Search Results - "Parker, Alexander N"
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Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels
Published in Circulation (New York, N.Y.) (22-02-2011)“…C-reactive protein (CRP) is a heritable marker of chronic inflammation that is strongly associated with cardiovascular disease. We sought to identify genetic…”
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Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci
Published in PLoS genetics (01-04-2011)“…Soluble ICAM-1 (sICAM-1) is an endothelium-derived inflammatory marker that has been associated with diverse conditions such as myocardial infarction,…”
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Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study
Published in PLoS genetics (01-12-2008)“…Type 2 diabetes is a leading cause of morbidity and mortality. While genetic variants have been found to influence the risk of type 2 diabetes mellitus,…”
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4
New loci associated with kidney function and chronic kidney disease
Published in Nature genetics (01-05-2010)“…Caroline Fox and colleagues report results of a large genome-wide association meta-analysis and replication study for indices of renal function. Their work…”
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Two independent alleles at 6q23 associated with risk of rheumatoid arthritis
Published in Nature genetics (01-12-2007)“…To identify susceptibility alleles associated with rheumatoid arthritis, we genotyped 397 individuals with rheumatoid arthritis for 116,204 SNPs and carried…”
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Novel Associations of CPS1, MUT, NOX4, and DPEP1 With Plasma Homocysteine in a Healthy Population: A Genome-Wide Evaluation of 13 974 Participants in the Women's Genome Health Study
Published in Circulation. Cardiovascular genetics (01-04-2009)“…Novel Associations of CPS1, MUT, NOX4, and DPEP1 With Plasma Homocysteine in a Healthy Population A Genome-Wide Evaluation of 13 974 Participants in the…”
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Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein
Published in PloS one (13-03-2015)“…Pleiotropic genetic variants have independent effects on different phenotypes. C-reactive protein (CRP) is associated with several cardiometabolic phenotypes…”
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Genome-Wide Association Analysis of Soluble ICAM-1 Concentration Reveals Novel Associations at the NFKBIK, PNPLA3, RELA, and SH2B3 Loci: e1001374
Published in PLoS genetics (01-04-2011)“…Soluble ICAM-1 (sICAM-1) is an endothelium-derived inflammatory marker that has been associated with diverse conditions such as myocardial infarction,…”
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Novel Association of HK1 with Glycated Hemoglobin in a Non-Diabetic Population: A Genome-Wide Evaluation of 14,618 Participants in the Women's Genome Health Study: e1000312
Published in PLoS genetics (01-12-2008)“…Type 2 diabetes is a leading cause of morbidity and mortality. While genetic variants have been found to influence the risk of type 2 diabetes mellitus,…”
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