Search Results - "Park, Yun Yong"

Microbiota-Derived Lactate Accelerates Intestinal Stem-Cell-Mediated Epithelial Development by Lee, Yong-Soo, Kim, Tae-Young, Kim, Yeji, Lee, Su-Hyun, Kim, Seungil, Kang, Sung Wan, Yang, Jin-Young, Baek, In-Jeoung, Sung, Young Hoon, Park, Yun-Yong, Hwang, Sung Wook, O, Eunju, Kim, Kwang Soon, Liu, Siqing, Kamada, Nobuhiko, Gao, Nan, Kweon, Mi-Na

“…Symbionts play an indispensable role in gut homeostasis, but underlying mechanisms remain elusive. To clarify the role of lactic-acid-producing bacteria (LAB)…”
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AMPK promotes antitumor immunity by downregulating PD-1 in regulatory T cells via the HMGCR/p38 signaling pathway by Pokhrel, Ram Hari, Acharya, Suman, Ahn, Jae-Hee, Gu, Ye, Pandit, Mahesh, Kim, Jong-Oh, Park, Yun-Yong, Kang, Ben, Ko, Hyun-Jeong, Chang, Jae-Hoon

“…AMP-activated protein kinase (AMPK) is a metabolic sensor that maintains energy homeostasis. AMPK functions as a tumor suppressor in different cancers;…”
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Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer by Kang, Myoung-Hee, Choi, Hyunji, Oshima, Masanobu, Cheong, Jae-Ho, Kim, Seokho, Lee, Jung Hoon, Park, Young Soo, Choi, Hueng-Sik, Kweon, Mi-Na, Pack, Chan-Gi, Lee, Ju-Seog, Mills, Gordon B., Myung, Seung-Jae, Park, Yun-Yong

“…The principle factors underlying gastric cancer (GC) development and outcomes are not well characterized resulting in a paucity of validated therapeutic…”
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Krüppel-Like Factor 12 Promotes Colorectal Cancer Growth through Early Growth Response Protein 1 by Kim, Sun-Hee, Park, Yun-Yong, Cho, Sung-Nam, Margalit, Ofer, Wang, Dingzhi, DuBois, Raymond N

“…Krüppel-like factor 12 (KLF12) is a transcription factor that plays a role in normal kidney development and repression of decidualization. KLF12 is frequently…”
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Fibroblast-associated tumour microenvironment induces vascular structure-networked tumouroid by Lee, Sang Woo, Kwak, Hyeong Seob, Kang, Myoung-Hee, Park, Yun-Yong, Jeong, Gi Seok

“…In vitro three-dimensional (3D) tumour models mimic natural cancer tissue in vivo , bridging the gap between conventional 2D in vitro testing and animal…”
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Targeting phosphomevalonate kinase enhances radiosensitivity via ubiquitination of the replication protein A1 in lung cancer cells by Park, Seok Soon, Kwon, Mi Ri, Ju, Eun Jin, Shin, Seol Hwa, Park, Jin, Ko, Eun Jung, Son, Ga Won, Lee, Hye Won, Kim, Yeon Joo, Moon, Gyeong Joon, Park, Yun‐Yong, Song, Si Yeol, Jeong, Seong‐Yun, Choi, Eun Kyung

“…Radiotherapy (RT) plays an important role in localized lung cancer treatments. Although RT locally targets and controls malignant lesions, RT resistance…”
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Genomic analysis of nuclear receptors and miRNAs identifies a role for the NR3C1/miR-200 axis in colon cancer by Park, Yun-Yong

“…Background Nuclear receptors (NRs) are crucial transcription factors involved in cell proliferation, metabolism and homeostasis. Through the development of…”
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Genome-wide transcriptome profiling of homologous recombination DNA repair by Peng, Guang, Chun-Jen Lin, Curtis, Mo, Wei, Dai, Hui, Park, Yun-Yong, Kim, Soo Mi, Peng, Yang, Mo, Qianxing, Siwko, Stefan, Hu, Ruozhen, Lee, Ju-Seog, Hennessy, Bryan, Hanash, Samir, Mills, Gordon B., Lin, Shiaw-Yih

