Search Results - "Park, Wei Sun"

Cooperative Activation of PI3K by Ras and Rho Family Small GTPases by Yang, Hee Won, Shin, Min-Gyoung, Lee, Sangkyu, Kim, Jeong-Rae, Park, Wei Sun, Cho, Kwang-Hyun, Meyer, Tobias, Do Heo, Won

“…Phosphoinositide 3-kinases (PI3Ks) and Ras and Rho family small GTPases are key regulators of cell polarization, motility, and chemotaxis. They influence each…”
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PI(3,4,5)P₃ and PI(4,5)P₂ Lipids Target Proteins with Polybasic Clusters to the Plasma Membrane by Heo, Won Do, Inoue, Takanari, Park, Wei Sun, Kim, Man Lyang, Park, Byung Ouk, Wandless, Thomas J, Meyer, Tobias

“…Many signaling, cytoskeletal, and transport proteins have to be localized to the plasma membrane (PM) in order to carry out their function. We surveyed…”
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High-fidelity optical diffraction tomography of live organisms using iodixanol refractive index matching by Lee, Dohyeon, Lee, Moosung, Kwak, Haechan, Kim, Young Seo, Shim, Jaehyu, Jung, Jik Han, Park, Wei-Sun, Park, Ji-Ho, Lee, Sumin, Park, YongKeun

“…Optical diffraction tomography (ODT) enables the three-dimensional (3D) refractive index (RI) reconstruction. However, when the RI difference between a sample…”
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Mechanistic Basis of Differential Cellular Responses of Phosphatidylinositol 3,4-Bisphosphate- and Phosphatidylinositol 3,4,5-Trisphosphate-binding Pleckstrin Homology Domains by Manna, Debasis, Albanese, Alexandra, Park, Wei Sun, Cho, Wonhwa

“…Phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) are lipid second messengers that regulate…”
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Label-free multiplexed microtomography of endogenous subcellular dynamics using generalizable deep learning by Jo, YoungJu, Cho, Hyungjoo, Park, Wei Sun, Kim, Geon, Ryu, DongHun, Kim, Young Seo, Lee, Moosung, Park, Sangwoo, Lee, Mahn Jae, Joo, Hosung, Jo, HangHun, Lee, Seongsoo, Lee, Sumin, Min, Hyun-seok, Heo, Won Do, Park, YongKeun

“…Simultaneous imaging of various facets of intact biological systems across multiple spatiotemporal scales is a long-standing goal in biology and medicine, for…”
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Correlative three-dimensional fluorescence and refractive index tomography: bridging the gap between molecular specificity and quantitative bioimaging by Kim, Kyoohyun, Park, Wei Sun, Na, Sangchan, Kim, Sangbum, Kim, Taehong, Heo, Won Do, Park, YongKeun

“…Optical diffraction tomography (ODT) provides label-free three-dimensional (3D) refractive index (RI) measurement of biological samples. However, due to the…”
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Salmonella exploits host Rho GTPase signalling pathways through the phosphatase activity of SopB by Truong, Dorothy, Boddy, Kirsten C., Canadien, Veronica, Brabant, Danielle, Fairn, Gregory D., D'Costa, Vanessa M., Coyaud, Etienne, Raught, Brian, Pérez‐Sala, Dolores, Park, Wei Sun, Heo, Won Do, Grinstein, Sergio, Brumell, John H.

“…Salmonella uses Type 3 secretion systems (T3SSs) to deliver virulence factors, called effectors, into host cells during infection. The T3SS effectors promote…”
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Comprehensive Identification of PIP3-Regulated PH Domains from C. elegans to H. sapiens by Model Prediction and Live Imaging by Park, Wei Sun, Do Heo, Won, Whalen, James H., O'Rourke, Nancy A., Bryan, Heather M., Meyer, Tobias, Teruel, Mary N.

“…Phosphoinositide 3-kinase (PI3K) and its product phosphatidylinositol(3,4,5)-trisphosphate (PIP3) control cell growth, migration, and other processes by…”
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VipD of Legionella pneumophila targets activated Rab5 and Rab22 to interfere with endosomal trafficking in macrophages by Ku, Bonsu, Lee, Kwang-Hoon, Park, Wei Sun, Yang, Chul-Su, Ge, Jianning, Lee, Seong-Gyu, Cha, Sun-Shin, Shao, Feng, Heo, Won Do, Jung, Jae U, Oh, Byung-Ha

“…Upon phagocytosis, Legionella pneumophila translocates numerous effector proteins into host cells to perturb cellular metabolism and immunity, ultimately…”
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Endocytic Rab proteins are required for hepatitis C virus replication complex formation by Manna, David, Aligo, Jason, Xu, Chenjia, Park, Wei Sun, Koc, Hasan, Do Heo, Won, Konan, Kouacou V

