Search Results - "Parks, Jason C"

Advanced paternal age directly impacts mouse embryonic placental imprinting by Denomme, Michelle M, Parks, Jason C, McCallie, Blair R, McCubbin, Nathan I, Schoolcraft, William B, Katz-Jaffe, Mandy G

“…The placental epigenome plays a critical role in regulating mammalian growth and development. Alterations to placental methylation, often observed at imprinted…”
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Increased Systemic Antioxidant Power Ameliorates the Aging-Related Reduction in Oocyte Competence in Mice by Lane, Sydney L, Parks, Jason C, Russ, Jennifer E, Khan, Shaihla A, Schoolcraft, William B, Yuan, Ye, Katz-Jaffe, Mandy G

“…Ovarian aging is associated with elevated oxidative stress and diminished oocyte developmental competence. We aimed to determine the impact of systemic…”
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Paternal aging impacts expression and epigenetic markers as early as the first embryonic tissue lineage differentiation by Denomme, Michelle M, McCallie, Blair R, Haywood, Mary E, Parks, Jason C, Schoolcraft, William B, Katz-Jaffe, Mandy G

“…Advanced paternal age (APA) is associated with adverse outcomes to offspring health, including increased risk for neurodevelopmental disorders. The aim of this…”
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Free-weight versus weight machine resistance exercise on pulse wave reflection and aortic stiffness in resistance-trained individuals by Parks, Jason C., Marshall, Erica M., Tai, Yu Lun, Kingsley, J. Derek

“…The purpose of this study was to compare the vascular responses to acute free-weight (FW) resistance exercise (RE) versus weight machines (WM). Thirty-two…”
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Infertility diagnosis has a significant impact on the transcriptome of developing blastocysts by McCallie, Blair R, Parks, Jason C, Griffin, Darren K, Schoolcraft, William B, Katz-Jaffe, Mandy G

“…Is the human blastocyst transcriptome associated with infertility diagnosis, specifically: polycystic ovaries (PCO), male factor (MF) and unexplained (UE)? The…”
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Hypomethylation and Genetic Instability in Monosomy Blastocysts May Contribute to Decreased Implantation Potential by McCallie, Blair R, Parks, Jason C, Patton, Alyssa L, Griffin, Darren K, Schoolcraft, William B, Katz-Jaffe, Mandy G

“…DNA methylation is a key epigenetic mechanism responsible for gene regulation, chromatin remodeling, and genome stability, playing a fundamental role during…”
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Antioxidant Intervention Attenuates Aging-Related Changes in the Murine Ovary and Oocyte by Katz-Jaffe, Mandy G., Lane, Sydney L., Parks, Jason C., McCallie, Blair R., Makloski, Rachel, Schoolcraft, William B.

“…Advanced maternal age (AMA) is associated with reduced fertility due in part to diminished ovarian follicle quantity, inferior oocyte quality, chromosome…”
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Blastocyst gene expression correlates with implantation potential by Parks, Jason C., B.Sc, McCallie, Blair R., B.Sc, Janesch, Ann M., B.Sc, Schoolcraft, William B., M.D, Katz-Jaffe, Mandy G., Ph.D

“…Objective To investigate the role of the blastocyst in implantation failure. This study examined trophectoderm (TE) gene expression relative to pregnancy…”
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Epigenetic Dysregulation Observed in Monosomy Blastocysts Further Compromises Developmental Potential by Denomme, Michelle M, McCallie, Blair R, Parks, Jason C, Schoolcraft, William B, Katz-Jaffe, Mandy G

“…Epigenetic mechanisms such as DNA methylation regulate genomic imprinting and account for the distinct non-equivalence of the parental genomes in the embryo…”
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Alterations in the sperm histone-retained epigenome are associated with unexplained male factor infertility and poor blastocyst development in donor oocyte IVF cycles by Denomme, Michelle M, McCallie, Blair R, Parks, Jason C, Schoolcraft, William B, Katz-Jaffe, Mandy G

“…Is there a distinct sperm histone-retained epigenetic signature in unexplained male factor infertility patients resulting in compromised blastocyst…”
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The inherited methylome landscape is directly altered with paternal aging and associated with offspring neurodevelopmental disorders by Denomme, Michelle M., Haywood, Mary E., Parks, Jason C., Schoolcraft, William B., Katz‐Jaffe, Mandy G.

