Search Results - "Parlanti, Luca"

A Versatile and Highly Selective Hypervalent Iodine (III)/2,2,6,6-Tetramethyl-1-piperidinyloxyl-Mediated Oxidation of Alcohols to Carbonyl Compounds by De Mico, Antonella, Margarita, Roberto, Parlanti, Luca, Vescovi, Andrea, Piancatelli, Giovanni

“…Catalytic amounts of 2,2,6,6-tetramethyl-1-piperidinyloxyl (TEMPO) are used in combination with [bis(acetoxy)iodo]benzene (BAIB) as a stoichiometric oxidant in…”
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Hypervalent iodine chemistry: Novel and direct thiocyanation of alkenes using [bis(acetoxy)iodo]benzene/trimethylsilyl isothiocyanate reagent combination. Synthesis of 1,2-dithiocyanates by Bruno, Moira, Margarita, Roberto, Parlanti, Luca, Piancatelli, Giovanni, Trifoni, Maila

“…Novel and direct thiocyanation of alkenes using [bis(acetoxy)iodo]benzene/trimethylsilyl isothiocyanate reagent combination has been developed. A novel and…”
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Total Synthesis and Structural Confirmation of the Marine Natural Product Dysinosin A:  A Novel Inhibitor of Thrombin and Factor VIIa by Hanessian, Stephen, Margarita, Roberto, Hall, Adrian, Johnstone, Shawn, Tremblay, Martin, Parlanti, Luca

“…The structure and absolute configuration of the marine antithrombotic product dysinosin A was confirmed by total synthesis. The strategy involved…”
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Development of a Practical Synthesis of a p38 Kinase Inhibitor via a Safe and Robust Amination by Shi, Zhongping, Kiau, Susanne, Lobben, Paul, Hynes, John, Wu, Hong, Parlanti, Luca, Discordia, Robert, Doubleday, Wendel W, Leftheris, Katerina, Dyckman, Alaric J, Wrobleski, Stephen T, Dambalas, Konstantinos, Tummala, Srinivas, Leung, Simon, Lo, Ehrlic

“…The development of a practical synthesis for a p38 kinase inhibitor is described. The key advances include an improved route to the key intermediate, a…”
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Amination of Heterocyclic Compounds with O-Benzoylhydroxylamine Derivatives by Parlanti, Luca, Discordia, Robert P, Hynes, John, Miller, Michael M, O'Grady, Harold R, Shi, Zhongping

“…The N-amination of heterocyclic compounds 1a−k with O-benzoylhydroxylamine derivatives 5 was developed and demonstrated to be a superior alternative to…”
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Synthesis, Chromatographic Purification, and Isolation of Epothilone–Folic Acid Conjugate BMS-753493 by Kim, Soong-Hoon, de Mas, Nuria, Parlanti, Luca, Lyngberg, Olav K, Ströhlein, Guido, Guo, Zhenrong, Dambalas, Konstantinos, Rosso, Victor W, Yang, Bing-Shiou, Girard, Kevin P, Manaloto, Zerene A, D’Arasmo, Germano, Frigerio, Riccardo E, Wang, Wei, Lu, Xujin, Bolgar, Mark S, Gokhale, Madhushree, Thakur, Ajit B

“…We describe the synthesis, chromatographic purification, and isolation of the epothilone–folic acid conjugate BMS-753493, an investigational new drug candidate…”
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An efficient electrophilic N-amination utilizing in situ generated chloramine under phase transfer conditions by Bhattacharya, Apurba, Patel, Nitin C., Plata, Robert Erik, Peddicord, Michael, Ye, Qingmei, Parlanti, Luca, Palaniswamy, Venkatapuram A., Grosso, John A.

