Search Results - "Parkkinen, Jyrki"
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Association between periprosthetic tissue metal content, whole blood and synovial fluid metal ion levels and histopathological findings in patients with failed metal-on-metal hip replacement
Published in PloS one (16-05-2018)“…Adverse Reaction to Metal Debris (ARMD) is a major cause of implant failure leading to revision surgery in patients with metal-on-metal (MoM) hip…”
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Analysis of bearing wear, whole blood and synovial fluid metal ion concentrations and histopathological findings in patients with failed ASR hip resurfacings
Published in BMC musculoskeletal disorders (11-12-2017)“…Adverse Reaction to Metal Debris (ARMD) is still a major reason for revision surgeries in patients with metal-on-metal (MoM) hip replacements. ARMD consists of…”
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High blood metal ion levels in 19 of 22 patients with metal-on-metal hinge knee replacements: A cause for concern
Published in Acta orthopaedica (04-05-2017)“…Background and purpose - There has been increasing alarm regarding metal-on-metal (MoM) joint replacements leading to elevated levels of metal ions and adverse…”
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4
Host-specific factors affect the pathogenesis of adverse reaction to metal debris
Published in BMC musculoskeletal disorders (04-05-2019)“…Adverse Reaction to Metal Debris (ARMD) is a major reason for revision surgeries in patients with metal-on-metal (MoM) hip replacements. Most failures are…”
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Outcomes After Flexor Tendon Repair Combined With the Application of Human Amniotic Membrane Allograft
Published in The Journal of hand surgery (American ed.) (01-06-2017)“…Purpose Clinically proven methods to prevent adhesion formation after flexor tendon repair have not yet been established. The aim of this pilot study was to…”
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Mild aseptic lymphocyte-dominated vasculitis-associated lesion (ALVAL)-type reactions also present in patients with failed knee prostheses
Published in Bone & joint research (04-04-2024)“…Metal particles detached from metal-on-metal hip prostheses (MoM-THA) have been shown to cause inflammation and destruction of tissues. To further explore…”
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Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma
Published in Surgical oncology (01-03-2011)“…Abstract Osteosarcoma (OS) is among most common malignant tumour of bone. Matrix metalloproteinases (MMPs) are predominantly associated with poor prognosis of…”
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Genes involved in systemic and arterial bed dependent atherosclerosis--Tampere Vascular study
Published in PloS one (11-04-2012)“…Atherosclerosis is a complex disease with hundreds of genes influencing its progression. In addition, the phenotype of the disease varies significantly…”
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Enhanced Polyamine Catabolism Alters Homeostatic Control of White Adipose Tissue Mass, Energy Expenditure, and Glucose Metabolism
Published in Molecular and Cellular Biology (01-07-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Tibia Adamantinoma Resection and Reconstruction with a Custom-Made Total Tibia Endoprosthesis: A Case Report with 8-Year Follow-Up
Published in Case reports in orthopedics (2018)“…This case study describes a total tibia resection and reconstruction with a custom-made endoprosthetic replacement (EPR) and a long-term, 8-year follow-up. The…”
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Dietary phosphate binding and loading alter kidney angiotensin-converting enzyme mRNA and protein content in 5/6 nephrectomized rats
Published in American journal of nephrology (01-01-2012)“…Vitamin D receptor activation with paricalcitol can modulate the transcription of renin-angiotensin system components in the surgical 5/6 nephrectomy rat model…”
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Polyamines are required for the initiation of rat liver regeneration
Published in Biochemical journal (15-02-2002)“…A large number of studies applying inhibitors of polyamine biosynthesis have indicated that these compounds are required for animal cell proliferation. Here we…”
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Prognostic value of hyaluronan expression in non‐small‐cell lung cancer: Increased stromal expression indicates unfavorable outcome in patients with adenocarcinoma
Published in International journal of cancer (20-01-2001)“…The prognostic value of hyaluronan (HA) was analyzed in a large number of patients (n = 261) with non‐small‐cell lung cancer (NSCLC) by staining archived tumor…”
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Activation of Polyamine Catabolism in Transgenic Rats Induces Acute Pancreatitis
Published in Proceedings of the National Academy of Sciences - PNAS (18-07-2000)“…Polyamines are required for optimal growth and function of cells. Regulation of their cellular homeostasis is therefore tightly controlled. The key regulatory…”
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Reduced Level of CD44 and Hyaluronan Associated with Unfavorable Prognosis in Clinical Stage I Cutaneous Melanoma
Published in The American journal of pathology (01-09-2000)“…The cell surface glycoprotein CD44 and its ligand, hyaluronan (HA), enhance growth and metastatic capacity of melanoma cells in vitro, but their clinical…”
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Immobilisation causes longlasting matrix changes both in the immobilised and contralateral joint cartilage
Published in Annals of the rheumatic diseases (01-04-1997)“…OBJECTIVE The capacity of articular cartilage matrix to recover during 50 weeks of remobilisation after an atrophy caused by 11 weeks of immobilisation of the…”
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Local stimulation of proteoglycan synthesis in articular cartilage explants by dynamic compression in vitro
Published in Journal of orthopaedic research (01-09-1992)“…Cultured bovine articular cartilage was subjected to 50 ms, 0.5-1.0 MPa compressions repeated at intervals of 2-60 s for 1.5 h and simultaneously labeled with…”
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Influence of short-term hydrostatic pressure on organization of stress fibers in cultured chondrocytes
Published in Journal of orthopaedic research (01-07-1995)“…The present study describes changes in the organization of stress fibers that occur in articular cartilage chondrocytes subjected to hydrostatic pressure…”
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Effects of cyclic hydrostatic pressure on proteoglycan synthesis in cultured chondrocytes and articular cartilage explants
Published in Archives of biochemistry and biophysics (01-01-1993)“…Primary chondrocyte cell cultures and explants of bovine articular cartilage were subjected to cyclic hydrostatic pressure in a novel computer-controlled…”
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Histopathological patterns seen around failed metal‐on‐metal hip replacements: Cluster and latent class analysis of patterns of failure
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-04-2020)“…We aimed to establish latent subtypes of histopathological patterns in failed metal‐on‐metal hip replacements. Tissue samples of the synovia from the…”
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