Search Results - "Parkkinen, Jyrki"

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  1. 1

    Association between periprosthetic tissue metal content, whole blood and synovial fluid metal ion levels and histopathological findings in patients with failed metal-on-metal hip replacement by Lehtovirta, Lari, Reito, Aleksi, Parkkinen, Jyrki, Peräniemi, Sirpa, Vepsäläinen, Jouko, Eskelinen, Antti

    Published in PloS one (16-05-2018)
    “…Adverse Reaction to Metal Debris (ARMD) is a major cause of implant failure leading to revision surgery in patients with metal-on-metal (MoM) hip…”
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    Journal Article
  2. 2

    Analysis of bearing wear, whole blood and synovial fluid metal ion concentrations and histopathological findings in patients with failed ASR hip resurfacings by Lehtovirta, Lari, Reito, Aleksi, Parkkinen, Jyrki, Hothi, Harry, Henckel, Johann, Hart, Alister, Eskelinen, Antti

    Published in BMC musculoskeletal disorders (11-12-2017)
    “…Adverse Reaction to Metal Debris (ARMD) is still a major reason for revision surgeries in patients with metal-on-metal (MoM) hip replacements. ARMD consists of…”
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  3. 3

    High blood metal ion levels in 19 of 22 patients with metal-on-metal hinge knee replacements: A cause for concern by Laitinen, Minna, Nieminen, Jyrki, Reito, Aleksi, Pakarinen, Toni-Karri, Suomalainen, Piia, Pamilo, Konsta, Parkkinen, Jyrki, Lont, Tonis, Eskelinen, Antti

    Published in Acta orthopaedica (04-05-2017)
    “…Background and purpose - There has been increasing alarm regarding metal-on-metal (MoM) joint replacements leading to elevated levels of metal ions and adverse…”
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  4. 4

    Host-specific factors affect the pathogenesis of adverse reaction to metal debris by Lehtovirta, Lari, Reito, Aleksi, Lainiala, Olli, Parkkinen, Jyrki, Hothi, Harry, Henckel, Johann, Hart, Alister, Eskelinen, Antti

    Published in BMC musculoskeletal disorders (04-05-2019)
    “…Adverse Reaction to Metal Debris (ARMD) is a major reason for revision surgeries in patients with metal-on-metal (MoM) hip replacements. Most failures are…”
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    Journal Article
  5. 5

    Outcomes After Flexor Tendon Repair Combined With the Application of Human Amniotic Membrane Allograft by Leppänen, Olli V., MD, PhD, Karjalainen, Teemu, MD, PhD, Göransson, Harry, MD, PhD, Hakamäki, Annika, PhD, Havulinna, Jouni, MD, Parkkinen, Jyrki, MD, PhD, Jokihaara, Jarkko, MD, PhD

    Published in The Journal of hand surgery (American ed.) (01-06-2017)
    “…Purpose Clinically proven methods to prevent adhesion formation after flexor tendon repair have not yet been established. The aim of this pilot study was to…”
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  6. 6

    Mild aseptic lymphocyte-dominated vasculitis-associated lesion (ALVAL)-type reactions also present in patients with failed knee prostheses by Rajamäki, Anni, Lehtovirta, Lari, Niemeläinen, Mika, Reito, Aleksi, Parkkinen, Jyrki, Peräniemi, Sirpa, Vepsäläinen, Jouko, Eskelinen, Antti

    Published in Bone & joint research (04-04-2024)
    “…Metal particles detached from metal-on-metal hip prostheses (MoM-THA) have been shown to cause inflammation and destruction of tissues. To further explore…”
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  7. 7

    Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma by Korpi, Jarkko T, Hagström, Jaana, Lehtonen, Niko, Parkkinen, Jyrki, Sorsa, Timo, Salo, Tuula, Laitinen, Minna

    Published in Surgical oncology (01-03-2011)
    “…Abstract Osteosarcoma (OS) is among most common malignant tumour of bone. Matrix metalloproteinases (MMPs) are predominantly associated with poor prognosis of…”
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    Tibia Adamantinoma Resection and Reconstruction with a Custom-Made Total Tibia Endoprosthesis: A Case Report with 8-Year Follow-Up by Nieminen, Jyrki, Kuokkanen, Hannu, Parkkinen, Jyrki, Pakarinen, Toni-Karri, Kask, Gilber, Laitinen, Minna

    Published in Case reports in orthopedics (2018)
    “…This case study describes a total tibia resection and reconstruction with a custom-made endoprosthetic replacement (EPR) and a long-term, 8-year follow-up. The…”
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  11. 11

    Dietary phosphate binding and loading alter kidney angiotensin-converting enzyme mRNA and protein content in 5/6 nephrectomized rats by Eräranta, Arttu, Riutta, Asko, Fan, Meng, Koskela, Jenni, Tikkanen, Ilkka, Lakkisto, Päivi, Niemelä, Onni, Parkkinen, Jyrki, Mustonen, Jukka, Pörsti, Ilkka

