Search Results - "Parker, Margaret M"

Association Between the New York Sepsis Care Mandate and In-Hospital Mortality for Pediatric Sepsis by Evans, Idris V. R, Phillips, Gary S, Alpern, Elizabeth R, Angus, Derek C, Friedrich, Marcus E, Kissoon, Niranjan, Lemeshow, Stanley, Levy, Mitchell M, Parker, Margaret M, Terry, Kathleen M, Watson, R. Scott, Weiss, Scott L, Zimmerman, Jerry, Seymour, Christopher W

“…IMPORTANCE: The death of a pediatric patient with sepsis motivated New York to mandate statewide sepsis treatment in 2013. The mandate included a 1-hour bundle…”
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The Surviving Sepsis Campaign: Results of an international guideline-based performance improvement program targeting severe sepsis by Levy, Mitchell M, Dellinger, R Phillip, Townsend, Sean R, Linde-Zwirble, Walter T, Marshall, John C, Bion, Julian, Schorr, Christa, Artigas, Antonio, Ramsay, Graham, Beale, Richard, Parker, Margaret M, Gerlach, Herwig, Reinhart, Konrad, Silva, Eliezer, Harvey, Maurene, Regan, Susan, Angus, Derek C

“…OBJECTIVE:The Surviving Sepsis Campaign (SSC or “the Campaign”) developed guidelines for management of severe sepsis and septic shock. A performance…”
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The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis by Levy, Mitchell M., Dellinger, R. Phillip, Townsend, Sean R., Linde-Zwirble, Walter T., Marshall, John C., Bion, Julian, Schorr, Christa, Artigas, Antonio, Ramsay, Graham, Beale, Richard, Parker, Margaret M., Gerlach, Herwig, Reinhart, Konrad, Silva, Eliezer, Harvey, Maurene, Regan, Susan, Angus, Derek C.

“…Objective The Surviving Sepsis Campaign (SSC or “the Campaign”) developed guidelines for management of severe sepsis and septic shock. A performance…”
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Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 by Dellinger, R Phillip, Levy, Mitchell M, Carlet, Jean M, Bion, Julian, Parker, Margaret M, Jaeschke, Roman, Reinhart, Konrad, Angus, Derek C, Brun-Buisson, Christian, Beale, Richard, Calandra, Thierry, Dhainaut, Jean-Francois, Gerlach, Herwig, Harvey, Maurene, Marini, John J, Marshall, John, Ranieri, Marco, Ramsay, Graham, Sevransky, Jonathan, Thompson, B Taylor, Townsend, Sean, Vender, Jeffrey S, Zimmerman, Janice L, Vincent, Jean-Louis

“…OBJECTIVE:To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, “Surviving Sepsis Campaign Guidelines for Management…”
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Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 by Dellinger, R. Phillip, Levy, Mitchell M., Carlet, Jean M., Bion, Julian, Parker, Margaret M., Jaeschke, Roman, Reinhart, Konrad, Angus, Derek C., Brun-Buisson, Christian, Beale, Richard, Calandra, Thierry, Dhainaut, Jean-Francois, Gerlach, Herwig, Harvey, Maurene, Marini, John J., Marshall, John, Ranieri, Marco, Ramsay, Graham, Sevransky, Jonathan, Thompson, B. Taylor, Townsend, Sean, Vender, Jeffrey S., Zimmerman, Janice L., Vincent, Jean-Louis

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Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 by Dellinger, R. Phillip, Levy, Mitchell M., Carlet, Jean M., Bion, Julian, Parker, Margaret M., Jaeschke, Roman, Reinhart, Konrad, Angus, Derek C., Brun-Buisson, Christian, Beale, Richard, Calandra, Thierry, Dhainaut, Jean-Francois, Gerlach, Herwig, Harvey, Maurene, Marini, John J., Marshall, John, Ranieri, Marco, Ramsay, Graham, Sevransky, Jonathan, Thompson, B. Taylor, Townsend, Sean, Vender, Jeffrey S., Zimmerman, Janice L., Vincent, Jean-Louis

“…Objective To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, “Surviving Sepsis Campaign guidelines for management…”
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Rare loss of function variants in the hepatokine gene INHBE protect from abdominal obesity by Deaton, Aimee M., Dubey, Aditi, Ward, Lucas D., Dornbos, Peter, Flannick, Jason, Yee, Elaine, Ticau, Simina, Noetzli, Leila, Parker, Margaret M., Hoffing, Rachel A., Willis, Carissa, Plekan, Mollie E., Holleman, Aaron M., Hinkle, Gregory, Fitzgerald, Kevin, Vaishnaw, Akshay K., Nioi, Paul

“…Identifying genetic variants associated with lower waist-to-hip ratio can reveal new therapeutic targets for abdominal obesity. We use exome sequences from…”
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RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD by Morrow, Jarrett D, Chase, Robert P, Parker, Margaret M, Glass, Kimberly, Seo, Minseok, Divo, Miguel, Owen, Caroline A, Castaldi, Peter, DeMeo, Dawn L, Silverman, Edwin K, Hersh, Craig P

“…Multiple gene expression studies have been performed separately in peripheral blood, lung, and airway tissues to study COPD. We performed RNA-sequencing gene…”
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Cardiac Function and Dysfunction in Sepsis by Fenton, Kimberly E., MD, FAAP, Parker, Margaret M., MD, MCCM