“…Homologous recombination (HR) repair deficiency predisposes to cancer development, but also sensitizes cancer cells to DNA damage-inducing therapeutics. Here…”
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Yes‐associated protein 1 and transcriptional coactivator with PDZ‐binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma by Park, Yun‐Yong, Sohn, Bo Hwa, Johnson, Randy L., Kang, Myoung‐Hee, Kim, Sang Bae, Shim, Jae‐Jun, Mangala, Lingegowda S., Kim, Ji Hoon, Yoo, Jeong Eun, Rodriguez‐Aguayo, Cristian, Pradeep, Sunila, Hwang, Jun Eul, Jang, Hee‐Jin, Lee, Hyun‐Sung, Rupaimoole, Rajesha, Lopez‐Berestein, Gabriel, Jeong, Woojin, Park, Inn Sun, Park, Young Nyun, Sood, Anil K., Mills, Gordon B., Lee, Ju‐Seog

“…Metabolic activation is a common feature of many cancer cells and is frequently associated with the clinical outcomes of various cancers, including…”
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PAUF Induces Migration of Human Pancreatic Cancer Cells Exclusively via the TLR4/MyD88/NF-κB Signaling Pathway by Youn, So Eun, Jiang, Fen, Won, Hye Yun, Hong, Da Eun, Kang, Tae Heung, Park, Yun-Yong, Koh, Sang Seok

“…PAUF, a tumor-promoting protein secreted by cancer cells, exerts paracrine effects on immune cells through TLR4 receptors expressed on immune cell surfaces…”
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Gene Expression Signature-Based Prognostic Risk Score in Gastric Cancer by JAE YONG CHO, JAE YUN LIM, SUNG HOON NOH, EUN SUNG PARK, CHU, In-Sun, WAUN KI HONG, AJANI, Jaffer A, LEE, Ju-Seog, JAE HO CHEONG, PARK, Yun-Yong, YOON, Se-Lyun, SOO MI KIM, KIM, Sang-Bae, KIM, Hoguen, SOON WON HONG, YOUNG NYUN PARK

“…Despite continual efforts to develop a prognostic model of gastric cancer by using clinical and pathologic parameters, a clinical test that can discriminate…”
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RNA-binding protein NONO contributes to cancer cell growth and confers drug resistance as a theranostic target in TNBC by Kim, Seong-Jin, Ju, Jin-Sung, Kang, Myoung-Hee, Eun, Ji Won, Kim, Young Ha, Raninga, Prahlad V, Khanna, Kum Kum, Győrffy, Balázs, Pack, Chan-Gi, Han, Hee-Dong, Lee, Hee Jin, Gong, Gyungyub, Shin, Yong, Mills, Gordon B, Eyun, Seong-Il, Park, Yun-Yong

“…Breast cancer (BC) is one of the most common cancers in women. TNBC (Triple-negative breast cancer) has limited treatment options and still lacks viable…”
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miR-96-5p targets PTEN to mediate sunitinib resistance in clear cell renal cell carcinoma by Park, Sang Eun, Kim, Wonju, Hong, Ji-Ye, Kang, Dayeon, Park, Seulki, Suh, Jungyo, You, Dalsan, Park, Yun-Yong, Suh, Nayoung, Hwang, Jung Jin, Kim, Choung-Soo

“…A multiple receptor tyrosine kinase inhibitor, sunitinib, is a first-line therapy for clear cell renal cell carcinoma (CCRCC). Unfortunately, it has the major…”
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Gene expression signature analysis identifies vorinostat as a candidate therapy for gastric cancer by Claerhout, Sofie, Lim, Jae Yun, Choi, Woonyoung, Park, Yun-Yong, Kim, Kyounghyun, Kim, Sang-Bae, Lee, Ju-Seog, Mills, Gordon B, Cho, Jae Yong

