Search Results - "Parnitzke, Ulrike"
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Histone deacetylase inhibitor resminostat in combination with sorafenib counteracts platelet-mediated pro-tumoral effects in hepatocellular carcinoma
Published in Scientific reports (05-05-2021)“…In hepatocellular carcinoma (HCC), blood platelets have been linked to tumor growth, epithelial-to-mesenchymal transition (EMT), extrahepatic metastasis and a…”
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Domatinostat favors the immunotherapy response by modulating the tumor immune microenvironment (TIME)
Published in Journal for immunotherapy of cancer (08-11-2019)“…BackgroundThe efficacy of PD-(L)1 blockade depends on the composition of the tumor immune microenvironment (TIME) and is generally higher in tumors with…”
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Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts
Published in Journal of translational medicine (15-01-2018)Get full text
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Resminostat affects transcriptional regulation of disease-related processes in CTCL
Published in European journal of cancer (1990) (01-09-2018)Get full text
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Mode-of-action of HDAC inhibitor resminostat in CTCL
Published in European journal of cancer (1990) (01-10-2021)Get full text
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Abstract 3088: Combination of 4SC-202 and IFN-γ restores mature APC phenotype in AML cells
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Acute myeloid leukemia (AML) is characterized by a differentiation block resulting in accumulation of immature myeloid cells. Differentiation therapy, e.g…”
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Abstract 4722: 4SC-202 increases immunogenicity of tumor cells, induces infiltration of tumor microenvironment with cytotoxic T cells, and primes tumors for combinations with different cancer immunotherapy approaches
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Various histone deacetylases (HDAC) inhibitors were described as beneficially affecting anti-tumoral immune response. Although different HDAC inhibitors were…”
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Resminostat plus sorafenib in hepatocellular carcinoma (HCC) as apotential new treatment approach in platelet-driven solid tumors
Published in Journal of clinical oncology (20-05-2018)“…Abstract only…”
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Abstract 2632: 4SC-202 induces inflamed tumor microenvironment, strongly enhances tumor infiltration with cytotoxic T cells and primes tumors for anti-PD1/PD-L1 therapy
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Various HDAC inhibitors were described as beneficially affecting anti-tumoral immune response. Although different HDAC inhibitors were investigated in…”
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