“…An efficient, one-pot, phase transfer N-amination technology was developed. The protocol utilizes chloramine, an inexpensive and safe electrophilic aminating…”
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Asymmetric carbolithiation of 2-phenylselenofumarate derivatives: a short synthesis of (−)-roccellaric acid by Bella, Marco, Margarita, Roberto, Orlando, Claudia, Orsini, Monica, Parlanti, Luca, Piancatelli, Giovanni

“…(−)-Roccellaric acid and variously substituted succinates are obtained through direct asymmetric carbolithiation of 2-phenylselenofumarate derivatives,…”
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Hypervalent Iodine‐Induced Multi‐Component Reactions: Novel Thiocyano‐ and Isothiocyano‐phenylselenenylating Reaction of Alkenes by Margarita, Roberto, Mercanti, Chiara, Parlanti, Luca, Piancatelli, Giovanni

“…A simple and efficient thiocyano‐ or isothiocyano‐phenylselenenylation of alkenes has been developed. The reactions occur when alkenes are treated with…”
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Total synthesis and structural confirmation of the marine natural product dvsinosin A: A novel inhibitor of thrombin and factor VIIa by HANESSIAN, Stephen, MARGARITA, Roberto, HALL, Adrian, JOHNSTONE, Shawn, TREMBLAY, Martin, PARLANTI, Luca

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Reactions of 2,5-dihydro-2,5-dimethoxy-furan with phenylselenenylchloride: Regio- and stereocontrolled generation of highly functionalized C4 building-blocks by D'Onofrio, Franco, Margarita, Roberto, Parlanti, Luca, Pernazza, Daniele, Piancatelli, Giovanni

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New and old challenges in total synthesis. From concept to practice by Hanessian, S., Margarita, Roberto, Hall, Adrian, Johnstone, Shawn, Tremblay, M., Parlanti, L.

“…The total synthesis of dysinosin A, a novel member of the aeruginosin group of marine natural products is discussed. The stereocontrolled synthesis also…”
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Direct amino-phenylselenylation of enoates: An easy route to α-phenylseleno-β-amino esters and β-lactams by Caracciolo Torchiarolo, Giuliano, D'Onofrio, Franco, Margarita, Roberto, Parlanti, Luca, Piancatelli, Giovanni, Bella, Marco

“…A “one-pot” procedure to obtain α-phenylseleno-β-amino esters from the corresponding enoates is described. The target compounds are useful synthetic tools and…”
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The binary reagent PhSeClZnCl 2: a powerful chloro-phenylselenenylating agent of electrophilic olefins by D'Onofrio, Franco, Parlanti, Luca, Piancatelli, Giovanni

“…The binary reagent PhSeClZnCl 2 was found to be powerful for the stereocontrolled conversion of highly electrophilic olefins, such as maleate and fumarate…”
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Hypervalent iodine induced nucleophilic additions to alkenes: Synthesis of 1,2-diperchlorates by De Mico, Antonella, Margarita, Roberto, Parlanti, Luca, Piancatelli, Giovanni, Vescovi, Andrea

“…a novel iodine (III) reagent has been developed by the BAIB/Mg(ClO 4) 2 reagent combination. Reaction of this reagent with alkenes yielded 1,2-diperchlorates…”
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Reactions of 2,5-dihydro-2,5-dimethoxy-furan with phenylselenenylchloride: Regio- and stereocontrolled generation of highly functionalized C 4 building-blocks by D'Onofrio, Franco, Margarita, Roberto, Parlanti, Luca, Pernazza, Daniele, Piancatelli, Giovanni

“…An efficient protocol for stereo- and regiocontrolled synthesis of small polyfunctional molecules is presented. The stereospecific addition of PhSeCl to…”
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Selenium-directed conjugate addition of amines to dimethyl 2-phenylseleno fumarate : Regio and diastereoselective synthesis of 2-phenylseleno-3-amino succinates by Bella, Marco, D'Onofrio, Franco, Margarita, Roberto, Parlanti, Luca, Piancatelli, Giovanni, Mangoni, Alfonso

“…Dimethyl 2-phenylseleno fumarate 1 acts as a strong Michael acceptor of amines, providing the corresponding 2-phenylseleno-3-amino succinates 2a and 2b in very…”
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The binary reagent PhSeClZnCl2: a powerful chloro-phenylselenenylating agent of electrophilic olefins by D'Onofrio, Franco, Parlanti, Luca, Piancatelli, Giovanni

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Hypervalent Iodine-Induced Multi-Component Reactions: Novel Thiocyano- and Isothiocyano-phenylselenenylating Reaction of Alkenes by Margarita, Roberto, Mercanti, Chiara, Parlanti, Luca, Piancatelli, Giovanni

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