“…Abstract During infection, hepatitis C virus (HCV) NS4B protein remodels host membranes to form HCV replication complexes (RC) which appear as foci under…”
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Phosphoinositides Differentially Regulate Protrudin Localization through the FYVE Domain by Gil, Jung-Eun, Kim, Eui, Kim, Il-Shin, Ku, Bonsu, Park, Wei Sun, Oh, Byung-Ha, Ryu, Sung Ho, Cho, Wonhwa, Heo, Won Do

“…Protrudin is a FYVE (Fab 1, YOTB, Vac 1, and EEA1) domain-containing protein involved in transport of neuronal cargoes and implicated in the onset of…”
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Lpg0393 of Legionella pneumophila is a guanine-nucleotide exchange factor for Rab5, Rab21 and Rab22 by Sohn, Young-Sik, Shin, Ho-Chul, Park, Wei Sun, Ge, Jianning, Kim, Chan-Hee, Lee, Bok Luel, Heo, Won Do, Jung, Jae U, Rigden, Daniel John, Oh, Byung-Ha

“…Legionella pneumophila, a human intracellular pathogen, encodes about 290 effector proteins that are translocated into host cells through a secretion…”
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STIM2 Is a Feedback Regulator that Stabilizes Basal Cytosolic and Endoplasmic Reticulum Ca2+ Levels by Brandman, Onn, Liou, Jen, Park, Wei Sun, Meyer, Tobias

“…Deviations in basal Ca2+ levels interfere with receptor-mediated Ca2+ signaling as well as endoplasmic reticulum (ER) and mitochondrial function. While…”
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PI(3,4,5)P 3 and PI(4,5)P 2 Lipids Target Proteins with Polybasic Clusters to the Plasma Membrane by Heo, Won Do, Inoue, Takanari, Park, Wei Sun, Kim, Man Lyang, Park, Byung Ouk, Wandless, Thomas J., Meyer, Tobias

“…Many signaling, cytoskeletal, and transport proteins have to be localized to the plasma membrane (PM) in order to carry out their function. We surveyed…”
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The Alliance for Cellular Signaling Plasmid Collection by Zavzavadjian, Joelle R., Couture, Sam, Park, Wei Sun, Whalen, James, Lyon, Stephen, Lee, Genie, Fung, Eileen, Mi, Qingli, Liu, Jamie, Wall, Estelle, Santat, Leah, Dhandapani, Kavitha, Kivork, Christine, Driver, Adrienne, Zhu, Xiaocui, Chang, Mi Sook, Randhawa, Baljinder, Gehrig, Elizabeth, Bryan, Heather, Verghese, Mary, Maer, Andreia, Saunders, Brian, Ning, Yuhong, Subramaniam, Shankar, Meyer, Tobias, Simon, Melvin I., O’Rourke, Nancy, Chandy, Grischa, Fraser, Iain D.C.

“…Cellular responses to inputs that vary both temporally and spatially are determined by complex relationships between the components of cell signaling networks…”
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Release of Infectious Hepatitis C Virus from Huh7 Cells Occurs via a trans-Golgi Network-to-Endosome Pathway Independent of Very-Low-Density Lipoprotein Secretion by Mankouri, Jamel, Walter, Cheryl, Stewart, Hazel, Bentham, Matthew, Park, Wei Sun, Heo, Won Do, Fukuda, Mitsunori, Griffin, Stephen, Harris, Mark

“…The release of infectious hepatitis C virus (HCV) particles from infected cells remains poorly characterized. We previously demonstrated that virus release is…”
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Abstract 2530: Advancing ICK assay: Real-time, label-free imaging of lymphocyte subsets by Oh, Sanggeun, Do, Jaephil, Min, Hyun-Seok, Ryu, Dongmin, Park, Wei sun

“…Abstract Background: Immune Cell Killing (ICK) Assay is pivotal in immunology and clinical research, uncovering the intricate connections between the immune…”
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PLEKHG3 enhances polarized cell migration by activating actin filaments at the cell front by Nguyen, Trang Thi Thu, Park, Wei Sun, Park, Byung Ouk, Kim, Cha Yeon, Oh, Yohan, Kim, Jin Man, Choi, Hana, Kyung, Taeyoon, Kim, Cheol-Hee, Lee, Gabsang, Hahn, Klaus M., Meyer, Tobias, Heo, Won Do

“…Cells migrate by directing Ras-related C3 botulinum toxin substrate 1 (Rac1) and cell division control protein 42 (Cdc42) activities and by polymerizing actin…”
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Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning by Yoon, Jonghee, Jo, YoungJu, Kim, Young Seo, Yu, Yeongjin, Park, Jiyeon, Lee, Sumin, Park, Wei Sun, Park, YongKeun

“…We describe here a protocol for the label-free identification of lymphocyte subtypes using quantitative phase imaging and machine learning. Identification of…”
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Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning by Yoon, Jonghee, Jo, YoungJu, Kim, Young Seo, Yu, Yeongjin, Park, Jiyeon, Lee, Sumin, Park, Wei Sun, Park, YongKeun

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