Search Results - "Park, Young N."

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    CRISPR knockout screen implicates three genes in lysosome function by Lenk, Guy M., Park, Young N., Lemons, Rosemary, Flynn, Emma, Plank, Margaret, Frei, Christen M., Davis, Michael J., Gregorka, Brian, Swanson, Joel A., Meisler, Miriam H., Kitzman, Jacob O.

    Published in Scientific reports (03-07-2019)
    “…Defective biosynthesis of the phospholipid PI(3,5)P 2 underlies neurological disorders characterized by cytoplasmic accumulation of large lysosome-derived…”
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    A model organism pipeline provides insight into the clinical heterogeneity of TARS1 loss-of-function variants by Meyer-Schuman, Rebecca, Cale, Allison R., Pierluissi, Jennifer A., Jonatzke, Kira E., Park, Young N., Lenk, Guy M., Oprescu, Stephanie N., Grachtchouk, Marina A., Dlugosz, Andrzej A., Beg, Asim A., Meisler, Miriam H., Antonellis, Anthony

    Published in HGG advances (18-07-2024)
    “…Aminoacyl-tRNA synthetases (ARSs) are ubiquitously expressed, essential enzymes that complete the first step of protein translation: ligation of amino acids to…”
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    Clinicopathologic and MRI features of combined hepatocellular‐cholangiocarcinoma in patients with or without cirrhosis by Yoon, Jongjin, Hwang, Jeong A., Lee, Sunyoung, Lee, Ji E., Ha, Sang Y., Park, Young N.

    Published in Liver international (01-07-2021)
    “…Background and Aims Differences in combined hepatocellular‐cholangiocarcinomas (cHCC‐CCAs) arising in high‐risk patients with or without liver cirrhosis have…”
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    TPRG1‐AS1 induces RBM24 expression and inhibits liver cancer progression by sponging miR‐4691‐5p and miR‐3659 by Choi, Ji‐Hye, Kwon, So M., Moon, Sung U., Yoon, Sarah, Shah, Masaud, Lee, Byoung G., Yang, Jieun, Park, Young N., Wang, Hee‐Jung, Woo, Hyun G.

    Published in Liver international (01-11-2021)
    “…Background & Aims Noncoding RNAs (ncRNAs) play critical roles in hepatocellular carcinoma (HCC) progression. Here, by performing RNA‐sequencing (RNA‐Seq)…”
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    Early on-treatment change in liver stiffness predicts development of liver-related events in chronic hepatitis B patients receiving antiviral therapy by Kim, Beom K., Oh, Hyun J., Park, Jun Y., Kim, Do Y., Ahn, Sang H., Han, Kwang H., Park, Yehyun, J. Yoo, Eun, Park, Young N., Kim, Seung U.

    Published in Liver international (01-02-2013)
    “…Backgrounds/Aims Monitoring fibrosis is mandatory for detailed prognostification in patients with chronic liver disease. We developed optimized cut‐offs for…”
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    Predictive factors for long-term survival in patients with clinically significant portal hypertension following resection of hepatocellular carcinoma by Choi, Gi H., Park, Jun Y., Hwang, Ho K., Kim, Dong H., Kang, Chang M., Choi, Jin S., Park, Young N., Kim, Do Y., Ahn, Sang H., Han, Kwang-Hyub, Chon, Chae Y., Lee, Woo J.

    Published in Liver international (01-04-2011)
    “…Background: Hepatic resection for hepatocellular carcinoma (HCC) is not currently recommended for patients with clinically significant portal hypertension…”
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    Serum markers for necroinflammatory activity in patients with chronic viral hepatitis and normal or mildly elevated aminotransferase levels by Cheong, Jae Y., Kim, Dong J., Hwang, Seong G., Yang, Jin M., Kim, Young B., Park, Young N., Cho, Sung W.

    Published in Liver international (01-10-2011)
    “…Background: Reports on the usefulness of serum markers for predicting liver necroinflammation are limited. The aim of this study was to determine the serum…”
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    Pathological predictive factors for late recurrence of hepatocellular carcinoma in chronic liver disease by Nahm, Ji Hae, Lee, Hye Sun, Kim, Haeryoung, Yim, Sun Young, Shin, Ji‐hyun, Yoo, Jeong Eun, Ahn, Sang Hoon, Choi, Jin Sub, Lee, Ju‐Seog, Park, Young Nyun

    Published in Liver international (01-07-2021)
    “…Background & Aims Late recurrence of hepatocellular carcinoma (HCC) is regarded as de novo HCC from chronic hepatitis. This study investigated…”
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    Mannosylated polyethylenimine coupled mesoporous silica nanoparticles for receptor-mediated gene delivery by Park, In Young, Kim, In Yong, Yoo, Mi Kyong, Choi, Yun Jaie, Cho, Myung-Haing, Cho, Chong Su

    Published in International journal of pharmaceutics (09-07-2008)
    “…Organic–inorganic nanohybrids have been studied for their use as non-viral transfection agents. The purpose of this study was to examine the ability of…”
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    Increased expression of stathmin and elongation factor 1α in precancerous nodules with telomere dysfunction in hepatitis B viral cirrhotic patients by Ahn, Ei Yong, Yoo, Jeong Eun, Rhee, Hyungjin, Kim, Myung Soo, Choi, Junjeong, Ko, Jung Eun, Lee, Jee San, Park, Young Nyun

    Published in Journal of translational medicine (31-05-2014)
    “…Telomere dysfunction is important in carcinogenesis, and recently, stathmin and elongation factor 1α (EF1α) were reported to be up-regulated in telomere…”
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    Antibacterial activity of chitosans and chitosan oligomers with different molecular weights by No, Hong Kyoon, Young Park, Na, Ho Lee, Shin, Meyers, Samuel P

    Published in International journal of food microbiology (25-03-2002)
    “…Antibacterial activities of six chitosans and six chitosan oligomers with different molecular weights (Mws) were examined against four gram-negative (…”
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    Stability and antibacterial activity of chitosan solutions affected by storage temperature and time by No, Hong Kyoon, Kim, Su Hyun, Lee, Shin Ho, Park, Na Young, Prinyawiwatkul, Witoon

    Published in Carbohydrate polymers (25-07-2006)
    “…Stability of chitosan ( M w of 2025 and 1110 kDa) solutions and their antibacterial activity against gram-positive ( Listeria monocytogenes and Staphylococcus…”
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    Estrogenic/antiestrogenic activities of a Epimedium koreanum extract and its major components: in vitro and in vivo studies by Kang, Hyun Ku, Choi, Yun-Ho, Kwon, Hyosuk, Lee, Sang-Bum, Kim, Dong-Hyun, Sung, Chung Ki, Park, Young In, Dong, Mi-Sook

    Published in Food and chemical toxicology (01-08-2012)
    “…► ICT and quercetin exhibited in vitro ER mediated estrogenic activity with a more potent interaction with ERβ. ► Prenylflavonoid glycosides did not show any…”
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    Identification of 2,3,6-trisubstituted quinoxaline derivatives as a Wnt2 /β -catenin pathway inhibitor in non-small-cell lung cancer cell lines by Lee, Sang-Bum, Park, Young In, Dong, Mi-Sook, Gong, Young-Dae

    Published in Bioorganic & medicinal chemistry letters (01-10-2010)
    “…The 1434 small molecules were screened and identified 13 number of the 2,3,6-trisubstituted quinoxaline derivatives(>1 μM) that were able to inhibit the…”
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