Search Results - "Parkin, John D"

Isothiourea-Mediated Organocatalytic Michael Addition–Lactonization on a Surface: Modification of SAMs on Silicon Oxide Substrates by Chisholm, Ross, Parkin, John D, Smith, Andrew D, Hähner, Georg

“…Tailoring the functionality of self-assembled monolayers (SAMs) can be achieved either by depositing prefunctionalized molecules with the appropriate terminal…”
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Contact-free experimental determination of the static flexural spring constant of cantilever sensors using a microfluidic force tool by Parkin, John D, Hähner, Georg

“…Micro- and nanocantilevers are employed in atomic force microscopy (AFM) and in micro- and nanoelectromechanical systems (MEMS and NEMS) as sensing elements…”
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Retinal Basement Membrane Abnormalities and the Retinopathy of Alport Syndrome by Savige, Judy, Liu, John, DeBuc, Delia Cabrera, Handa, James T, Hageman, Gregory S, Wang, Yan Yan, Parkin, John D, Vote, Brendan, Fassett, Rob, Sarks, Shirley, Colville, Deb

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Combining SPR with atomic-force microscopy enables single-molecule insights into activation and suppression of the complement cascade by Makou, Elisavet, Bailey, Richard G., Johnston, Heather, Parkin, John D., Hulme, Alison N., Hähner, Georg, Barlow, Paul N.

“…Activation and suppression of the complement system compete on every serum-exposed surface, host or foreign. Potentially harmful outcomes of this competition…”
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Direct Organocatalytic Enantioselective Functionalization of SiO x Surfaces by Parkin, John D, Chisholm, Ross, Frost, Aileen B, Bailey, Richard G, Smith, Andrew D, Hähner, Georg

“…Traditional methods to prepare chiral surfaces involve either the adsorption of a chiral molecule onto an achiral surface, or adsorption of a species that…”
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Direct Organocatalytic Enantioselective Functionalization of SiOx Surfaces by Parkin, John D., Chisholm, Ross, Frost, Aileen B., Bailey, Richard G., Smith, Andrew D., Hähner, Georg

“…Traditional methods to prepare chiral surfaces involve either the adsorption of a chiral molecule onto an achiral surface, or adsorption of a species that…”
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Retinal basement membrane abnormalities and the retinopathy of Alport syndrome by Savige, Judy, Liu, John, DeBuc, Delia Cabrera, Handa, James T, Hageman, Gregory S, Wang, Yan Yan, Parkin, John D, Vote, Brendan, Fassett, Rob, Sarks, Shirley, Colville, Deb

“…To determine the effects of X-linked and autosomal recessive Alport syndrome on retinal basement membranes and how these result in the characteristic…”
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Direct Organocatalytic Enantioselective Functionalization of SiOx Surfaces by Parkin, John D., Chisholm, Ross, Frost, Aileen B., Bailey, Richard G., Smith, Andrew D., Hähner, Georg

“…Traditional methods to prepare chiral surfaces involve either the adsorption of a chiral molecule onto an achiral surface, or adsorption of a species that…”
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Gene symbol: COL4A5. Disease: Alport Syndrome by Savige, Judy, Tan, Rachel, Colville, Deb, Wang, Yanyan, Parkin, John D, Mathew, Ninan, Savige, Judy

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Direct Organocatalytic Enantioselective Functionalization of SiO x Surfaces by Parkin, John D., Chisholm, Ross, Frost, Aileen B., Bailey, Richard G., Smith, Andrew D., Hähner, Georg

“…Traditional methods to prepare chiral surfaces involve either the adsorption of a chiral molecule onto an achiral surface, or adsorption of a species that…”
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Skin necrosis following subcutaneous heparin injection by Mar, A W, Dixon, B, Ibrahim, K, Parkin, J D

“…Heparin-induced skin necrosis is a rare but serious complication of subcutaneously administered heparin. Previous reports indicate that the skin necrosis is…”
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Microcantilevers: calibration of their spring constants and use as ultrasensitive probes of adsorbed mass by Parkin, John D

“…The dynamic properties of several rectangular and V-shaped microcantilevers were investigated. Particular attention was paid to the higher flexural eigenmodes…”
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Altered methylation of the human MDR1 promoter is associated with acquired multidrug resistance by KANTHARIDIS, P, EL-OSTA, A, DESILVA, M, WALL, D. M. P, HU, X. F, SLATER, A, NADALIN, G, PARKIN, J. D, ZALCBERG, J. R

“…One of the most important forms of drug resistance in acute myeloid leukemia is the multidrug resistance (MDR) phenotype, which is characterized by the…”
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Altered Multidrug Resistance Phenotype Caused by Anthracycline Analogues and Cytosine Arabinoside in Myeloid Leukemia by Hu, Xiu F., Slater, Alison, Kantharidis, Phillip, Rischin, Danny, Juneja, Surender, Rossi, Ralph, Lee, Grace, Parkin, John D., Zalcberg, John R.

“…The expression of P-glycoprotein (Pgp) is often increased in acute myeloid leukemia (AML). However, little is known of the regulation of Pgp expression by…”
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Altered Multidrug Resistance Phenotype Caused by Anthracycline Analogues and Cytosine Arabinoside in Myeloid Leukemia by Hu, Xiu F., Slater, Alison, Kantharidis, Phillip, Rischin, Danny, Juneja, Surender, Rossi, Ralph, Lee, Grace, Parkin, John D., Zalcberg, John R.

“…The expression of P-glycoprotein (Pgp) is often increased in acute myeloid leukemia (AML). However, little is known of the regulation of Pgp expression by…”
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Use of double gradient denaturing gradient gel electrophoresis to detect (AT)n polymorphisms in the UDP-glucuronosyltransferase 1 gene promoter associated with Gilbert's syndrome by Gürtler, Volker, Parkin, John D., Mayall, Barrie C.

“…Gilbert's syndrome, due to reduced hepatic bilirubin glucuronidation is associated with the presence of two extra nucleotides (TA) in the promoter region of…”
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Cyclosporin A and PSC 833 prevent up-regulation of MDR1 expression by anthracyclines in a human multidrug-resistant cell line by HU, X. F, SLATER, A, WALL, D. M, PARKIN, J. D, KANTHARIDIS, P, ZALCBERG, J. R

“…We have previously demonstrated that within 24 h of exposure of the CEM/A7R cell line to epirubicin (EPI), MDR1 gene expression is induced. The aim of the…”
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Cellular and karyotypic characterization of two doxorubicin resistant cell lines isolated from the same parental human leukemia cell line by Zalcberg, J R, Hu, X F, Wall, D M, Mirski, S, Cole, S, Nadalin, G, De Luise, M, Parkin, J D, Vrazas, V, Campbell, L

“…Separate mechanisms underlying the multidrug resistant (MDR) phenotype were identified in 2 independent approaches to select tumour cells resistant to low…”
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Neutropenia due to low-dose methotrexate therapy for psoriasis and rheumatoid arthritis may be fatal by Mayall, B, Poggi, G, Parkin, J D

“…To review experience with neutropenia related to low-dose methotrexate therapy in patients with psoriasis and rheumatoid arthritis. Retrospective review of…”
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P-glycoprotein expression in classical multi-drug resistant leukaemia cells does not correlate with enhanced chloride channel activity by Wang, X, Wall, D M, Parkin, J D, Zalcberg, J R, Kemm, R E

“…1. P-glycoprotein (Pgp) is an ATP-dependent drug efflux pump responsible for classical multi-drug resistance (MDR). 2. Pgp is part of a supergene family of…”
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