Search Results - "Parkkila, A"

Carbonic anhydrase IX, MN/CA IX: Analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts by Pastorekova, S, Parkkila, S, Parkkila, AK, Opavsky, R, Zelnik, V, Saarnio, J, Pastorek, J

“…BACKGROUND & AIMS: CA IX (formerly MN protein) is a carbonic anhydrase isoenzyme whose expression is associated with human tumors. However, it has also been…”
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Carbonic Anhydrase Inhibitor Suppresses Invasion of Renal Cancer Cells in vitro by Parkkila, Seppo, Rajaniemi, Hannu, Parkkila, Anna-Kaisa, Kivela, Jyrki, Waheed, Abdul, Pastorekova, Silvia, Pastorek, Jaromir, Sly, William S.

“…Acidification of the extracellular milieu of malignant tumors is reported to increase the invasive behavior of cancer cells. In normal tissues, production of…”
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Human Carbonic Anhydrase XII: cDNA Cloning, Expression, and Chromosomal Localization of a Carbonic Anhydrase Gene that is Overexpressed in Some Renal Cell Cancers by Tureci, Ozlem, Sahin, Ugur, Vollmar, Evi, Siemer, Stefan, Gottert, Elisabeth, Seitz, Gerhard, Parkkila, Anna-Kaisa, Shah, Gul N., Grubb, Jeffrey H., Pfreundschuh, Michael, Sly, William S.

“…We report the cloning and characterization of a tumor-associated carbonic anhydrase (CA) that was identified in a human renal cell carcinoma (RCC) by…”
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Identification of carbonic anhydrase XII as the membrane isozyme expressed in the normal human endometrial epithelium by Karhumaa, P., Parkkila, S., Türeci, Ö., Waheed, A., Grubb, J.H., Shah, G., Parkkila, A.-K., Kaunisto, K., Tapanainen, J., Sly, W.S., Rajaniemi, H.

“…Although previous studies demonstrated carbonic anhydrase (CA) activity in the human endometrium, the CA isozyme(s) responsible for this activity has not been…”
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Immunohistochemical Study of Colorectal Tumors for Expression of a Novel Transmembrane Carbonic Anhydrase, MN/CA IX, with Potential Value as a Marker of Cell Proliferation by Saarnio, Juha, Parkkila, Seppo, Parkkila, Anna-Kaisa, Haukipuro, Kari, Pastoreková, Silvia, Pastorek, Jaromir, Kairaluoma, Matti I., Karttunen, Tuomo J.

“…Carbonic anhydrase isoenzyme IX, MN/CA IX, is a recently discovered member of the carbonic anhydrase (CA) gene family with a suggested function in acid-base…”
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Expression of Membrane-Associated Carbonic Anhydrase XIV on Neurons and Axons in Mouse and Human Brain by Parkkila, Seppo, Parkkila, Anna-Kaisa, Rajaniemi, Hannu, Shah, Gul N., Grubb, Jeffrey H., Waheed, Abdul, Sly, William S.

“…Although long suspected from histochemical evidence for carbonic anhydrase (CA) activity on neurons and observations that CA inhibitors enhance the…”
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Expression of a Novel Transmembrane Carbonic Anhydrase Isozyme XII in Normal Human Gut and Colorectal Tumors by Kivelä, Antti, Parkkila, Seppo, Saarnio, Juha, Karttunen, Tuomo J., Kivelä, Jyrki, Parkkila, Anna-Kaisa, Waheed, Abdul, Sly, William S., Grubb, Jeffrey H., Shah, Gul, Türeci, Özlem, Rajaniemi, Hannu

“…Carbonic anhydrase isozyme XII is a recently discovered member of the α-carbonic anhydrase gene family with a suggested role in von Hippel-Lindau gene-mediated…”
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Characterization of CA XIII, a Novel Member of the Carbonic Anhydrase Isozyme Family by Lehtonen, Jonna, Shen, Bairong, Vihinen, Mauno, Casini, Angela, Scozzafava, Andrea, Supuran, Claudiu T., Parkkila, Anna-Kaisa, Saarnio, Juha, Kivelä, Antti J., Waheed, Abdul, Sly, William S., Parkkila, Seppo

“…The carbonic anhydrase (CA) gene family has been reported to consist of at least 11 enzymatically active members and a few inactive homologous proteins. Recent…”
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Expression of the Membrane-associated Carbonic Anhydrase Isozyme XII in the Human Kidney and Renal Tumors by Parkkila, Seppo, Parkkila, Anna-Kaisa, Saarnio, Juha, Kivela, Jyrki, Karttunen, Tuomo J, Kaunisto, Kari, Waheed, Abdul, Sly, William S, Tureci, Ozlem, Virtanen, Ismo, Rajaniemi, Hannu

