Search Results - "Parkkila, A K"

Carbonic anhydrase IX, MN/CA IX: Analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts by Pastorekova, S, Parkkila, S, Parkkila, AK, Opavsky, R, Zelnik, V, Saarnio, J, Pastorek, J

“…BACKGROUND & AIMS: CA IX (formerly MN protein) is a carbonic anhydrase isoenzyme whose expression is associated with human tumors. However, it has also been…”
Get full text

Identification of carbonic anhydrase XII as the membrane isozyme expressed in the normal human endometrial epithelium by Karhumaa, P., Parkkila, S., Türeci, Ö., Waheed, A., Grubb, J.H., Shah, G., Parkkila, A.-K., Kaunisto, K., Tapanainen, J., Sly, W.S., Rajaniemi, H.

“…Although previous studies demonstrated carbonic anhydrase (CA) activity in the human endometrium, the CA isozyme(s) responsible for this activity has not been…”
Get full text

Immunohistochemical Study of Colorectal Tumors for Expression of a Novel Transmembrane Carbonic Anhydrase, MN/CA IX, with Potential Value as a Marker of Cell Proliferation by Saarnio, Juha, Parkkila, Seppo, Parkkila, Anna-Kaisa, Haukipuro, Kari, Pastoreková, Silvia, Pastorek, Jaromir, Kairaluoma, Matti I., Karttunen, Tuomo J.

“…Carbonic anhydrase isoenzyme IX, MN/CA IX, is a recently discovered member of the carbonic anhydrase (CA) gene family with a suggested function in acid-base…”
Get full text

Mitochondrial Carbonic anhydrase in the nervous system : Expression in neuronal and glial cells by SAID GHANDOUR, M, PARKKILA, Anna-Kaisa, PARKKILA, Seppo, WAHEED, Abdul, SLY, William S

“…Carbonic anhydrase (CA) V is a mitochondrial enzyme that has been reported in several tissues of the gastrointestinal tract. In liver, it participates in…”
Get full text

Distribution of the carbonic anhydrase isoenzymes I, II, and VI in the human alimentary tract by Parkkila, S, Parkkila, A K, Juvonen, T, Rajaniemi, H

“…The distribution of carbonic anhydrase isoenzymes I, II, and VI was studied in the human alimentary tract using specific antibodies to human isoenzymes in…”
Get full text

Expression of a Novel Transmembrane Carbonic Anhydrase Isozyme XII in Normal Human Gut and Colorectal Tumors by Kivelä, Antti, Parkkila, Seppo, Saarnio, Juha, Karttunen, Tuomo J., Kivelä, Jyrki, Parkkila, Anna-Kaisa, Waheed, Abdul, Sly, William S., Grubb, Jeffrey H., Shah, Gul, Türeci, Özlem, Rajaniemi, Hannu

“…Carbonic anhydrase isozyme XII is a recently discovered member of the α-carbonic anhydrase gene family with a suggested role in von Hippel-Lindau gene-mediated…”
Get full text

Expression of the Membrane-associated Carbonic Anhydrase Isozyme XII in the Human Kidney and Renal Tumors by Parkkila, Seppo, Parkkila, Anna-Kaisa, Saarnio, Juha, Kivela, Jyrki, Karttunen, Tuomo J, Kaunisto, Kari, Waheed, Abdul, Sly, William S, Tureci, Ozlem, Virtanen, Ismo, Rajaniemi, Hannu

“…Carbonic anhydrase isozyme XII (CA XII) is a novel membrane-associated protein with a potential role in von Hippel–Lindau carcinogenesis. Although Northern…”
Get full text

Carbonic anhydrase in the alimentary tract. Roles of the different isozymes and salivary factors in the maintenance of optimal conditions in the gastrointestinal canal by Parkkila, S, Parkkila, A K

Get more information

Expression of carbonic anhydrase isoenzymes IV and II in rat epididymal duct by KAUNISTO, K, PARKKILA, S, PARKKILA, A.-K, ABDUL WAHEED, SLY, W. S, RAJANIEMI, H

“…Acidic epididymal fluid mainly accounts for sperm quiescence during storage in the epididymis. Carbonic anhydrase (CA) is an enzyme involved in proton and…”
Get full text

Cell surface expression of HFE protein in epithelial cells, macrophages, and monocytes by Parkkila, S, Parkkila, AK, Waheed, A, Britton, RS, Zhou, XY, Fleming, RE, Tomatsu, S, Bacon, BR, Sly, WS