“…Gastric cancer continues to be one of the deadliest cancers in the world and therefore identification of new drugs targeting this type of cancer is thus of…”
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The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer by Cascone, Tina, Xu, Li, Lin, Heather Y, Liu, Wenbin, Tran, Hai T, Liu, Yuan, Howells, Kathryn, Haddad, Vincent, Hanrahan, Emer, Nilsson, Monique B, Cortez, Maria A, Giri, Uma, Kadara, Humam, Saigal, Babita, Park, Yun-Yong, Peng, Weiyi, Lee, Ju-Seog, Ryan, Anderson J, Jüergensmeier, Juliane M, Herbst, Roy S, Wang, Jing, Langley, Robert R, Wistuba, Ignacio I, Lee, Jack J, Heymach, John V

“…Resistance to VEGFR inhibitors is a major obstacle in the treatment of non-small cell lung cancer (NSCLC). We investigated the cellular mechanisms mediating…”
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Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells by Timilshina, Maheshwor, You, Zhiwei, Lacher, Sonja M., Acharya, Suman, Jiang, Liyuan, Kang, Youra, Kim, Jung-Ae, Chang, Hyeun Wook, Kim, Keuk-Jun, Park, Byoungduck, Song, Jae-Hyoung, Ko, Hyun-Jeong, Park, Yun-Yong, Ma, Min-Jung, Nepal, Mahesh Raj, Jeong, Tae Cheon, Chung, Yeonseok, Waisman, Ari, Chang, Jae-Hoon

“…The function of regulatory T (Treg) cells depends on lipid oxidation. However, the molecular mechanism by which Treg cells maintain lipid metabolism after…”
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AMPK-HIF-1α signaling enhances glucose-derived de novo serine biosynthesis to promote glioblastoma growth by Yun, Hye Jin, Li, Min, Guo, Dong, Jeon, So Mi, Park, Su Hwan, Lim, Je Sun, Lee, Su Bin, Liu, Rui, Du, Linyong, Kim, Seok-Ho, Shin, Tae Hwan, Eyun, Seong-Il, Park, Yun-Yong, Lu, Zhimin, Lee, Jong-Ho

“…Cancer cells undergo cellular adaptation through metabolic reprogramming to sustain survival and rapid growth under various stress conditions. However, how…”
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Selective delivery of PLXDC1 small interfering RNA to endothelial cells for anti-angiogenesis tumor therapy using CD44-targeted chitosan nanoparticles for epithelial ovarian cancer by Kim, Ga Hee, Won, Ji Eun, Byeon, Yeongseon, Kim, Min Gi, Wi, Tae In, Lee, Jae Myeong, Park, Yun-Yong, Lee, Jeong-Won, Kang, Tae Heung, Jung, In Duk, Shin, Byung Cheol, Ahn, Hyung Jun, Lee, Young Joo, Sood, Anil K., Han, Hee Dong, Park, Yeong-Min

“…Angiogenesis plays an essential role in the growth and metastasis of tumor cells, and the modulation of angiogenesis can be an effective approach for cancer…”
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The resident pathobiont Staphylococcus xylosus in Nfkbiz-deficient skin accelerates spontaneous skin inflammation by Kim, Yeji, Lee, Yong-Soo, Yang, Jin-Young, Lee, Su-Hyun, Park, Yun-Yong, Kweon, Mi-Na

“…IκBζ, which is encoded by the Nfkbiz gene, is a member of the nuclear IκB family of proteins that act as transcriptional regulators via association with NF-κB…”
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A biocomposite-based rapid sampling assay for circulating cell-free DNA in liquid biopsy samples from human cancers by Koo, Bonhan, Jun, Eunsung, Liu, Huifang, Kim, Eo Jin, Park, Yun-Yong, Lim, Seok-Byung, Kim, Song Cheol, Shin, Yong

“…Cell-free nucleic acids (cfNAs) in liquid biopsy samples are emerging as important biomarkers for cancer diagnosis and monitoring, and for predicting treatment…”
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