Search Results - "Parker, Helen E."

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein―Coupled Receptor FFAR2 by TOLHURST, Gwen, HEFFRON, Helen, LAM, Yu Shan, PARKER, Helen E, HABIB, Abdella M, DIAKOGIANNAKI, Eleftheria, CAMERON, Jennifer, GROSSE, Johannes, REIMANN, Frank, GRIBBLE, Fiona M

“…Interest in how the gut microbiome can influence the metabolic state of the host has recently heightened. One postulated link is bacterial fermentation of…”
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Identification and Characterization of GLP-1 Receptor-Expressing Cells Using a New Transgenic Mouse Model by RICHARDS, Paul, PARKER, Helen E, ADRIAENSSENS, Alice E, HODGSON, Joshua M, CORK, Simon C, TRAPP, Stefan, GRIBBLE, Fiona M, REIMANN, Frank

“…GLP-1 is an intestinal hormone with widespread actions on metabolism. Therapies based on GLP-1 are highly effective because they increase glucose-dependent…”
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Na+-D-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion by GORBOULEV, Valentin, SCHÜRMANN, Annette, VEYHL-WICHMANN, Maike, SRINIVASAN, Aruna, BALEN, Daniela, BRELJAK, Davorka, REXHEPAJ, Rexhep, PARKER, Helen E, GRIBBLE, Fiona M, REIMANN, Frank, LANG, Florian, WIESE, Stefan, VALLON, Volker, SABOLIC, Ivan, SENDTNER, Michael, KOEPSELL, Hermann, KIPP, Helmut, JASCHKE, Alexander, KLESSEN, Dirk, FRIEDRICH, Alexandra, SCHERNECK, Stephan, RIEG, Timo, CUNARD, Robyn

“…To clarify the physiological role of Na(+)-D-glucose cotransporter SGLT1 in small intestine and kidney, Sglt1(-/-) mice were generated and characterized…”
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Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry by Habib, Abdella M, Richards, Paul, Cairns, Lynne S, Rogers, Gareth J, Bannon, Christopher A. M, Parker, Helen E, Morley, Tom C. E, Yeo, Giles S. H, Reimann, Frank, Gribble, Fiona M

“…The intestine secretes a range of hormones with important local and distant actions, including the control of insulin secretion and appetite. A number of…”
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Glutamine Triggers and Potentiates Glucagon-Like Peptide-1 Secretion by Raising Cytosolic Ca2+ and cAMP by Tolhurst, Gwen, Zheng, Yue, Parker, Helen E, Habib, Abdella M, Reimann, Frank, Gribble, Fiona M

“…The effects of chemical (DPP-4) inhibition and genetic reduction of DPP-4 activity on bone quality were studied in wild-type and ovariectomized mice…”
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A Lab-in-a-Fiber optofluidic device using droplet microfluidics and laser-induced fluorescence for virus detection by Parker, Helen E., Sengupta, Sanghamitra, Harish, Achar V., Soares, Ruben R. G., Joensson, Haakan N., Margulis, Walter, Russom, Aman, Laurell, Fredrik

“…Microfluidics has emerged rapidly over the past 20 years and has been investigated for a variety of applications from life sciences to environmental…”
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Molecular mechanisms underlying nutrient-stimulated incretin secretion by Parker, Helen E, Reimann, Frank, Gribble, Fiona M

“…The incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are released from enteroendocrine cells in the…”
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Author Correction: A Lab-in-a-Fiber optofluidic device using droplet microfluidics and laser-induced fluorescence for virus detection by Parker, Helen E., Sengupta, Sanghamitra, Harish, Achar V., Soares, Ruben R. G., Joensson, Haakan N., Margulis, Walter, Russom, Aman, Laurell, Fredrik

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The associations between physical activity, screen time and weight from 6 to 14 yrs: The Raine Study by Hands, Beth P, Chivers, Paola T, Parker, Helen E, Beilin, Lawrence, Kendall, Garth, Larkin, Dawne

“…Abstract To examine the strength and direction of the relationship between physical activity level, screen use and BMI in a cohort at ages 6, 8, 10 and 14 yrs…”
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Demonstrating the Use of Optical Fibres in Biomedical Sensing: A Collaborative Approach for Engagement and Education by Ehrlich, Katjana, Parker, Helen E, McNicholl, Duncan K, Reid, Peter, Reynolds, Mark, Bussiere, Vincent, Crawford, Graham, Deighan, Angela, Garrett, Alice, Kufcsák, András, Norberg, Dominic R, Spennati, Giulia, Steele, Gregor, Szoor-McElhinney, Helen, Jimenez, Melanie

“…This paper demonstrates how research at the intersection of physics, engineering, biology and medicine can be presented in an interactive and educational way…”
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Selective plane illumination optical endomicroscopy with polymer imaging fibers by Roldán-Varona, Pablo, Ross, Calum A., Rodríguez-Cobo, Luis, López-Higuera, José Miguel, Gaughan, Erin, Dhaliwal, Kevin, Tanner, Michael G., Thomson, Robert R., Parker, Helen E.

