Search Results - "Park, Young Shik"

Diminished expression of dihydropteridine reductase is a potent biomarker for hypertensive vessels by Lee, Chang-Kwon, Han, Jin Soo, Won, Kyung-Jong, Jung, Seung-Hyo, Park, Hyo-Jun, Lee, Hwan Myung, Kim, Junghwan, Park, Young Shik, Kim, Hyun-Jung, Park, Pyo-Jam, Park, Tae-Kyu, Kim, Bokyung

“…To identify the new targets for hypertension, we analyzed the protein expression profiles of aortic smooth muscle in spontaneously hypertensive rats (SHR) of…”
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Enzyme Hydrolysates of Ginseng Marc Polysaccharides Promote the Phagocytic Activity of Macrophages Via Activation of TLR2 and Mer Tyrosine Kinase by Seo, Jeong Yeon, Choi, Ji Won, Lee, Jae Yeon, Park, Young Shik, Park, Yong Il

“…Although ginseng marc is a by-product obtained during manufacturing of various commercial ginseng products and has been routinely discarded as a waste, it…”
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Dictyostelium discoideum Ax2 as an Assay System for Screening of Pharmacological Chaperones for Phenylketonuria Mutations by Kim, Yu-Min, Yang, Yun Gyeong, Kim, Hye-Lim, Park, Young Shik

“…In this study, we developed an assay system for missense mutations in human phenylalanine hydroxylases (hPAHs). To demonstrate the reliability of the system,…”
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Maintenance of cellular tetrahydrobiopterin homeostasis by Kim, Hye-Lim, Park, Young-Shik

“…Tetrahydrobiopterin (BH4) is a multifunctional cofactor of aromatic amino acid hydroxylases and nitric oxide synthase (NOS) as well as an intracellular…”
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Supplementation of a Fermented Soybean Extract Reduces Body Mass and Prevents Obesity in High Fat Diet-Induced C57BL/6J Obese Mice by Lee, Jae Yeon, Aravinthan, Adithan, Park, Young Shik, Hwang, Kyo Yeol, Seong, Su-Il, Hwang, Kwontack

“…Obesity is a growing health problem that many countries face, mostly due to the consumption of a Westernized diet. In this present study we observed the…”
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Altered sugar donor specificity and catalytic activity of pteridine glycosyltransferases by domain swapping or site-directed mutagenesis by Kim, Hye-Lim, Kim, Ae Hyun, Park, Mi Bi, Lee, Soo-Woong, Park, Young Shik

“…CY-007 and CY-049 pteridine glycosyltransferases (PGTs) that differ in sugar donor specificity to catalyze either glucose or xylose transfer to…”
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Structure of Chlorobium tepidum Sepiapterin Reductase Complex Reveals the Novel Substrate Binding Mode for Stereospecific Production of l-threo-Tetrahydrobiopterin by Supangat, Supangat, Seo, Kyung Hye, Choi, Yong Kee, Park, Young Shik, Son, Daeyoung, Han, Chang-deok, Lee, Kon Ho

“…Sepiapterin reductase (SR) is involved in the last step of tetrahydrobiopterin (BH4) biosynthesis by reducing the di-keto group of 6-pyruvoyl tetrahydropterin…”
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Organic Acid Profiling Analysis in Culture Media of Lactic Acid Bacteria by Gas Chromatography-Mass Spectrometry by Jae Yeon Lee, Duc-toan Nguyen, Young Shik Park, Kyo Yeol Hwang, Yong Seok Cho, Kyung-don Kang, Jaehwan Yoon, Jundong Yu, Sung-tae Yee, Young Hwan Ahn, Gwang Lee, Su-il Seong, Man-jeong Paik

“…Organic acid (OA) profiling analysis was performed in culture media from Lactobacillus pentosus K34 (L. pentosusK34) and Pediococcus lolli PL24 (P. lolli PL24)…”
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Tetrahydropteridines possess antioxidant roles to guard against glucose-induced oxidative stress in Dictyostelium discoideum by Park, Seon-Ok, Kim, Hye-Lim, Lee, Soo-Woong, Park, Young Shik

“…Glucose effects on the vegetative growth of Dictyostelium discoideum Ax2 were studied by examining oxidative stress and tetrahydropteridine synthesis in cells…”
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Fermented soy bean extract suppresses differentiation of 3T3-L1 preadipocytes and facilitates its glucose utilization by Hwang, Ji Won, Do, Hyun Ju, Kim, Oh Yoen, Chung, Ji Hyung, Lee, Jae-Yeon, Park, Young Shik, Hwang, Kyo Yeol, Seong, Su-Il, Shin, Min-Jeong