“…Paternal aging and the prevalence of neurodevelopmental disorders in offspring are well documented. Yet, the underlying mechanism and the mode of inheritance…”
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Inheritance of epigenetic dysregulation from male factor infertility has a direct impact on reproductive potential by Denomme, Michelle M., McCallie, Blair R., Parks, Jason C., Booher, Keith, Schoolcraft, William B., Katz-Jaffe, Mandy G.

“…To evaluate the epigenetic consequence on the methylome and subsequent transcriptome in euploid blastocysts of male-factor (MF) infertility patients. Methylome…”
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Effects of resistance exercise alone or with caffeine on hemodynamics, autonomic modulation and arterial stiffness in resistance-trained women by Parks, Jason C., Joplin, Meredith C. Paskert, Marshall, Erica M., Kearney, Sarah G., Humm, Stacie M., Kern, Michelle A., Pinzone, Anthony G., Erb, Emily K., Smith, Therese M., Kingsley, J. Derek

“…Aim Both an acute bout of resistance exercise (RE) and caffeine consumption can significantly alter hemodynamics, autonomic modulation, and arterial stiffness,…”
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Autonomic modulation following an acute bout of bench press with and without blood flow restriction by Tai, Yu Lun, Marshall, Erica M., Glasgow, Alaina, Parks, Jason C., Sensibello, Leslie, Kingsley, J. Derek

“…Purpose Traditional resistance exercise decreases vagal tone up to 30 min after an acute bout of resistance exercise, which may increase the risk of…”
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Hemodynamic response and pulse wave analysis after upper- and lower-body resistance exercise with and without blood flow restriction by Tai, Yu Lun, Marshall, Erica M., Parks, Jason C., Kingsley, J. Derek

“…Resistance exercise (RE) has been shown to elevate hemodynamics and pulse wave reflection. However, the effects of acute RE with blood flow restriction (BFR)…”
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Effects of a Cool-Down after Supramaximal Interval Exercise on Autonomic Modulation by Parks, Jason C, Marshall, Erica M, Humm, Stacie M, Erb, Emily K, Kingsley, J Derek

“…Supramaximal interval exercise alters measures of autonomic modulation, while a cool-down may speed the recovery of vagal modulation. The purpose of this study…”
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Cardiac Autonomic Function Following Bilateral and Unilateral Upper Body Acute Resistance Exercise by Marshall, Erica M, Parks, Jason C, Erb, Emily K, Humm, Stacie M, Kingsley, J Derek

“…The purpose of this study was to compare cardiac autonomic responses following bilateral and unilateral upper-body (UB) acute resistance exercise (ARE). In…”
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The impact of infertility diagnosis on embryo-endometrial dialogue by Parks, Jason C, McCallie, Blair R, Patton, Alyssa L, Al-Safi, Zain A, Polotsky, Alex J, Griffin, Darren K, Schoolcraft, William B, Katz-Jaffe, Mandy G

“…Initial stages of implantation involve bi-directional molecular crosstalk between the blastocyst and endometrium. This study investigated an association…”
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Vascular Responses to High-Intensity Battling Rope Exercise between the Sexes by Marshall, Erica M, Parks, Jason C, Singer, Tyler J, Tai, Yu Lun, DeBord, Alexa R, Humm, Stacie M, Kingsley, J. Derek

“…The purpose of the study was to assess high-intensity battling rope exercise (HI-BRE) on hemodynamics, pulse wave reflection and arterial stiffness during…”
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Compromised global embryonic transcriptome associated with advanced maternal age by McCallie, Blair R., Parks, Jason C., Trahan, G. Devon, Jones, Kenneth L., Coate, Breanne D., Griffin, Darren K., Schoolcraft, William B., Katz-Jaffe, Mandy G.

“…Purpose To investigate the global transcriptome and associated embryonic molecular networks impacted with advanced maternal age (AMA). Methods Blastocysts…”
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