Search Results - "Parker, RA"
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Prognosis of patients with acute renal failure requiring dialysis: Results of a multicenter study
Published in American journal of kidney diseases (01-09-1998)“…Despite several decades of clinical experience, the mortality rate for patients with acute renal failure (ARF) requiring dialysis remains high, and the…”
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2
Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes
Published in Journal of medicinal chemistry (28-07-2005)“…Efforts to further elucidate structure−activity relationships (SAR) within our previously disclosed series of β-quaternary amino acid linked…”
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3
Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes
Published in Cell metabolism (01-02-2005)“…Fatty acid binding proteins (FABPs) are cytosolic fatty acid chaperones whose biological role and mechanisms of action are not well understood. Here, we…”
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4
Daytime Sleep Behaviors and Cognitive Performance in Middle- to Older-Aged Adults Living with and without HIV Infection
Published in Nature and science of sleep (01-01-2022)“…We investigated whether daytime sleep behaviors (DSBs) such as frequent daytime sleepiness or napping are associated with worse cognitive performance, and…”
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Systemic administration of a β2-adrenergic receptor agonist reduces mechanical allodynia and suppresses the immune response to surgery in a rat model of persistent post-incisional hypersensitivity
Published in Molecular pain (2021)“…Beta 2 adrenergic receptor (β2 AR) activation in the central and peripheral nervous system has been implicated in nociceptive processing in acute and chronic…”
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6
Home monitoring of breathing rate in people with chronic obstructive pulmonary disease: observational study of feasibility, acceptability, and change after exacerbation
Published in International journal of chronic obstructive pulmonary disease (01-01-2017)“…Telehealth programs to promote early identification and timely self-management of acute exacerbations of chronic obstructive pulmonary diseases (AECOPDs) have…”
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Histologic predictors of renal cell carcinoma response to interleukin-2-based therapy
Published in Journal of immunotherapy (1997) (01-09-2005)“…The authors examined pathology from patients with renal cancer (RCC) treated with IL-2 to determine response rates for clear cell and variant RCC and to…”
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Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis
Published in Nature medicine (01-06-2001)“…The adipocyte fatty-acid-binding protein, aP2, has an important role in regulating systemic insulin resistance and lipid metabolism. Here we demonstrate that…”
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The effects of HIV protease inhibitors atazanavir and lopinavir/ritonavir on insulin sensitivity in HIV-seronegative healthy adults
Published in AIDS (London) (05-11-2004)“…Therapy with some HIV protease inhibitors (PI) contributes to insulin resistance and type 2 diabetes mellitus, by inhibition of insulin-sensitive glucose…”
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10
Clinical Experiences with Desflurane Inhalational Anaesthesia in Horses
Published in Equine veterinary journal (01-09-2014)“…Reasons for performing study Equine general anaesthesia carries a higher risk of perioperative fatality compared with humans and companion animals. Multiple…”
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Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides
Published in AIDS (London) (04-11-2005)“…To determine if particular components of antiretroviral drug regimens are associated with greater insulin resistance, dyslipidemia, and peripheral lipoatrophy…”
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12
The ischemic penumbra : Operationally defined by diffusion and perfusion MRI
Published in Neurology (22-10-1999)“…Identifying tissue at risk for infarction is important in deciding which patients would benefit most from potentially harmful therapies and provides a way to…”
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13
The cascade of HIV care among refugees and nationals in Nakivale Refugee Settlement in Uganda
Published in HIV medicine (01-08-2017)“…Objectives Refugees living in Uganda come from HIV‐endemic countries, and many remain in refugee settlements for over a decade. Our objective was to evaluate…”
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14
Early Changes in Biochemical Markers of Bone Turnover Are Associated with Long-Term Changes in Bone Mineral Density in Elderly Women on Alendronate, Hormone Replacement Therapy, or Combination Therapy: A Three-Year, Double-Blind, Placebo-Controlled, Randomized Clinical Trial
Published in The journal of clinical endocrinology and metabolism (01-05-2005)“…Elderly women on combination therapy with alendronate and hormone replacement for osteoporosis have greater gains in bone mass than those on monotherapy. It is…”
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Clinical and vascular outcome in internal carotid artery versus middle cerebral artery occlusions after intravenous tissue plasminogen activator
Published in Stroke (1970) (01-08-2002)“…Early reperfusion is a predictor of good outcome in acute ischemic stroke. We investigated whether middle cerebral artery (MCA) occlusions have a better…”
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16
Ventrolateral preoptic nucleus contains sleep-active, galaninergic neurons in multiple mammalian species
Published in Neuroscience (01-01-2002)“…The ventrolateral preoptic nucleus (VLPO) is a group of sleep-active neurons that has been identified in the hypothalamus of rats and is thought to inhibit the…”
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Children with Minimal Sensorineural Hearing Loss: Prevalence, Educational Performance, and Functional Status
Published in Ear and hearing (01-10-1998)“…OBJECTIVE:This study was designed to determine the prevalence of minimal sensorineural hearing loss (MSHL) in school-age children and to assess the…”
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Combination Therapy With Hormone Replacement and Alendronate for Prevention of Bone Loss in Elderly Women: A Randomized Controlled Trial
Published in JAMA : the journal of the American Medical Association (21-05-2003)“…CONTEXT Therapy with individual antiresorptive agents has been shown to be effective for prevention and treatment of postmenopausal osteoporosis, but whether…”
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19
Studies Should Be Controlled, Randomized, and Blinded
Published in Clinical pharmacology and therapeutics (01-05-2009)“…Rigorous assessment of the efficacy and safety of a new therapy requires a concurrent control group, randomization, and blinding. The control group allows…”
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Prediction of complications after partial nephrectomy by RENAL nephrometry score
Published in Annals of the Royal College of Surgeons of England (01-09-2014)“…Discussing and planning the appropriate management for suspicious renal masses can be challenging. With the development of nephrometry scoring methods, we…”
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