“…•Fermented soy bean extract reduced lipid accumulation by suppressing the differentiation of 3T3-L1 adipocytes.•Fermented soy bean extract improved glucose…”
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Assessment of antidiabetogenic potential of fermented soybean extracts in streptozotocin-induced diabetic rat by Lim, Kyu Hee, Han, Ji-Hui, Lee, Jae Yeon, Park, Young Shik, Cho, Yong Seok, Kang, Kyung-Don, Yuk, Won Jeong, Hwang, Kyo Yeol, Seong, Su-Il, Kim, Bumseok, Kwon, JungKee, Kang, Chang-Won, Kim, Jong-Hoon

“…► We isolated Bacillus subtilis MORI-fermented soybean extracts (BTD-1). ► BTD-1 decreased the glucose level via the increment of insulin in diabetic rat. ►…”
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Anti-diabetic Effect of the Soybean Extract Fermented by Bacillus subtilis MORI in db/db Mice by Nam, Hajin, Jung, Harry, Karuppasamy, S, Park, Young Shik, Cho, Yong Seok, Lee, Jae Yeon, Seong, Su-Il, Suh, Jun Gyo

“…This study investigated the effects of soy bean extract fermented by Bacillus subtilis MORI (BTD-1) on blood glucose, hemoglobin A1c (HbA1c), plasma insulin,…”
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Quantitative analysis by flow cytometry of green fluorescent protein-tagged human phenylalanine hydroxylase expressed in Dictyostelium by Kim Hye-Lim, Ryu Hyun-Chul, Park Young Shik

“…We have developed a fluorescence assay system to monitor the protein levels of human phenylalanine hydroxylase (hPAH). Wild-type (WT) and three mutant hPAHs…”
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Role of Cyanopterin in UV/Blue Light Signal Transduction of Cyanobacterium Synechocystis sp. PCC 6803 Phototaxis by Moon, Yoon-Jung, Lee, Eun-Mi, Park, Young Mok, Park, Young Shik, Chung, Won-Il, Chung, Young-Ho

“…We analyzed the effects of inactivating the pteridine glycosyltransferase gene (pgtA) on the photomovement of the cyanobacterium Synechocystis sp. PCC 6803…”
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Investigation of a potential role for aldose reductase AlrA in tetrahydropteridine synthesis in Dictyostelium discoideum Ax2 by Kim Hye-Lim, Ryu Hyun-Chul, Park Young Shik

“…Dictyostelium discoideum Ax2 is well-known for the synthesis of d-threo-tetrahydrobiopterin (DH4) with a smaller amount of l-erythro-tetrahydrobiopterin (BH4)…”
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A Murine Model for Human Sepiapterin-Reductase Deficiency by Yang, Seungkyoung, Lee, Young Jae, Kim, Jin-Man, Park, Sean, Peris, Joanna, Laipis, Philip, Park, Young Shik, Chung, Jae Hoon, Oh, S. Paul

“…Tetrahydrobiopterin (BH 4) is an essential cofactor for several enzymes, including all three forms of nitric oxide synthases, the three aromatic hydroxylases,…”
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Supplementation of a Fermented Soybean Extract Reduces Body Mass and Prevents Obesity in High Fat Diet-Induced C57BL/6J Obese Mice by Lee, Jae Yeon, Aravinthan, Adithan, Park, Young Shik, Hwang, Kyo Yeol, Seong, Su-Il, Hwang, Kwontack

“…Obesity is a growing health problem that many countries face, mostly due to the consumption of a Westernized diet. In this present study we observed the…”
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Molecular Cloning of Cyanobacterial Pteridine Glycosyltransferases That Catalyze the Transfer of either Glucose or Xylose to Tetrahydrobiopterin by Lee, Yeol Gyun, Kim, Ae Hyun, Park, Mi Bi, Kim, Hye-Lim, Lee, Kon Ho, Park, Young Shik

“…Here, we report cloning of cyanobacterial genes encoding pteridine glycosyltransferases that catalyze glucosyl or xylosyl transfer from UDP-sugars to…”
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Identification of the genes encoding enzymes involved in the early biosynthetic pathway of pteridines in Synechocystis sp. PCC 6803 by Woong Lee, Soo, Woo Lee, Hee, Jae Chung, Hyun, Kim, Young-A., Jeong Kim, Yeon, Hahn, Yoonsoo, Hoon Chung, Jae, Shik Park, Young

“…Abstract The biosynthetic pathway for the pteridine moiety of cyanopterine, as well as tetrahydrobiopterine, has been investigated in Synechocystis sp. PCC…”
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Anti-diabetic effect of the soybean extract fermented by Bacillus subtilis MORI in db/db mice by Nam, Hajin, Jung, Harry, Karuppasamy, S., Park, Young Shik, Cho, Yong Seok, Lee, Jae Yeon, Seong, Su-Il, Suh, Jun Gyo

“…This study investigated the effects of soy bean extract fermented by Bacillus subtilis MORI (BTD-1) on blood glucose, hemoglobin A1c (HbA1c), plasma insulin,…”
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