Search Results - "Parkinson, C J"

Large-scale studies of the association between variation at the TNF/LTA locus and susceptibility to type 2 diabetes by ZEGGINI, E, GROVES, C. J, HATTERSLEY, A. T, MCCARTHY, M. I, PARKINSON, J. R. C, HALFORD, S, OWEN, K. R, FRAYLING, T. M, WALKER, M, HITMAN, G. A, LEVY, J. C, O'RAHILLY, S

“…The proinflammatory cytokine TNF-alpha has been implicated in the pathogenesis of insulin resistance and type 2 diabetes, and variation in the gene encoding…”
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Examining the relationships between the Pro12Ala variant in PPARG and Type 2 diabetes-related traits in UK samples by Zeggini, E., Parkinson, J. R C., Halford, S., Owen, K. R., Walker, M., Hitman, G. A., Levy, J. C., Sampson, M. J., Frayling, T. M., Hattersley, A. T., McCarthy, M. I.

“…Aims  The Pro12Ala polymorphism in the PPARG gene alters amino acid sequence and has shown consistent association with susceptibility to Type 2 diabetes in…”
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Development and Semicommercial Implementation of an Environmentally Benign, Hydrogen Peroxide Mediated Oxidation of Aliphatic Alcohols by Dudas, J, Parkinson, C. J, Cukan, V, Chokwe, T. B

“…A process for the oxidation of an aliphatic alcohol (primary alcohol in C12−C15 region, substrate selected on the basis of a customer requirement) was…”
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Biocatalytic enantiomeric resolution of l-menthol from an eight isomeric menthol mixture through transesterification by Brady, D., Reddy, S., Mboniswa, B., Steenkamp, L.H., Rousseau, A.L., Parkinson, C.J., Chaplin, J., Mitra, R.K., Moutlana, T., Marais, S.F., Gardiner, N.S.

“…[Display omitted] ► Faced with the isolation of eight diastereomers with similar chemical properties we used an enzyme to selectively transform the desired…”
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Sexual dimorphism in relation to adipose tissue and intrahepatocellular lipid deposition in early infancy by Gale, C, Logan, K M, Jeffries, S, Parkinson, J R C, Santhakumaran, S, Uthaya, S, Durighel, G, Alavi, A, Thomas, E L, Bell, J D, Modi, N

“…Sexual dimorphism in adiposity is well described in adults, but the age at which differences first manifest is uncertain. Using a prospective cohort, we…”
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Peptide YY3-36 and Pancreatic Polypeptide Differentially Regulate Hypothalamic Neuronal Activity in Mice In Vivo as Measured by Manganese-Enhanced Magnetic Resonance Imaging by Hankir, M. K., Parkinson, J. R. C., Minnion, J. S., Addison, M. L., Bloom, S. R., Bell, J. D.

“…Peptide YY (PYY) and pancreatic polypeptide (PP) are two appetite suppressing hormones, released post‐prandially from the ileum and pancreas, respectively…”
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The importance of acclimatisation and habituation to experimental conditions when investigating the anorectic effects of gastrointestinal hormones in the rat by ABBOTT, C. R, SMALL, C. J, SAJEDI, A, SMITH, K. L, PARKINSON, J. R. C, BROADHEAD, L. L, GHATEI, M. A, BLOOM, S. R

“…Peptide YY3-36 (PYY(3-36)), glucagon-like peptide-1 (GLP-1), oxyntomodulin and cholecystokinin (CCK) are gastrointestinal-derived hormones that are released…”
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Coordinated changes in energy intake and expenditure following hypothalamic administration of neuropeptides involved in energy balance by Semjonous, N.M, Smith, K.L, Parkinson, J.R.C, Gunner, D.J.L, Liu, Y.L, Murphy, K.G, Ghatei, M.A, Bloom, S.R, Small, C.J

“…Objective: The hypothalamic control of energy balance is regulated by a complex network of neuropeptide-releasing neurons. Although the effect of these…”
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Synthesis of a structurally constrained endoperoxide having antimalarial activity from α-Santonin by Parkinson, C.J., Van der Westhuyzen, C.W.

