Search Results - "Parker, Dawn DiGiugno"
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Inhibitors of HIV-1 attachment. Part 4: A study of the effect of piperazine substitution patterns on antiviral potency in the context of indole-based derivatives
Published in Bioorganic & medicinal chemistry letters (01-09-2009)“…4-Fluoro- and 4-methoxy-1-(4-benzoylpiperazin-1-yl)-2-(1 H-indol-3-yl)ethane-1,2-dione ( 2 and 3, respectively) have been characterized as potent inhibitors of…”
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Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment. 5. An Evolution from Indole to Azaindoles Leading to the Discovery of 1-(4-Benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-488043), a Drug Candidate That Demonstrates Antiviral Activity in HIV-1-Infected Subjects
Published in Journal of medicinal chemistry (10-12-2009)“…Azaindole derivatives derived from the screening lead 1-(4-benzoylpiperazin-1-yl)-2-(1H-indol-3-yl)ethane-1,2-dione (1) were prepared and characterized to…”
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Corrigendum to “Inhibitors of HIV-1 attachment. Part 4: A study of the effect of piperazine substitution patterns on antiviral potency in the context of indole-based derivatives” [Bioorg. Med. Chem. Lett. 19 (2009) 5140]
Published in Bioorganic & medicinal chemistry letters (15-02-2010)Get full text
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