Search Results - "Parra Bueno, Paula"
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In Vivo Imaging of the Coupling between Neuronal and CREB Activity in the Mouse Brain
Published in Neuron (Cambridge, Mass.) (04-03-2020)“…Sensory experiences cause long-term modifications of neuronal circuits by modulating activity-dependent transcription programs that are vital for regulation of…”
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Long-Distance Integration of Nuclear ERK Signaling Triggered by Activation of a Few Dendritic Spines
Published in Science (American Association for the Advancement of Science) (29-11-2013)“…The late phase of long-term potentiation (LTP) at glutamatergic synapses, which is thought to underlie long-lasting memory, requires gene transcription in the…”
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3
Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor
Published in Neuron (Cambridge, Mass.) (05-04-2017)“…Elucidating temporal windows of signaling activity required for synaptic and behavioral plasticity is crucial for understanding molecular mechanisms underlying…”
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4
Local autocrine plasticity signaling in single dendritic spines by insulin-like growth factors
Published in Science advances (02-08-2023)“…The insulin superfamily of peptides is essential for homeostasis as well as neuronal plasticity, learning, and memory. Here, we show that insulin-like growth…”
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5
Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor
Published in Neuron (Cambridge, Mass.) (03-05-2017)Get full text
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6
RGS14 Restricts Plasticity in Hippocampal CA2 by Limiting Postsynaptic Calcium Signaling
Published in eNeuro (01-05-2018)“…Pyramidal neurons in hippocampal area CA2 are distinct from neighboring CA1 in that they resist synaptic long-term potentiation (LTP) at CA3 Schaffer…”
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CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca2+ Signals during LTP Induction, but Not Maintenance
Published in Neuron (Cambridge, Mass.) (17-05-2017)“…CaMKII plays a critical role in decoding calcium (Ca2+) signals to initiate long-lasting synaptic plasticity. However, the properties of CaMKII that mediate…”
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8
PKCα integrates spatiotemporally distinct Ca2+ and autocrine BDNF signaling to facilitate synaptic plasticity
Published in Nature neuroscience (01-08-2018)“…The protein kinase C (PKC) enzymes have long been established as critical for synaptic plasticity. However, it is unknown whether Ca 2+ -dependent PKC isozymes…”
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9
Autocrine BDNF–TrkB signalling within a single dendritic spine
Published in Nature (London) (06-10-2016)“…Live fluorescent imaging of murine hippocampal slices shows that NMDAR-dependent glutamate signalling leads to postsynaptic BDNF release, with associated…”
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Dual Regulation of Spine-Specific and Synapse-to-Nucleus Signaling by PKCδ during Plasticity
Published in The Journal of neuroscience (26-07-2023)“…The activity-dependent plasticity of synapses is believed to be the cellular basis of learning. These synaptic changes are mediated through the coordination of…”
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PKC[alpha] integrates spatiotemporally distinct Ca.sup.2+ and autocrine BDNF signaling to facilitate synaptic plasticity
Published in Nature neuroscience (01-08-2018)“…The protein kinase C (PKC) enzymes have long been established as critical for synaptic plasticity. However, it is unknown whether Ca.sup.2+-dependent PKC…”
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12
CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca 2+ Signals during LTP Induction, but Not Maintenance
Published in Neuron (Cambridge, Mass.) (17-05-2017)“…CaMKII plays a critical role in decoding calcium (Ca ) signals to initiate long-lasting synaptic plasticity. However, the properties of CaMKII that mediate Ca…”
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13
Autocrine BDNFTrkB signalling within a single dendritic spine
Published in Nature (London) (06-10-2016)Get full text
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14
ADAP1/Centaurin-α1 Negatively Regulates Dendritic Spine Function and Memory Formation in the Hippocampus
Published in eNeuro (01-01-2021)“…ADAP1/Centaurin-α1 (CentA1) functions as an Arf6 GTPase-activating protein highly enriched in the brain. Previous studies demonstrated the involvement of…”
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15
PKCα integrates spatiotemporally distinct Ca 2+ and autocrine BDNF signaling to facilitate synaptic plasticity
Published in Nature neuroscience (01-08-2018)“…The protein kinase C (PKC) enzymes have long been established as critical for synaptic plasticity. However, it is unknown whether Ca -dependent PKC isozymes…”
Get full text
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