New bioactive compounds of the adrenal medullary layer

The review of new data of the studies of the cerebral layers of eight cardioactive peptide and clieopeptide combinations. Research of the physical-chemical and biochemical properties confirm nonidentity of these combinations to the known bioactive peptides of adrenals. The proteins connecting the fa...

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Bibliographic Details
Published in:	Uspekhi fiziologicheskikh nauk Vol. 29; no. 1; p. 3
Main Authors:	Srapionian, R M, Paronian, Z Kh, Saakian, S A
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-01-1998
Subjects:	Adrenal Medulla - secretion Animals Cardiovascular Agents - analysis Cardiovascular Agents - metabolism Cardiovascular Agents - pharmacology Glycopeptides - analysis Glycopeptides - metabolism Glycopeptides - pharmacology Glycopeptides - secretion Peptides - analysis Peptides - metabolism Peptides - pharmacology Peptides - secretion Protein Binding
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Summary:	The review of new data of the studies of the cerebral layers of eight cardioactive peptide and clieopeptide combinations. Research of the physical-chemical and biochemical properties confirm nonidentity of these combinations to the known bioactive peptides of adrenals. The proteins connecting the factors under exploration have also been discovered, suggesting existence of cardioactive protein-peptide complexes in this region. Based on comparison of the studied chemical and biological properties of these combinations with the combinations of hypothalamic cardioactive neurohormones, in particular, with the neurohormone "C", a conclusion was made that combinations of the two regions are structurally and functionally related. The obtained data can be used in practical medicine for prophylactics and treatment of several cardiovascular diseases.
ISSN:	0301-1798