Search Results - "Parke, Evan A."

Langerhans Cells Activate Naive Self-Antigen-Specific CD8 T Cells in the Steady State by Mayerova, Dita, Parke, Evan A., Bursch, Laura S., Odumade, Oludare A., Hogquist, Kristin A.

“…TCR transgenic mice that express a peptide antigen in keratinocytes develop a lethal CD8 T cell-dependent autoimmune disease. We employed an adoptive transfer…”
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Alanine Scanning Mutagenesis of an αβ T Cell Receptor: Mapping the Energy of Antigen Recognition by Manning, Thomas C, Schlueter, Carol J, Brodnicki, Thomas C, Parke, Evan A, Speir, Jeffrey A, Garcia, K.Christopher, Teyton, Luc, Wilson, Ian A, Kranz, David M

“…The T cell receptor (TCR) from the alloreactive T lymphocyte 2C recognizes a nonamer peptide QL9 complexed with the MHC class I molecule H2-Ld. Forty-two…”
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A Spontaneous CD8 T Cell-Dependent Autoimmune Disease to an Antigen Expressed Under the Human Keratin 14 Promoter by McGargill, Maureen A, Mayerova, Dita, Stefanski, Heather E, Koehn, Brent, Parke, Evan A, Jameson, Stephen C, Panoskaltsis-Mortari, Angela, Hogquist, Kristin A

“…Using a previously described human keratin 14 (K14) promoter, we created mice expressing a peptide Ag (OVAp) in epithelial cells of the skin, tongue,…”
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Effects of complementarity determining region mutations on the affinity of an alpha/beta T cell receptor: measuring the energy associated with CD4/CD8 repertoire skewing by Manning, T C, Parke, E A, Teyton, L, Kranz, D M

“…It has been proposed that the generally low affinities of T cell receptors (TCRs) for their peptide-major histocompatibility complex (pMHC) ligands (Kd…”
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Mapping the energy of superantigen Staphylococcus enterotoxin C3 recognition of an alpha/beta T cell receptor using alanine scanning mutagenesis by Churchill, H R, Andersen, P S, Parke, E A, Mariuzza, R A, Kranz, D M

“…Binding of the T cell receptor (TCR) to a bacterial superantigen (SAG) results in stimulation of a large population of T cells and subsequent inflammatory…”
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