“…α-Santonin 3 was successfully converted into a biologically active compound 5b containing an endoperoxide group through a photo-oxygenation approach as a…”
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Theoretical UV absorption spectra of hydrodynamically escaping O{sub 2}/CO{sub 2}-rich exoplanetary atmospheres by Gronoff, G., Mertens, C. J., Norman, R. B., Maggiolo, R., Wedlund, C. Simon, Bell, J., Bernard, D., Parkinson, C. J., Vidal-Madjar, A.

“…Characterizing Earth- and Venus-like exoplanets' atmospheres to determine if they are habitable and how they are evolving (e.g., equilibrium or strong erosion)…”
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THEORETICAL UV ABSORPTION SPECTRA OF HYDRODYNAMICALLY ESCAPING O sub(2)/CO sub(2)-RICH EXOPLANETARY ATMOSPHERES by Gronoff, G, Maggiolo, R, Wedlund, C Simon, Mertens, C J, Norman, R B, Bell, J, Bernard, D, Parkinson, C J, Vidal-Madjar, A

“…Characterizing Earth- and Venus-like exoplanets' atmospheres to determine if they are habitable and how they are evolving (e.g., equilibrium or strong erosion)…”
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THEORETICAL UV ABSORPTION SPECTRA OF HYDRODYNAMICALLY ESCAPING O 2 /CO 2 -RICH EXOPLANETARY ATMOSPHERES by Gronoff, G., Maggiolo, R., Wedlund, C. Simon, Mertens, C. J., Norman, R. B., Bell, J., Bernard, D., Parkinson, C. J., Vidal-Madjar, A.

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Metabolic dysfunction following weight cycling in male mice by Schofield, S E, Parkinson, J R C, Henley, A B, Sahuri-Arisoylu, M, Sanchez-Canon, G J, Bell, J D

“…Background: Combatting overweight or obesity can lead to large fluctuations in an individual’s body weight, often referred to as weight cycling or ‘yo-yo’…”
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Bond Dissociation Energies and Radical Stabilization Energies Associated with Substituted Methyl Radicals by Henry, David J, Parkinson, Christopher J, Mayer, Paul M, Radom, Leo

“…Bond dissociation energies (BDEs) and radical stabilization energies (RSEs) associated with a series of 22 monosubstituted methyl radicals (•CH2X) have been…”
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An Assessment of the Performance of High-Level Theoretical Procedures in the Computation of the Heats of Formation of Small Open-Shell Molecules by Henry, David J, Parkinson, Christopher J, Radom, Leo

“…The heats of formation at 0 K (Δf H 0) of 29 small (containing up to 3 heavy atoms) open-shell molecules, with accurately known experimental values, have been…”
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Metathesis Reactions for the Synthesis of Ring-Fused Carbazoles by Pelly, Stephen C, Parkinson, Christopher J, van Otterlo, Willem A. L, de Koning, Charles B

“…The metathesis reaction is used as a key step for the synthesis of the indolo[2,3-a]carbazole core of rebeccamycin 13 and the sulfur analog of furostifoline…”
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Peptide YY 3-36 and Pancreatic Polypeptide Differentially Regulate Hypothalamic Neuronal Activity in Mice In Vivo as Measured by Manganese-Enhanced Magnetic Resonance Imaging: In vivo studies of hypothalamic neuronal activity by Hankir, M. K., Parkinson, J. R. C., Minnion, J. S., Addison, M. L., Bloom, S. R., Bell, J. D.

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Palladium-catalysed arylation of acetoacetate esters to yield 2-arylacetic acid esters by Zeevaart, Jacob G., Parkinson, Christopher J., de Koning, Charles B.

“…The synthesis of a number of 2-arylacetic acid esters using a palladium-catalysed enolate arylation reaction is described. The coupling reaction between ethyl…”
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The Case Hunter v. “The Pall Mall Gazette” by Callender, G. W., Parkinson, J. C.

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The Case Hunter v. “The Pall Mall Gazette.” by Callender, G. W., Parkinson, J. C.

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