Search Results - "Parkinson, Horace"

Kinetics of Genistein and Its Conjugated Metabolites in Pregnant Sprague-Dawley Rats Following Single and Repeated Genistein Administration by Soucy, Nicole V., Parkinson, Horace D., Sochaski, Mark A., Borghoff, Susan J.

“…Diets high in soy-based products are well known for their estrogenic activity. Genistein, the predominant phytoestrogen present in soy, is known to interact…”
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Pharmacokinetics of monobutylphthalate, the active metabolite of di- n-butylphthalate, in pregnant rats by Kremer, John J., Williams, Carla C., Parkinson, Horace D., Borghoff, Susan J.

“…Di- n -butylphthalate (DBP) is a phthalic acid ester used as a plasticizer and solvent. DBP is a developmental toxicant in rats and mice, with adverse effects…”
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Characterization of metabolites and disposition of tertiary amyl methyl ether in male F344 rats following inhalation exposure by Sumner, Susan C. J., Asgharian, Bahman, Moore, Timothy A., Parkinson, Horace D., Bobbitt, Carol M., Fennell, Timothy R.

“…Tertiary amyl methyl ether (TAME) is a fuel additive used to reduce carbon monoxide in automobile emissions. Because of the potential for human exposure, this…”
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Species and gender differences in the metabolism and distribution of tertiary amyl methyl ether in male and female rats and mice after inhalation exposure or gavage administration by Sumner, Susan C. J., Janszen, Derek B., Asgharian, Bahman, Moore, Timothy A., Parkinson, Horace D., Fennell, Timothy R.

“…Tertiary amyl methyl ether (TAME) is a gasoline fuel additive used to reduce emissions. Understanding the metabolism and distribution of TAME is needed to…”
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Two-year drinking water carcinogenicity study of methyl tertiary-butyl ether (MTBE) in Wistar rats by Dodd, Darol, Willson, Gabrielle, Parkinson, Horace, Bermudez, Edilberto

“…ABSTRACT Methyl tertiary‐butyl ether (MTBE) has been used as a gasoline additive to reduce tailpipe emissions and its use has been discontinued. There remains…”
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Toxicity of methyl tertiary-butyl ether (MTBE) following exposure of Wistar Rats for 13weeks or one year via drinking water by Bermudez, Edilberto, Willson, Gabrielle, Parkinson, Horace, Dodd, Darol

“…Thirteen-week and one-year toxicity studies of methyl tertiary-butyl ether (MTBE) administered in drinking water to Wistar rats were conducted. Male and female…”
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Toxicity of methyl tertiary-butyl ether (MTBE) following exposure of Wistar Rats for 13 weeks or one year via drinking water by Bermudez, Edilberto, Willson, Gabrielle, Parkinson, Horace, Dodd, Darol

“…ABSTRACT Thirteen‐week and one‐year toxicity studies of methyl tertiary‐butyl ether (MTBE) administered in drinking water to Wistar rats were conducted. Male…”
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Physiologically based pharmacokinetic rat model for methyl tertiary -butyl ether; comparison of selected dose metrics following various MTBE exposure scenarios used for toxicity and carcinogenicity evaluation by Borghoff, Susan J, Parkinson, Horace, Leavens, Teresa L

“…Abstract There are a number of cancer and toxicity studies that have been carried out to assess hazard from methyl tertiary -butyl ether (MTBE) exposure via…”
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Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1 by Bauer, Alison K, Faiola, Brenda, Abernethy, Diane J, Marchan, Rosemarie, Pluta, Linda J, Wong, Vicki A, Roberts, Kay, Jaiswal, Anil K, Gonzalez, Frank J, Butterworth, Byron E, Borghoff, Susan, Parkinson, Horace, Everitt, Jeffrey, Recio, Leslie

“…Enzymes that activate and detoxify benzene are likely genetic determinants of benzene-induced toxicity.NAD(P)H: quinone oxidoreductase-1 (NQO1) detoxifies…”
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14C-labeled pulegone and metabolites binding to alpha2u-globulin in kidneys of male F-344 rats by Ferguson, Ling-Jen Chen, Lebetkin, Edward H, Lih, Fred B, Tomer, Kenneth B, Parkinson, Horace D, Borghoff, Susan J, Burka, Leo T

“…Pulegone is a major constituent of pennyroyal oil and a minor component of peppermint oil. Pulegone is biotransformed to menthofuran and menthones…”
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14C-labeled Pulegone and Metabolites Binding to α2u-globulin in Kidneys of Male F-344 Rats by Ferguson, Ling-Jen Chen, Lebetkin, Edward H., Lih, Fred B., Tomer, Kenneth B., Parkinson, Horace D., Borghoff, Susan J., Burka, Leo T.

“…Pulegone is a major constituent of pennyroyal oil and a minor component of peppermint oil. Pulegone is biotransformed to menthofuran and menthones…”
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14 C-labeled Pulegone and Metabolites Binding to α2u-globulin in Kidneys of Male F-344 Rats by Ferguson, Ling-Jen Chen, Lebetkin, Edward H., Lih, Fred B., Tomer, Kenneth B., Parkinson, Horace D., Borghoff, Susan J., Burka, Leo T.

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14C-labeled Pulegone and Metabolites Binding to agr2u-globulin in Kidneys of Male F-344 Rats by Ferguson, Ling-Jen Chen, Lebetkin, Edward H, Lih, Fred B, Tomer, Kenneth B, Parkinson, Horace D, Borghoff, Susan J, Burka, Leo T

“…Pulegone is a major constituent of pennyroyal oil and a minor component of peppermint oil. Pulegone is biotransformed to menthofuran and menthones…”
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super(14)C-labeled Pulegone and Metabolites Binding to alpha 2u-globulin in Kidneys of Male F-344 Rats by Ferguson, Ling-Jen Chen, Lebetkin, Edward H, Lih, Fred B, Tomer, Kenneth B, Parkinson, Horace D, Borghoff, Susan J, Burka, Leo T

“…Various aspects related to super(14)C-labeled pulegone and metabolites binding to alpha 2u-globulin in kidneys of male F-344 rats were investigated. The…”
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Characterization of Metabolites and Disposition of Tertiary Amyl Methyl Ether in Male F-344 Rats Following Inhalation Exposure by Sumner, Susan CJ, Asgharian, Bahman, Moore, Timothy A, Parkinson, Horace D, Bobbit, Carol M, Fennell, Timothy R

“…The gasoline additive tertiary amyl methyl ether (TAME) reduces emissions of carbon dioxide. Male rats inhaled 2500 ppm radiolabeled TAME for six hours,…”
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Genetic susceptibility to benzene-induced toxicity: Role of NADHP: Quinone oxidoreductase-1 by BAUER, Alison K, FAIOLA, Brenda, BORGHOFF, Susan, PARKINSON, Horace, EVERITT, Jeffrey, RECIO, Leslie, ABERNETHY, Diane J, MARCHAN, Rosemarie, PLUTA, Linda J, WONG, Vicki A, ROBERTS, Kay, JAISWAL, Anil K, GONZALEZ, Frank J, BUTTERWORTH, Byron E

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