Search Results - "Parke, Hal R. I"
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Catalytic enantioselective arylative cyclizations of alkynyl 1,3-diketones by 1,4-rhodium() migration
Published in Chemical science (Cambridge) (14-03-2020)“…The enantioselective synthesis of densely functionalized polycarbocycles by the rhodium( i )-catalyzed reaction of arylboronic acids with 1,3-diketones is…”
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Journal Article -
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Free–Wilson Analysis of Comprehensive Data on Phosphoinositide-3-kinase (PI3K) Inhibitors Reveals Importance of N‑Methylation for PI3Kδ Activity
Published in Journal of medicinal chemistry (27-11-2019)“…Phosphoinositide-3-kinase δ (PI3Kδ) is a critical regulator of cell growth and transformation and has been explored as a therapeutic target for a range of…”
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Journal Article