“…Cardiac function and dysfunction are important in the clinical outcomes of sepsis and septic shock. Cardiac dysfunction is not a single entity, but is a broad…”
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Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene by Saferali, Aabida, Yun, Jeong H, Parker, Margaret M, Sakornsakolpat, Phuwanat, Chase, Robert P, Lamb, Andrew, Hobbs, Brian D, Boezen, Marike H, Dai, Xiangpeng, de Jong, Kim, Beaty, Terri H, Wei, Wenyi, Zhou, Xiaobo, Silverman, Edwin K, Cho, Michael H, Castaldi, Peter J, Hersh, Craig P

“…While many disease-associated single nucleotide polymorphisms (SNPs) are associated with gene expression (expression quantitative trait loci, eQTLs), a large…”
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RNA sequencing identifies novel non-coding RNA and exon-specific effects associated with cigarette smoking by Parker, Margaret M, Chase, Robert P, Lamb, Andrew, Reyes, Alejandro, Saferali, Aabida, Yun, Jeong H, Himes, Blanca E, Silverman, Edwin K, Hersh, Craig P, Castaldi, Peter J

“…Cigarette smoking is the leading modifiable risk factor for disease and death worldwide. Previous studies quantifying gene-level expression have documented the…”
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Association of the transthyretin variant V122I with polyneuropathy among individuals of African ancestry by Parker, Margaret M., Damrauer, Scott M., Tcheandjieu, Catherine, Erbe, David, Aldinc, Emre, Hawkins, Philip N., Gillmore, Julian D., Hull, Leland E., Lynch, Julie A., Joseph, Jacob, Ticau, Simina, Flynn-Carroll, Alexander O., Deaton, Aimee M., Ward, Lucas D., Assimes, Themistocles L., Tsao, Philip S., Chang, Kyong-Mi, Rader, Daniel J., Fitzgerald, Kevin, Vaishnaw, Akshay K., Hinkle, Gregory, Nioi, Paul

“…Hereditary transthyretin-mediated (hATTR) amyloidosis is an underdiagnosed, progressively debilitating disease caused by mutations in the transthyretin ( TTR )…”
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Identification of an emphysema-associated genetic variant near TGFB2 with regulatory effects in lung fibroblasts by Parker, Margaret M, Hao, Yuan, Guo, Feng, Pham, Betty, Chase, Robert, Platig, John, Cho, Michael H, Hersh, Craig P, Thannickal, Victor J, Crapo, James, Washko, George, Randell, Scott H, Silverman, Edwin K, San José Estépar, Raúl, Zhou, Xiaobo, Castaldi, Peter J

“…Murine studies have linked TGF-β signaling to emphysema, and human genome-wide association studies (GWAS) studies of lung function and COPD have identified…”
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Quality Improvement or Unintended Consequences? by Parker, Margaret M.

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An international survey : Public awareness and perception of sepsis by RUBULOTTA, Francesca M, RAMSAY, Graham, PARKER, Margaret M, DELLINGER, R. Phillip, LEVY, Mitchell M, POEZE, Martijn

“…Sepsis is a common cause of death throughout the world. Early treatment improves outcome; however, treatment may be delayed if the patient does not present…”
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Sepsis Definitions: I Know It When I See It by Parker, Margaret M.

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Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study by Begum, Ferdouse, Ruczinski, Ingo, Hokanson, John E, Lutz, Sharon M, Parker, Margaret M, Cho, Michael H, Hetmanski, Jacqueline B, Scharpf, Robert B, Crapo, James D, Silverman, Edwin K, Beaty, Terri H

“…Many well-powered genome-wide association studies have identified genetic determinants of self-reported smoking behaviors and measures of nicotine dependence,…”
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Evidence of gene-environment interaction for two genes on chromosome 4 and environmental tobacco smoke in controlling the risk of nonsyndromic cleft palate by Wu, Tao, Schwender, Holger, Ruczinski, Ingo, Murray, Jeffrey C, Marazita, Mary L, Munger, Ronald G, Hetmanski, Jacqueline B, Parker, Margaret M, Wang, Ping, Murray, Tanda, Taub, Margaret, Li, Shuai, Redett, Richard J, Fallin, M Daniele, Liang, Kung Yee, Wu-Chou, Yah Huei, Chong, Samuel S, Yeow, Vincent, Ye, Xiaoqian, Wang, Hong, Huang, Shangzhi, Jabs, Ethylin W, Shi, Bing, Wilcox, Allen J, Jee, Sun Ha, Scott, Alan F, Beaty, Terri H

“…Nonsyndromic cleft palate (CP) is one of the most common human birth defects and both genetic and environmental risk factors contribute to its etiology. We…”
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Joint testing of genotypic and gene-environment interaction identified novel association for BMP4 with non-syndromic CL/P in an Asian population using data from an International Cleft Consortium by Chen, Qianqian, Wang, Hong, Schwender, Holger, Zhang, Tianxiao, Hetmanski, Jacqueline B, Chou, Yah-Huei Wu, Ye, Xiaoqian, Yeow, Vincent, Chong, Samuel S, Zhang, Bo, Jabs, Ethylin Wang, Parker, Margaret M, Scott, Alan F, Beaty, Terri H

“…Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common disorder with complex etiology. The Bone Morphogenetic Protein 4 gene (BMP4) has been…”
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Whole exome association of rare deletions in multiplex oral cleft families by Fu, Jack, Beaty, Terri H., Scott, Alan F., Hetmanski, Jacqueline, Parker, Margaret M., Wilson, Joan E. Bailey, Marazita, Mary L., Mangold, Elisabeth, Albacha‐Hejazi, Hasan, Murray, Jeffrey C., Bureau, Alexandre, Carey, Jacob, Cristiano, Stephen, Ruczinski, Ingo, Scharpf, Robert B.

“…ABSTRACT By sequencing the exomes of distantly related individuals in multiplex families, rare mutational and structural changes to coding DNA can be…”
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