Search Results - "Park, Young N."
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Data set for the reporting of intrahepatic cholangiocarcinoma, perihilar cholangiocarcinoma and hepatocellular carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR)
Published in Histopathology (01-09-2018)“…Optimal patient management benefits from comprehensive and accurate pathology reports that contribute to cancer staging and prognostication. Proforma reports…”
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2
CRISPR knockout screen implicates three genes in lysosome function
Published in Scientific reports (03-07-2019)“…Defective biosynthesis of the phospholipid PI(3,5)P 2 underlies neurological disorders characterized by cytoplasmic accumulation of large lysosome-derived…”
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3
A model organism pipeline provides insight into the clinical heterogeneity of TARS1 loss-of-function variants
Published in HGG advances (18-07-2024)“…Aminoacyl-tRNA synthetases (ARSs) are ubiquitously expressed, essential enzymes that complete the first step of protein translation: ligation of amino acids to…”
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4
Clinicopathologic and MRI features of combined hepatocellular‐cholangiocarcinoma in patients with or without cirrhosis
Published in Liver international (01-07-2021)“…Background and Aims Differences in combined hepatocellular‐cholangiocarcinomas (cHCC‐CCAs) arising in high‐risk patients with or without liver cirrhosis have…”
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5
Biallelic loss-of-function variants of SLC12A9 cause lysosome dysfunction and a syndromic neurodevelopmental disorder
Published in Genetics in medicine (01-05-2024)“…Pathogenic variants of FIG4 generate enlarged lysosomes and neurological and developmental disorders. To identify additional genes regulating lysosomal volume,…”
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TPRG1‐AS1 induces RBM24 expression and inhibits liver cancer progression by sponging miR‐4691‐5p and miR‐3659
Published in Liver international (01-11-2021)“…Background & Aims Noncoding RNAs (ncRNAs) play critical roles in hepatocellular carcinoma (HCC) progression. Here, by performing RNA‐sequencing (RNA‐Seq)…”
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Severe acute liver disease in adults: Contemporary role of histopathology
Published in Histopathology (01-10-2024)“…Liver biopsies have consistently contributed to our understanding of the pathogenesis and aetiologies of acute liver disease. As other diagnostic modalities…”
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8
Early on-treatment change in liver stiffness predicts development of liver-related events in chronic hepatitis B patients receiving antiviral therapy
Published in Liver international (01-02-2013)“…Backgrounds/Aims Monitoring fibrosis is mandatory for detailed prognostification in patients with chronic liver disease. We developed optimized cut‐offs for…”
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Predictive factors for long-term survival in patients with clinically significant portal hypertension following resection of hepatocellular carcinoma
Published in Liver international (01-04-2011)“…Background: Hepatic resection for hepatocellular carcinoma (HCC) is not currently recommended for patients with clinically significant portal hypertension…”
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10
Serum markers for necroinflammatory activity in patients with chronic viral hepatitis and normal or mildly elevated aminotransferase levels
Published in Liver international (01-10-2011)“…Background: Reports on the usefulness of serum markers for predicting liver necroinflammation are limited. The aim of this study was to determine the serum…”
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Pathological predictive factors for late recurrence of hepatocellular carcinoma in chronic liver disease
Published in Liver international (01-07-2021)“…Background & Aims Late recurrence of hepatocellular carcinoma (HCC) is regarded as de novo HCC from chronic hepatitis. This study investigated…”
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Mannosylated polyethylenimine coupled mesoporous silica nanoparticles for receptor-mediated gene delivery
Published in International journal of pharmaceutics (09-07-2008)“…Organic–inorganic nanohybrids have been studied for their use as non-viral transfection agents. The purpose of this study was to examine the ability of…”
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Increased expression of stathmin and elongation factor 1α in precancerous nodules with telomere dysfunction in hepatitis B viral cirrhotic patients
Published in Journal of translational medicine (31-05-2014)“…Telomere dysfunction is important in carcinogenesis, and recently, stathmin and elongation factor 1α (EF1α) were reported to be up-regulated in telomere…”
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14
Antibacterial activity of chitosans and chitosan oligomers with different molecular weights
Published in International journal of food microbiology (25-03-2002)“…Antibacterial activities of six chitosans and six chitosan oligomers with different molecular weights (Mws) were examined against four gram-negative (…”
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Predictive factors for long-term survival in patients with clinically significant portal hypertension following resection of hepatocellular carcinoma: Predictive factors for long-term survival in patients with clinically significant portal hypertension
Published in Liver international (01-04-2011)Get full text
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Stability and antibacterial activity of chitosan solutions affected by storage temperature and time
Published in Carbohydrate polymers (25-07-2006)“…Stability of chitosan ( M w of 2025 and 1110 kDa) solutions and their antibacterial activity against gram-positive ( Listeria monocytogenes and Staphylococcus…”
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Estrogenic/antiestrogenic activities of a Epimedium koreanum extract and its major components: in vitro and in vivo studies
Published in Food and chemical toxicology (01-08-2012)“…► ICT and quercetin exhibited in vitro ER mediated estrogenic activity with a more potent interaction with ERβ. ► Prenylflavonoid glycosides did not show any…”
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Identification of 2,3,6-trisubstituted quinoxaline derivatives as a Wnt2 /β -catenin pathway inhibitor in non-small-cell lung cancer cell lines
Published in Bioorganic & medicinal chemistry letters (01-10-2010)“…The 1434 small molecules were screened and identified 13 number of the 2,3,6-trisubstituted quinoxaline derivatives(>1 μM) that were able to inhibit the…”
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Electrocardiographic Comparison of Ventricular Arrhythmias in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy and Right Ventricular Outflow Tract Tachycardia
Published in Journal of the American College of Cardiology (16-08-2011)“…Objectives The purpose of this study was to evaluate whether electrocardiographic characteristics of ventricular arrhythmias distinguish patients with…”
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Anti-inflammatory activity of bark of Dioscorea batatas DECNE through the inhibition of iNOS and COX-2 expressions in RAW264.7 cells via NF-κB and ERK1/2 inactivation
Published in Food and chemical toxicology (01-11-2010)“…We identified a bioactive herbal medicine with anti-inflammatory activity from an ethanol extract derived from the bark of Dioscorea batatas DECNE (BDB) in…”
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