“…Imaging fibers are used to perform real-time fluorescence endomicroscopy, in vivo, in situ, with the goal of increasing diagnostic information for a plethora…”
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Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor by Diakogiannaki, Eleftheria, Pais, Ramona, Tolhurst, Gwen, Parker, Helen E., Horscroft, James, Rauscher, Beate, Zietek, Tamara, Daniel, Hannelore, Gribble, Fiona M., Reimann, Frank

“…Aims/hypothesis Ingested protein is a well-recognised stimulus for glucagon-like peptide-1 (GLP-1) release from intestinal L cells. This study aimed to…”
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Glucose Sensing in L Cells: A Primary Cell Study by Reimann, Frank, Habib, Abdella M., Tolhurst, Gwen, Parker, Helen E., Rogers, Gareth J., Gribble, Fiona M.

“…Glucagon-like peptide-1 (GLP-1) is an enteric hormone that stimulates insulin secretion and improves glycaemia in type 2 diabetes. Although GLP-1-based…”
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Characterization and modelling of inter-core coupling in coherent fiber bundles by Perperidis, Antonios, Parker, Helen E, Karam-Eldaly, Ahmed, Altmann, Yoann, Dhaliwal, Kevin, Thomson, Robert R, Tanner, Michael G, McLaughlin, Stephen

“…Recent developments in optical endomicroscopy (OEM) and associated fluorescent SmartProbes present a need for sensitive imaging with high detection…”
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The role of gut endocrine cells in control of metabolism and appetite by Parker, Helen E., Gribble, Fiona M., Reimann, Frank

“…New Findings What is the topic of this review? Gut hormones, especially glucagon‐like peptide‐1 (GLP‐1), have beneficial effects in diabetes and obesity…”
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Frugal filtering optical lenses for point-of-care diagnostics by Long, Joanna, Parker, Helen E, Ehrlich, Katjana, Tanner, Michael G, Dhaliwal, Kevin, Mills, Bethany

“…Infectious diseases are the leading cause of morbidity and mortality in low and middle income countries (LMICs). Rapid diagnosis of infections in LMICs…”
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Molecular detection of Gram-positive bacteria in the human lung through an optical fiber–based endoscope by Mills, Bethany, Megia-Fernandez, Alicia, Norberg, Dominic, Duncan, Sheelagh, Marshall, Adam, Akram, Ahsan R., Quinn, Thomas, Young, Irene, Bruce, Annya M., Scholefield, Emma, Williams, Gareth O. S., Krstajić, Nikola, Choudhary, Tushar R., Parker, Helen E., Tanner, Michael G., Harrington, Kerrianne, Wood, Harry A. C., Birks, Timothy A., Knight, Jonathan C., Haslett, Christopher, Dhaliwal, Kevin, Bradley, Mark, Ucuncu, Muhammed, Stone, James M.

“…Purpose The relentless rise in antimicrobial resistance is a major societal challenge and requires, as part of its solution, a better understanding of…”
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Fibre-based spectral ratio endomicroscopy for contrast enhancement of bacterial imaging and pulmonary autofluorescence by Parker, Helen E, Stone, James M, Marshall, Adam D L, Choudhary, Tushar R, Thomson, Robert R, Dhaliwal, Kevin, Tanner, Michael G

“…Fibre-based optical endomicroscopy (OEM) permits high resolution fluorescence microscopy in endoscopically accessible tissues. Fibred OEM has the potential to…”
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Role of phosphodiesterase and adenylate cyclase isozymes in murine colonic glucagon‐like peptide 1 secreting cells by Friedlander, Ronn S., Moss, Catherine E., Mace, Jessica, Parker, Helen E., Tolhurst, Gwen, Habib, Abdella M., Wachten, Sebastian, Cooper, Dermot M., Gribble, Fiona M., Reimann, Frank

“…BACKGROUND AND PURPOSE Glucagon‐like peptide‐1 (GLP‐1) is secreted from enteroendocrine L‐cells after food intake. Increasing GLP‐1 signalling either through…”
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T1834 Bile Acids Stimulate Glucagon Like Peptide- 2 Secretion from L-Cells; Possible Mediation Through Membrane Receptor TGR5 by Wallis, Katharina, Parker, Helen E, Le Roux, Carel W, Ghatei, Mohammad A, Forbes, Alastair, Gabe, Simon M, Gribble, Fiona, Walters, Julian R

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