Search Results - "Parolin, Cristina"
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Antiviral activity of cationic amphiphilic drugs
Published in Expert review of anti-infective therapy (04-05-2017)“…Emerging and reemerging viral infections represent a major concern for human and veterinary public health and there is an urgent need for the development of…”
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Ebola Virus Entry: From Molecular Characterization to Drug Discovery
Published in Viruses (19-03-2019)“…Ebola Virus Disease (EVD) is one of the most lethal transmissible infections, characterized by a high fatality rate, and caused by a member of the family. The…”
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3
Molecular Epidemiology of HIV-1 in African Countries: A Comprehensive Overview
Published in Pathogens (Basel) (21-12-2020)“…The human immunodeficiency virus type 1 (HIV-1) originated in non-human primates in West-central Africa and continues to be a major global public health issue,…”
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Human Monocytes Are Suitable Carriers for the Delivery of Oncolytic Herpes Simplex Virus Type 1 In Vitro and in a Chicken Embryo Chorioallantoic Membrane Model of Cancer
Published in International journal of molecular sciences (25-05-2023)“…Oncolytic viruses (OVs) are promising therapeutics for tumors with a poor prognosis. An OV based on herpes simplex virus type 1 (oHSV-1), talimogene…”
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Why Cells and Viruses Cannot Survive without an ESCRT
Published in Cells (Basel, Switzerland) (24-02-2021)“…Intracellular organelles enwrapped in membranes along with a complex network of vesicles trafficking in, out and inside the cellular environment are one of the…”
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Editorial: Novel Insights Into a Functional HIV Cure
Published in Frontiers in microbiology (01-12-2021)Get full text
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Genomic surveillance of SARS-CoV-2 in patients presenting neurological manifestations
Published in PloS one (30-06-2022)“…During the first wave of infections, neurological symptoms in Coronavirus Disease 2019 (COVID-19) patients raised particular concern, suggesting that, in a…”
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Targeting and Understanding HIV Latency: The CRISPR System against the Provirus
Published in Pathogens (Basel) (28-09-2021)“…The presence of latently infected cells and reservoirs in HIV-1 infected patients constitutes a significant obstacle to achieve a definitive cure. Despite the…”
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How to break free: HIV-1 escapes from innovative therapeutic approaches
Published in Frontiers in virology (online) (29-07-2022)“…With nearly 38 million of people worldwide living with HIV-1 and no definitive cure available after almost 40 years of research, AIDS is still a major global…”
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Perspectives on immunotherapy via oncolytic viruses
Published in Infectious agents and cancer (11-02-2019)“…With few exceptions, current chemotherapy and radiotherapy protocols only obtain a slightly prolonged survival with severe adverse effects in patients with…”
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From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors
Published in The journal of microbiology (01-04-2015)“…HIV-1 reverse transcriptase (RT) is still an extremely attractive pharmaceutical target for the identification of new inhibitors possibly active on drug…”
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Persistent and transient olfactory deficits in COVID-19 are associated to inflammation and zinc homeostasis
Published in Frontiers in immunology (14-07-2023)“…The Coronavirus Disease 2019 (COVID-19) is mainly a respiratory syndrome that can affect multiple organ systems, causing a variety of symptoms. Among the most…”
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The Potential Role of Viral Persistence in the Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
Published in Pathogens (Basel) (01-05-2024)“…The infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated not only with the development of acute disease but also with…”
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Molecular Pathology Analysis of SARS-CoV-2 in Syncytiotrophoblast and Hofbauer Cells in Placenta from a Pregnant Woman and Fetus with COVID-19
Published in Pathogens (Basel) (15-04-2021)“…A small number of neonates delivered to women with SARS-CoV-2 infection have been found to become infected through intrauterine transplacental transmission…”
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TaSCA, an Agile Survey on Chemosensory Impairments for Self-Monitoring of COVID-19 Patients: A Pilot Study
Published in Frontiers in neurology (24-02-2021)“…During the COVID-19 pandemic, smell and taste disorders emerged as key non-respiratory symptoms. Due to widespread presence of the disease and to difficult…”
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The ubiquitin-conjugating system: multiple roles in viral replication and infection
Published in Cells (06-05-2014)“…Through the combined action of ubiquitinating and deubiquitinating enzymes, conjugation of ubiquitin to a target protein acts as a reversible…”
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Targeting HIV-1 RNase H: N' -(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants
Published in Viruses (06-07-2020)“…HIV-1 infection requires life-long treatment and with 2.1 million new infections/year, faces the challenge of an increased rate of transmitted drug-resistant…”
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Targeting the Regulatory Subunit R2Alpha of Protein Kinase A in Human Glioblastoma through shRNA-Expressing Lentiviral Vectors
Published in Viruses (13-07-2021)“…Glioblastoma is the most malignant and most common form of brain tumor, still today associated with a poor 14-months median survival from diagnosis. Protein…”
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Feline Tetherin Is Characterized by a Short N-Terminal Region and Is Counteracted by the Feline Immunodeficiency Virus Envelope Glycoprotein
Published in Journal of Virology (01-06-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Simultaneous Expression of Different Therapeutic Genes by Infection with Multiple Oncolytic HSV-1 Vectors
Published in Biomedicines (16-07-2024)“…Oncolytic viruses (OVs) are anti-cancer therapeutics combining the selective killing of cancer cells with the triggering of an anti-tumoral immune response…”
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