Search Results - "Park, Tae Kwann"
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1
Low-Fluence Photodynamic Therapy versus Ranibizumab for Chronic Central Serous Chorioretinopathy
Published in Ophthalmology (Rochester, Minn.) (01-02-2014)“…Purpose To compare the efficacy and safety between low-fluence photodynamic therapy (PDT) and the intravitreal ranibizumab in the treatment of chronic central…”
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2
Intranasal delivery of the cytoplasmic domain of CTLA-4 using a novel protein transduction domain prevents allergic inflammation
Published in Nature medicine (01-05-2006)“…CTLA-4 is a negative regulator of T-cell activation, and its inhibitory effects can be accomplished either by competition with CD28 or by transmitting negative…”
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3
Association between Open-Angle Glaucoma and the Risks of Alzheimer’s and Parkinson’s Diseases in South Korea: A 10-year Nationwide Cohort Study
Published in Scientific reports (24-07-2018)“…We aimed to investigate the risks of Alzheimer’s (AD) and Parkinson’s disease (PD) in the 10 years following diagnosis of open-angle glaucoma (OAG) using a…”
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4
mTOR-dependent dysregulation of autophagy contributes to the retinal ganglion cell loss in streptozotocin-induced diabetic retinopathy
Published in Cell communication and signaling (26-02-2021)“…Neurodegeneration, an early event in the pathogenesis of diabetic retinopathy (DR), precedes clinically detectable microvascular damage. Autophagy…”
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5
The time course of visual field recovery and changes of retinal ganglion cells after optic chiasmal decompression
Published in Investigative ophthalmology & visual science (10-10-2011)“…To investigate the time course of visual field recovery and changes of retinal ganglion cells (RGCs) after chiasmal decompression using standard automated…”
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6
Characterization of the role of autophagy in retinal ganglion cell survival over time using a rat model of chronic ocular hypertension
Published in Scientific reports (11-03-2021)“…Autophagy is an essential cellular process for the degradation and recycling of cellular components, and its dysregulation has been linked to neuronal cell…”
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7
Association between chronic kidney disease and open-angle glaucoma in South Korea: a 12-year nationwide retrospective cohort study
Published in Scientific reports (01-03-2022)“…Various non-intraocular pressure factors have been identified as possible risk factors for open-angle glaucoma (OAG). However, there is still controversy…”
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8
Visual prognostic value of optical coherence tomography and photopic negative response in chiasmal compression
Published in Investigative ophthalmology & visual science (31-10-2011)“…To investigate the potential of the optical coherence tomography (OCT) measurement of retinal nerve fiber layer (RNFL) thickness and ganglion cell complex…”
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9
Proteome alterations in the aqueous humor reflect structural and functional phenotypes in patients with advanced normal-tension glaucoma
Published in Scientific reports (24-01-2022)“…Previous reports have shown possible association between altered protein levels in aqueous humor (AH) and normal-tension glaucoma (NTG), but the underlying…”
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10
Early Developmental Characteristics and Features of a Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis
Published in International journal of molecular sciences (01-08-2024)“…X-linked juvenile retinoschisis (XLRS) is a hereditary retinal degeneration affecting young males caused by mutations in the retinoschisin ( ) gene. We…”
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11
Development of Non-Invasive miRNA Markers for Assessing the Quality of Human Induced Pluripotent Stem Cell-Derived Retinal Organoids
Published in International journal of molecular sciences (01-08-2024)“…Human retinal organoids (ROs) have emerged as valuable tools for studying retinal development, modeling human retinal diseases, and screening drugs. However,…”
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12
Suppression of choroidal neovascularization and epithelial-mesenchymal transition in retinal pigmented epithelium by adeno-associated virus-mediated overexpression of CCN5 in mice
Published in PloS one (13-06-2022)“…Choroidal neovascularization (CNV) is a defining characteristic feature of neovascular age-related macular degeneration (nAMD) that frequently results in…”
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13
Mature cataract and lens-induced glaucoma associated with an asymptomatic intralenticular foreign body
Published in Journal of cataract and refractive surgery (01-03-2007)“…We report a case of mature cataract and lens-induced glaucoma associated with an asymptomatic intralenticular foreign body. At initial presentation, the…”
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14
Intravitreal Administration of Retinal Organoids-Derived Exosomes Alleviates Photoreceptor Degeneration in Royal College of Surgeons Rats by Targeting the Mitogen-Activated Protein Kinase Pathway
Published in International journal of molecular sciences (27-07-2023)“…Increasing evidence suggests that exosomes are involved in retinal cell degeneration, including their insufficient release; hence, they have become important…”
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15
Impact of ibrutinib on inflammation in a mouse model of Graves' orbitopathy
Published in Frontiers in endocrinology (Lausanne) (30-08-2024)“…Bruton's tyrosine kinase (BTK) and interleukin (IL)-2 Inducible T-cell Kinase (ITK) inhibitors have anti-inflammatory properties. We investigated the…”
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16
Anti-Human VEGF Repebody Effectively Suppresses Choroidal Neovascularization and Vascular Leakage
Published in PloS one (25-03-2016)“…Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness among people over the age of 60. Vascular endothelial growth factor…”
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17
A Randomized Pilot Study of Low-Fluence Photodynamic Therapy Versus Intravitreal Ranibizumab for Chronic Central Serous Chorioretinopathy
Published in American journal of ophthalmology (01-11-2011)“…Purpose To report 6-month outcomes of a prospective, randomized study comparing the efficacy and safety between low-fluence photodynamic therapy (PDT) and…”
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18
Preferential Hyperacuity Perimeter and Prognostic Factors for Metamorphopsia After Idiopathic Epiretinal Membrane Surgery
Published in American journal of ophthalmology (2013)“…Purpose To document changes in metamorphopsia via preferential hyperacuity perimeter and to identify prognostic factors related to favorable metamorphopsia…”
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19
Clinical Manifestations and Genetic Analysis of 5 Korean Choroideremia Patients Initially Diagnosed With Retinitis Pigmentosa
Published in Journal of Korean medical science (17-01-2022)“…To investigate the clinical findings of choroideremia patients and perform genetic analysis by whole-exome sequencing (WES). A total of 94 patients initially…”
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20
mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV
Published in Cell communication and signaling (14-06-2019)“…The mechanistic target of rapamycin (mTOR) pathway is a potential target to inhibit pathologic processes in choroidal neovascularization. However, the exact…”
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