“…Department of Anatomy and Cell Biology, University of Oulu, Box 5000, FIN-90401 Oulu, Finland. seppo.parkkila@oulu.fi. BACKGROUND AND OBJECTIVE: Most patients…”
Get full text

Carbonic anhydrase IV expression in rat and human gastrointestinal tract regional, cellular, and subcellular localization by Fleming, R E, Parkkila, S, Parkkila, A K, Rajaniemi, H, Waheed, A, Sly, W S

“…Carbonic anhydrase IV (CA IV) is a glycosylphosphatidylinositol-linked isozyme previously identified on the surface of renal tubular epithelium and certain…”
Get full text

Salivary carbonic anhydrase isoenzyme VI is located in the human enamel pellicle by Leinonen, J, Kivelä, J, Parkkila, S, Parkkila, A K, Rajaniemi, H

“…Salivary carbonic anhydrase (CA VI) appears to protect teeth from caries via mechanisms other than direct regulation of salivary pH and buffering capacity. To…”
Get more information

Salivary carbonic anhydrase protects gastroesophageal mucosa from acid injury by PARKKILA, S, PARKKILA, A.-K, LEHTOLA, J, REINILÄ, A, SÖDERVIK, H.-J, RANNISTO, M, RAJANIEMI, H

“…Saliva contains several factors that protect the alimentary canal mucosa against acidity. We measured the secretory carbonic anhydrase (CA VI) levels in the…”
Get full text

Salivary carbonic anhydrase VI concentration and its relation to basic characteristics of saliva in young men by KIVELÄ, J., PARKKILA, S., METTERI, J., PARKKILA, A.-K., TOIVANEN, A., RAJANIEMI, H.

“…Two successive saliva samples were collected under strictly standardized conditions from 209 healthy, selected male soldiers prior to and after breakfast in…”
Get full text

Membrane‐bound carbonic anhydrase IV is expressed in the luminal plasma membrane of the human gallbladder epithelium by Parkkila, S, Parkkila, A, Juvonen, T, Waheed, A, Sly, W S, Saarnio, J, Kaunisto, K, Kellokumpu, S, Rajaniemi, H

“…Alkaline hepatic bile is acidified in the gallbladder to prevent calcium precipitation and gallstone formation. Because membrane‐bound carbonic anhydrase (CA)…”
Get full text

Characterization of CA XIII, a Novel Member of the Carbonic Anhydrase Isozyme Family by Lehtonen, Jonna, Shen, Bairong, Vihinen, Mauno, Casini, Angela, Scozzafava, Andrea, Supuran, Claudiu T., Parkkila, Anna-Kaisa, Saarnio, Juha, Kivelä, Antti J., Waheed, Abdul, Sly, William S., Parkkila, Seppo

“…The carbonic anhydrase (CA) gene family has been reported to consist of at least 11 enzymatically active members and a few inactive homologous proteins. Recent…”
Get full text

Secretory carbonic anhydrase isoenzyme (CA VI) in human serum by Kivela, Jyrki, Parkkila, Seppo, Waheed, Abdul, Parkkila, Anna-Kaisa, Sly, William S, Rajaniemi, Hannu

“…Carbonic anhydrase VI (CA VI) is a secretory isoenzyme that, by analogy to alpha-amylase, is produced in the salivary glands and delivered into saliva. To…”
Get full text

Carbonic anhydrase II in the cerebrospinal fluid: its value as a disease marker by PARKKILA, A.-K., PARKKILA, S., REUNANEN, M., NIEMELÄ, O., TUISKU, S., RAUTAKORPI, I., RAJANIEMI, H.

“…Carbonic anhydrase (CA) II is the predominant CA isoenzyme in the brain of mammals. We have recently developed a dual‐label time‐resolved immunofluorometric…”
Get full text

Carbonic Anhydrase Inhibitor Suppresses Invasion of Renal Cancer Cells in vitro by Parkkila, Seppo, Rajaniemi, Hannu, Parkkila, Anna-Kaisa, Kivela, Jyrki, Waheed, Abdul, Pastorekova, Silvia, Pastorek, Jaromir, Sly, William S.

“…Acidification of the extracellular milieu of malignant tumors is reported to increase the invasive behavior of cancer cells. In normal tissues, production of…”
Get full text

Circadian periodicity in salivary carbonic anhydrase VI concentration by Parkkila, S, Parkkila, A K, Rajaniemi, H

“…Carbonic anhydrase VI (CA VI) is secreted into the saliva by the serous acinar cells of the parotid and submandibular glands. Saliva samples from six healthy…”
Get more information