“…Carbonic anhydrase isozyme XII (CA XII) is a novel membrane-associated protein with a potential role in von Hippel–Lindau carcinogenesis. Although Northern…”
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Mitochondrial Carbonic anhydrase in the nervous system : Expression in neuronal and glial cells by SAID GHANDOUR, M, PARKKILA, Anna-Kaisa, PARKKILA, Seppo, WAHEED, Abdul, SLY, William S

“…Carbonic anhydrase (CA) V is a mitochondrial enzyme that has been reported in several tissues of the gastrointestinal tract. In liver, it participates in…”
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Distribution of the carbonic anhydrase isoenzymes I, II, and VI in the human alimentary tract by Parkkila, S, Parkkila, A K, Juvonen, T, Rajaniemi, H

“…The distribution of carbonic anhydrase isoenzymes I, II, and VI was studied in the human alimentary tract using specific antibodies to human isoenzymes in…”
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Carbonic anhydrase in the alimentary tract. Roles of the different isozymes and salivary factors in the maintenance of optimal conditions in the gastrointestinal canal by Parkkila, S, Parkkila, A K

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Membrane‐bound carbonic anhydrase IV is expressed in the luminal plasma membrane of the human gallbladder epithelium by Parkkila, S, Parkkila, A, Juvonen, T, Waheed, A, Sly, W S, Saarnio, J, Kaunisto, K, Kellokumpu, S, Rajaniemi, H

“…Alkaline hepatic bile is acidified in the gallbladder to prevent calcium precipitation and gallstone formation. Because membrane‐bound carbonic anhydrase (CA)…”
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Cell surface expression of HFE protein in epithelial cells, macrophages, and monocytes by Parkkila, S, Parkkila, AK, Waheed, A, Britton, RS, Zhou, XY, Fleming, RE, Tomatsu, S, Bacon, BR, Sly, WS

“…Department of Anatomy and Cell Biology, University of Oulu, Box 5000, FIN-90401 Oulu, Finland. seppo.parkkila@oulu.fi. BACKGROUND AND OBJECTIVE: Most patients…”
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Salivary carbonic anhydrase isoenzyme VI is located in the human enamel pellicle by Leinonen, J, Kivelä, J, Parkkila, S, Parkkila, A K, Rajaniemi, H

“…Salivary carbonic anhydrase (CA VI) appears to protect teeth from caries via mechanisms other than direct regulation of salivary pH and buffering capacity. To…”
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Expression of carbonic anhydrase isoenzymes IV and II in rat epididymal duct by KAUNISTO, K, PARKKILA, S, PARKKILA, A.-K, ABDUL WAHEED, SLY, W. S, RAJANIEMI, H

“…Acidic epididymal fluid mainly accounts for sperm quiescence during storage in the epididymis. Carbonic anhydrase (CA) is an enzyme involved in proton and…”
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Carbonic anhydrase IV expression in rat and human gastrointestinal tract regional, cellular, and subcellular localization by Fleming, R E, Parkkila, S, Parkkila, A K, Rajaniemi, H, Waheed, A, Sly, W S

“…Carbonic anhydrase IV (CA IV) is a glycosylphosphatidylinositol-linked isozyme previously identified on the surface of renal tubular epithelium and certain…”
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Salivary carbonic anhydrase protects gastroesophageal mucosa from acid injury by PARKKILA, S, PARKKILA, A.-K, LEHTOLA, J, REINILÄ, A, SÖDERVIK, H.-J, RANNISTO, M, RAJANIEMI, H

“…Saliva contains several factors that protect the alimentary canal mucosa against acidity. We measured the secretory carbonic anhydrase (CA VI) levels in the…”
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Secretory carbonic anhydrase isoenzyme (CA VI) in human serum by Kivela, Jyrki, Parkkila, Seppo, Waheed, Abdul, Parkkila, Anna-Kaisa, Sly, William S, Rajaniemi, Hannu

“…Carbonic anhydrase VI (CA VI) is a secretory isoenzyme that, by analogy to alpha-amylase, is produced in the salivary glands and delivered into saliva. To…”
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Salivary carbonic anhydrase isoenzyme VI by Kivelä, Jyrki, Parkkila, Seppo, Parkkila, Anna‐Kaisa, Leinonen, Jukka, Rajaniemi, Hannu

“…The carbonic anhydrases (CAs) participate in the maintenance of pH homeostasis in various tissues and biological fluids of the human body by catalysing the…”
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