Search Results - "Parr, Naomi M J"
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Primary Focal Segmental Glomerulosclerosis Plasmas Increase Lipid Droplet Formation and Perilipin-2 Expression in Human Podocytes
Published in International journal of molecular sciences (22-12-2022)“…Many patients with primary focal segmental glomerulosclerosis (FSGS) develop recurrence of proteinuria after kidney transplantation. Several circulating…”
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Thrombotic Events in COVID-19 Are Associated With a Lower Use of Prophylactic Anticoagulation Before Hospitalization and Followed by Decreases in Platelet Reactivity
Published in Frontiers in medicine (22-04-2021)“…Coronavirus disease of 2019 (COVID-19) is associated with a prothrombotic state and a high incidence of thrombotic event(s) (TE). To study platelet reactivity…”
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A mutation in the kringle domain of human factor XII that causes autoinflammation, disturbs zymogen quiescence, and accelerates activation
Published in The Journal of biological chemistry (10-01-2020)“…Coagulation factor XII (FXII) drives production of the inflammatory peptide bradykinin. Pathological mutations in the F12 gene, which encodes FXII, provoke…”
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Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation
Published in Blood (07-11-2019)“…The contact system produces the inflammatory peptide bradykinin and contributes to experimental thrombosis. C1 esterase-inhibitor (C1INH) deficiency or…”
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An increase in CD62Ldim neutrophils precedes the development of pulmonary embolisms in COVID‐19 patients
Published in Scandinavian journal of immunology (01-06-2021)“…Objectives A high incidence of pulmonary embolism (PE) is reported in patients with critical coronavirus disease 2019 (COVID‐19). Neutrophils may contribute to…”
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Point-of-care neutrophil CD64 as a rule in diagnostic test for bacterial infections in the emergency department
Published in BMC emergency medicine (14-03-2023)“…Bacterial infections are frequently seen in the emergency department (ED), but can be difficult to distinguish from viral infections and some non-infectious…”
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