Search Results - "Parks, Xiaorong Xu"

The auxiliary subunit KCNE1 regulates KCNQ1 channel response to sustained calcium-dependent PKC activation by Xu Parks, Xiaorong, Qudsi, Haani, Braun, Chen, Lopes, Coeli M B

“…The slow cardiac delayed rectifier current (IKs) is formed by KCNQ1 and KCNE1 subunits and is one of the major repolarizing currents in the heart. Decrease of…”
Get full text

Membrane pools of phosphatidylinositol-4-phosphate regulate KCNQ1/KCNE1 membrane expression by Braun, Chen, Parks, Xiaorong Xu, Qudsi, Haani, Lopes, Coeli M. B.

“…Plasma membrane phosphatidylinositol 4-phosphate (PI4P) is a precursor of PI(4,5)P 2 , an important regulator of a large number of ion channels. Although the…”
Get full text

Stop-codon and C-terminal nonsense mutations are associated with a lower risk of cardiac events in patients with long QT syndrome type 1 by Ruwald, Martin H., MD, PhD, Xu Parks, Xiaorong, PhD, Moss, Arthur J., MD, Zareba, Wojciech, MD, PhD, Baman, Jayson, BS, McNitt, Scott, MS, Kanters, Jorgen K., MD, Shimizu, Wataru, MD, Wilde, Arthur A., MD, PhD, Jons, Christian, MD, PhD, Lopes, Coeli M., PhD

“…Background In long QT syndrome type 1 (LQT1), the location and type of mutations have been shown to affect the clinical outcome. Although haploinsufficiency,…”
Get full text

Statin-specific inhibition of Rab-GTPase regulates cPKC-mediated IKs internalization by Ronzier, Elsa, Parks, Xiaorong Xu, Qudsi, Haani, Lopes, Coeli M.

“…Statins are prescribed for prevention and treatment of coronary artery disease. Statins have different cholesterol lowering abilities, with rosuvastatin and…”
Get full text

Confirming a Role for α9nAChRs and SK Potassium Channels in Type II Hair Cells of the Turtle Posterior Crista by Parks, Xiaorong Xu, Contini, Donatella, Jordan, Paivi M, Holt, Joseph C

“…In turtle posterior cristae, cholinergic vestibular efferent neurons (VENs) synapse on type II hair cells, bouton afferents innervating type II hair cells, and…”
Get full text

Statin Therapy in Long QT Syndrome Type II by Ronzier, Elsa, Xu Parks, Xiaorong, Lopes, Coeli

Get full text

KCNE1 Subunit Phosphorylation Leads to IKs Internalization in Response to Chronic Calcium-Dependent PKC Activation by Ronzier, Elsa, Xu Parks, Xiaorong, Lopes, Coeli M.

Get full text

Fluvastatin inhibits Rab5-mediated IKs internalization caused by chronic Ca2+-dependent PKC activation by Parks, Xiaorong Xu, Ronzier, Elsa, O-Uchi, Jin, Lopes, Coeli M.

“…Statins, in addition to their cholesterol lowering effects, can prevent isoprenylation of Rab GTPase proteins, a key protein family for the regulation of…”
Get full text

PKCβII specifically regulates KCNQ1/KCNE1 channel membrane localization by Braun, Chen, Parks, Xiaorong Xu, Qudsi, Haani, Lopes, Coeli M.

“…The slow voltage-gated potassium channel (IKs) is composed of the KCNQ1 and KCNE1 subunits and is one of the major repolarizing currents in the heart…”
Get full text

DYN-Mediated Internalization of KCNQ1/KCNE1 Channels under Sustained CPKC Activation by Xu Parks, Xiaorong, Ronzier, Elsa, O-Uchi, Jin, Lopes, Coeli M.

Get full text

Statin Inhibits IKs Internalization in Response to Prolonged Stress Stimulus by Parks, Xiaorong Xu, Ronzier, Elsa, Abraham, Rachael E., O-Uchi, Jin, Lopes, Coeli M.

Get full text

Impaired IKs channel activation by Ca2+-dependent PKC shows correlation with emotion/arousal-triggered events in LQT1 by O-Uchi, Jin, Rice, J. Jeremy, Ruwald, Martin H., Parks, Xiaorong Xu, Ronzier, Elsa, Moss, Arthur J., Zareba, Wojciech, Lopes, Coeli M.

“…The most common inherited cardiac arrhythmia, LQT1, is due to IKs potassium channel mutations and is linked to high risk of adrenergic-triggered cardiac…”
Get full text

Impaired IKs channel activation by Ca(2+)-dependent PKC shows correlation with emotion/arousal-triggered events in LQT1 by O-Uchi, Jin, Rice, J Jeremy, Ruwald, Martin H, Parks, Xiaorong Xu, Ronzier, Elsa, Moss, Arthur J, Zareba, Wojciech, Lopes, Coeli M

“…The most common inherited cardiac arrhythmia, LQT1, is due to IKs potassium channel mutations and is linked to high risk of adrenergic-triggered cardiac…”
Get full text

Fluvastatin inhibits Rab5-mediated IKs internalization caused by chronic Ca 2+ -dependent PKC activation by Parks, Xiaorong Xu, Ronzier, Elsa, O-Uchi, Jin, Lopes, Coeli M

“…Statins, in addition to their cholesterol lowering effects, can prevent isoprenylation of Rab GTPase proteins, a key protein family for the regulation of…”
Get full text

A review of synaptic mechanisms of vestibular efferent signaling in turtles: extrapolation to efferent actions in mammals by Jordan, Paivi M, Parks, Xiaorong Xu, Contini, Donatella, Holt, J Chris

“…The vestibular labyrinth of nearly every vertebrate class receives a prominent efferent innervation that originates in the brainstem and ends as bouton…”
Get more information

Stop-codon and C-terminus nonsense mutations are associated with lower risk of cardiac events in Long QT Syndrome Type 1 patients by Ruwald, Martin H., Parks, Xiaorong Xu, Moss, Arthur J., Zareba, Wojciech, Baman, Jayson, McNitt, Scott, Kanters, Jorgen K., Shimizu, Wataru, Wilde, Arthur A., Jons, Christian, Lopes, Coeli M.

Get full text

Impaired IKs channel activation by Ca 2 + -dependent PKC shows correlation with emotion/arousal-triggered events in LQT1 by O-Uchi, Jin, Rice, J. Jeremy, Ruwald, Martin H, Parks, Xiaorong Xu, Ronzier, Elsa, Moss, Arthur J, Zareba, Wojciech, Lopes, Coeli M

“…Abstract Background The most common inherited cardiac arrhythmia, LQT1, is due to IKs potassium channel mutations and is linked to high risk of…”
Get full text