEN1 , and PSEN2…”
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Role of common and rare APP DNA sequence variants in Alzheimer disease by Hooli, B V, Mohapatra, G, Mattheisen, M, Parrado, A R, Roehr, J T, Shen, Y, Gusella, J F, Moir, R, Saunders, A J, Lange, C, Tanzi, R E, Bertram, L

“…More than 30 different rare mutations, including copy number variants (CNVs), in the amyloid precursor protein gene (APP) cause early-onset familial Alzheimer…”
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A second kindred linked to DFNA20 (17q25.3) reduces the genetic interval by DeWan, AT, Parrado, AR, Leal, SM

“…A family ascertained in the United States displays significant evidence of linkage to 17q25.3 (maximum two‐point LOD score 6.32). The non‐syndromic…”
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Health-related direct-to-consumer genetic tests: a public health assessment and analysis of practices related to Internet-based tests for risk of thrombosis by Goddard, K A B, Robitaille, J, Dowling, N F, Parrado, A R, Fishman, J, Bradley, L A, Moore, C A, Khoury, M J

“…Recent years have seen increased concern about direct-to-consumer (DTC) genetic testing (i.e., the sale and use of genetic tests without involving a health…”
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The Map Problem: A Comparison of Genetic and Sequence-Based Physical Maps by DeWan, Andrew T., Parrado, Antonio R., Matise, Tara C., Leal, Suzanne M.

“…The genetic order of autosomal genome-scan markers from Marshfield panels 9 and 10 were compared with their physical order, on the basis of the assembled…”
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Kole ot common and rare APP DNA sequence variants in Alzheimer disease by HOOLI, B. V, MOHAPATRA, G, TANZI, R. E, BERTRAM, L, MATTHEISEN, M, PARRADO, A. R, ROEHR, J. T, SHEN, Y, GUSELLA, J. F, MOIR, R, SAUNDERS, A. J, LANGE, C

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Identification of Barrett's Esophagus in Relatives by Endoscopic Screening by Chak, Amitabh, Faulx, Ashley, Kinnard, Margaret, Brock, Wendy, Willis, Joseph, Wiesner, Georgia L, Parrado, Antonio R, Goddard, Katrina A B

“…Familial aggregation of Barrett's esophagus and its associated cancers has been termed familial Barrett's esophagus (FBE). The aim of the study was to…”
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Map error reduction: using genetic and sequence-based physical maps to order closely linked markers by DeWan, Andrew T, Parrado, Antonio R, Matise, Tara C, Leal, Suzanne M

“…The Marshfield comprehensive genetic maps are frequently used for linkage and association studies, however, for some regions of these maps the marker order has…”
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Evidence for HLA-DQA1 locus being associated with abdominal aortic aneurysms in the Belgian population by Ogata, T., Gregoire, L., Goddard, K. A., Tromp, G., Lancaster, W. D., Parrado, A. R., Lu, Q., SakalihasanN, Natzi, Limet, Raymond, MacKean, G. L., Arthur, C., Kuivaniemi, H.

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Linkage analysis of alcoholism-related electrophysiological phenotypes: genome scans with microsatellites compared to single-nucleotide polymorphisms by Bautista, Jocelyn F, Quade, Shannon R E, Parrado, Antonio R, Goddard, Katrina A B

“…P300 amplitude is an electrophysiological quantitative trait that is correlated with both alcoholism and smoking status. Using the Collaborative Study on the…”
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