    Published in American journal of nephrology (01-01-2012)
    “…Vitamin D receptor activation with paricalcitol can modulate the transcription of renin-angiotensin system components in the surgical 5/6 nephrectomy rat model…”
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  12. 12

    Polyamines are required for the initiation of rat liver regeneration by Alhonen, Leena, Räsänen, Tiina-Liisa, Sinervirta, Riitta, Parkkinen, Jyrki J, Korhonen, Veli-Pekka, Pietilä, Marko, Jänne, Juhani

    Published in Biochemical journal (15-02-2002)
    “…A large number of studies applying inhibitors of polyamine biosynthesis have indicated that these compounds are required for animal cell proliferation. Here we…”
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  13. 13

    Prognostic value of hyaluronan expression in non‐small‐cell lung cancer: Increased stromal expression indicates unfavorable outcome in patients with adenocarcinoma by Pirinen, Risto, Tammi, Raija, Tammi, Markku, Hirvikoski, Pasi, Parkkinen, Jyrki J., Johansson, Risto, Böhm, Jan, Hollmén, Sinikka, Kosma, Veli‐Matti

    Published in International journal of cancer (20-01-2001)
    “…The prognostic value of hyaluronan (HA) was analyzed in a large number of patients (n = 261) with non‐small‐cell lung cancer (NSCLC) by staining archived tumor…”
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  14. 14

    Activation of Polyamine Catabolism in Transgenic Rats Induces Acute Pancreatitis by Alhonen, Leena, Parkkinen, Jyrki J., Keinanen, Tuomo, Sinervirta, Riitta, Herzig, Karl-Heinz, Janne, Juhani

    “…Polyamines are required for optimal growth and function of cells. Regulation of their cellular homeostasis is therefore tightly controlled. The key regulatory…”
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  15. 15

    Reduced Level of CD44 and Hyaluronan Associated with Unfavorable Prognosis in Clinical Stage I Cutaneous Melanoma by Karjalainen, Jari M., Tammi, Raija H., Tammi, Markku I., Eskelinen, Matti J., Ågren, Ulla M., Parkkinen, Jyrki J., Alhava, Esko M., Kosma, Veli-Matti

    Published in The American journal of pathology (01-09-2000)
    “…The cell surface glycoprotein CD44 and its ligand, hyaluronan (HA), enhance growth and metastatic capacity of melanoma cells in vitro, but their clinical…”
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  16. 16

    Immobilisation causes longlasting matrix changes both in the immobilised and contralateral joint cartilage by Jortikka, Matti O, Inkinen, Ritva I, Tammi, Markku I, Parkkinen, Jyrki J, Haapala, Jussi, Kiviranta, Ilkka, Helminen, Heikki J, Lammi, Mikko J

    Published in Annals of the rheumatic diseases (01-04-1997)
    “…OBJECTIVE The capacity of articular cartilage matrix to recover during 50 weeks of remobilisation after an atrophy caused by 11 weeks of immobilisation of the…”
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  17. 17

    Local stimulation of proteoglycan synthesis in articular cartilage explants by dynamic compression in vitro by Parkkinen, J J, Lammi, M J, Helminen, H J, Tammi, M

    Published in Journal of orthopaedic research (01-09-1992)
    “…Cultured bovine articular cartilage was subjected to 50 ms, 0.5-1.0 MPa compressions repeated at intervals of 2-60 s for 1.5 h and simultaneously labeled with…”
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  18. 18

    Influence of short-term hydrostatic pressure on organization of stress fibers in cultured chondrocytes by Parkkinen, J J, Lammi, M J, Inkinen, R, Jortikka, M, Tammi, M, Virtanen, I, Helminen, H J

    Published in Journal of orthopaedic research (01-07-1995)
    “…The present study describes changes in the organization of stress fibers that occur in articular cartilage chondrocytes subjected to hydrostatic pressure…”
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  19. 19

    Effects of cyclic hydrostatic pressure on proteoglycan synthesis in cultured chondrocytes and articular cartilage explants by Parkkinen, J J, Ikonen, J, Lammi, M J, Laakkonen, J, Tammi, M, Helminen, H J

    Published in Archives of biochemistry and biophysics (01-01-1993)
    “…Primary chondrocyte cell cultures and explants of bovine articular cartilage were subjected to cyclic hydrostatic pressure in a novel computer-controlled…”
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  20. 20

    Histopathological patterns seen around failed metal‐on‐metal hip replacements: Cluster and latent class analysis of patterns of failure by Reito, Aleksi, Lehtovirta, Lari, Parkkinen, Jyrki, Eskelinen, Antti

    “…We aimed to establish latent subtypes of histopathological patterns in failed metal‐on‐metal hip replacements. Tissue samples of the synovia from the…”
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