Search Results - "Parker, Dylan M"
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It’s Just a Phase: Exploring the Relationship Between mRNA, Biomolecular Condensates, and Translational Control
Published in Frontiers in genetics (27-06-2022)“…Cells spatially organize their molecular components to carry out fundamental biological processes and guide proper development. The spatial organization of RNA…”
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Journal Article -
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Shining light on DHX9: UV-induced stress granules illuminate protective mechanisms for daughter cell resilience
Published in Molecular cell (18-04-2024)“…In a recent article in Cell, Zhou et al. investigate the origins, composition, and biological consequences of UV-induced stress granules. They find that…”
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Journal Article -
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A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2
Published in G3 : genes - genomes - genetics (01-05-2018)“…The ELT-2 GATA factor normally functions in differentiation of the endoderm, downstream of endoderm specification. We have previously shown that, if ELT-2 is…”
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Journal Article -
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The ERM-1 membrane-binding domain directs erm-1 mRNA localization to the plasma membrane in the C. elegans embryo
Published in Development (Cambridge) (15-11-2022)“…mRNA localization and transport are integral in regulating gene expression. In Caenorhabditis elegans embryos, the maternally inherited mRNA erm-1…”
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Journal Article -
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Widespread roles for piRNAs and WAGO-class siRNAs in shaping the germline transcriptome of Caenorhabditis elegans
Published in Nucleic acids research (28-02-2020)“…Piwi-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) are distinct classes of small RNAs required for proper germline development. To identify the…”
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Journal Article -
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mRNA localization is linked to translation regulation in the Caenorhabditis elegans germ lineage
Published in Development (Cambridge) (08-07-2020)“…early embryos generate cell-specific transcriptomes despite lacking active transcription, thereby presenting an opportunity to study mechanisms of…”
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Journal Article -
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Improved Methods for Single-Molecule Fluorescence In Situ Hybridization and Immunofluorescence in Caenorhabditis elegans Embryos
Published in Current protocols (01-11-2021)“…Visualization of gene products in Caenorhabditis elegans has provided insights into the molecular and biological functions of many novel genes in their native…”
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MRNA Localization in Caenorhabditis elegans Embryogenesis
Published 01-01-2021“…From guiding cell specification to regulating protein output, post-transcriptional regulation of mRNA is essential for life. As a result, many mechanisms…”
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Dissertation -
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mRNA localization is linked to translation regulation in the Caenorhabditis elegans germ lineage
Published in Development (Cambridge) (01-01-2020)“…Caenorhabditis elegans early embryos generate cell-specific transcriptomes despite lacking active transcription, thereby presenting an opportunity to study…”
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Journal Article -
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The Effect of Intra-articular Hyaluronic Acid Injections and Payer Coverage on Total Knee Arthroplasty Procedures: Evidence From Large US Claims Database
Published in Arthroplasty today (01-02-2023)“…There is debate regarding the efficacy of intra-articular (IA) hyaluronic acid (HA) injections for the management of knee osteoarthritis (OA). This study aimed…”
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