Search Results - "Park, Su Chan"

Branching annihilating random walk with long-range repulsion: logarithmic scaling, reentrant phase transitions, and crossover behaviors by Park, Su-Chan

“…We study absorbing phase transitions in the one-dimensional branching annihilating random walk with long-range repulsion. The repulsion is implemented as…”
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Recombination and mutational robustness in neutral fitness landscapes by Klug, Alexander, Park, Su-Chan, Krug, Joachim

“…Mutational robustness quantifies the effect of random mutations on fitness. When mutational robustness is high, most mutations do not change fitness or have…”
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Clonal interference in large populations by Park, Su-Chan, Krug, Joachim

“…Clonal interference, the competition between lineages arising from different beneficial mutations in an asexually reproducing population, is an important…”
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EVOLUTIONARY ADVANTAGE OF SMALL POPULATIONS ON COMPLEX FITNESS LANDSCAPES by Jain, Kavita, Krug, Joachim, Park, Su-Chan

“…Recent experimental and theoretical studies have shown that small asexual populations evolving on complex fitness landscapes may achieve a higher fitness than…”
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Rare beneficial mutations cannot halt Muller's ratchet in spatial populations by Park, Su-Chan, Klatt, Philipp, Krug, Joachim

“…Muller's ratchet describes the irreversible accumulation of deleterious mutations in asexual populations. In well-mixed populations the speed of fitness…”
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Induction of antigen-specific immune tolerance using biodegradable nanoparticles containing antigen and dexamethasone by Kim, Sang-Hyun, Moon, Jun-Hyeok, Jeong, Seong-Un, Jung, Ho-Hyun, Park, Chan-Su, Hwang, Bang Yeon, Lee, Chong-Kil

“…Dexamethasone (Dex) has long been used as a potent immunosuppressive agent in the treatment of inflammatory and autoimmune diseases, despite serious side…”
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Tolerogenic dendritic cells are efficiently generated using minocycline and dexamethasone by Lee, Jae-Hee, Park, Chan-Su, Jang, Sundong, Kim, Ji-Wan, Kim, Sang-Hyeon, Song, Sukgil, Kim, Kyungjae, Lee, Chong-Kil

“…Tolerogenic dendritic cells (tDCs) represent a promising tool for cellular therapy against autoimmune diseases, allergies, and transplantation rejection…”
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The Speed of Evolution in Large Asexual Populations by Park, Su-Chan, Simon, Damien, Krug, Joachim

“…We consider an asexual biological population of constant size N evolving in discrete time under the influence of selection and mutation. Beneficial mutations…”
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Exploring the Effect of Sex on Empirical Fitness Landscapes by de Visser, J. Arjan G. M., Park, Su‐Chan, Krug, Joachim

“…The nature of epistasis has important consequences for the evolutionary significance of sex and recombination. Recent efforts to find negative epistasis as a…”
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H2-O deficiency promotes regulatory T cell differentiation and CD4 T cell hyperactivity by Welsh, Robin A, Song, Nianbin, Park, Chan-Su, Peske, J David, Sadegh-Nasseri, Scheherazade

“…Regulatory T cells (Treg) are crucial immune modulators, yet the exact mechanism of thymic Treg development remains controversial. Here, we present the first…”
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Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self by Geiger, Kristina M., Manoharan, Michael, Coombs, Rachel, Arana, Kathya, Park, Chan-Su, Lee, Angus Y., Shastri, Nilabh, Robey, Ellen A., Coscoy, Laurent

“…The endoplasmic reticulum aminopeptidase associated with antigen processing (ERAAP) plays a crucial role in shaping the peptide-major histocompatibility…”
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Therapeutic efficacy and mechanism of solubilized sturgeon oil in a mouse model of house dust mite-induced atopic dermatitis by Lee, Hee-Sung, Lee, Yong-Kwang, Park, Ji-Hyun, Kim, Sang-Hyun, Park, Chan-Su, Kim, Kyungjae, Lee, Chong-Kil

“…[Display omitted] •Solubilized sturgeon oil (SSO) was prepared from Siberian sturgeon Acipenser baerii.•SSO exerts therapeutic activity on atopic dermatitis…”
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Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells by Park, Chan-Su, Guan, Jian, Rhee, Peter, Gonzalez, Federico, Lee, Hee-Sung, Park, Ji-Hyun, Coscoy, Laurent, Robey, Ellen A, Shastri, Nilabh, Sadegh-Nasseri, Scheherazade

“…The fate of developing T cells is determined by the strength of T cell receptor (TCR) signal they receive in the thymus. This process is finely regulated…”
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Prevention of azoxymethane/dextran sodium sulfate-induced mouse colon carcinogenesis by processed Aloe vera gel by Im, Sun-A, Kim, Ji-Wan, Kim, Hee-Suk, Park, Chan-Su, Shin, Eunju, Do, Seon-Gil, Park, Young In, Lee, Chong-Kil

“…The preventive effect of a processed Aloe vera gel (PAG) on colon carcinogenesis was examined using an azoxymethane (AOM)-initiated and dextran sodium sulfate…”
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High-precision estimate of the critical exponents for the directed Ising universality class by Park, Su-Chan

“…With extensive Monte Carlo simulations, we present high-precision estimates of the critical exponents of branching annihilating random walks with two…”
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Dynamic correlation between intrahost HIV-1 quasispecies evolution and disease progression by Lee, Ha Youn, Perelson, Alan S, Park, Su-Chan, Leitner, Thomas

“…Quantifying the dynamics of intrahost HIV-1 sequence evolution is one means of uncovering information about the interaction between HIV-1 and the host immune…”
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Efficient Anti-Tumor Immunotherapy Using Tumor Epitope-Coated Biodegradable Nanoparticles Combined With Polyinosinic-Polycytidylic Acid and an Anti-PD1 Monoclonal Antibody by Kim, Sang-Hyun, Park, Ji-Hyun, Lee, Sun-Jae, Lee, Hee-Sung, Jung, Jae-Kyung, Lee, Young-Ran, Cho, Hyun-Il, Kim, Jeong-Ki, Kim, Kyungjae, Park, Chan-Su, Lee, Chong-Kil

“…Vaccination with tumor peptide epitopes associated with MHC class I molecules is an attractive approach directed at inducing tumor-specific CTLs. However,…”
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Genotypic Complexity of Fisher's Geometric Model by Hwang, Sungmin, Park, Su-Chan, Krug, Joachim

“…Fisher's geometric model was originally introduced to argue that complex adaptations must occur in small steps because of pleiotropic constraints. When…”
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Characteristics of the oxygen evolution reaction on synthetic copper - cobalt - oxide electrodes for water electrolysis by Park, Yoo Sei, Park, Chan Su, Kim, Chi Ho, Kim, Yang Do, Park, Sungkyun, Lee, Jae Ho

“…A nano-sized Cu 0.7 Co 2.3 O 4 powder was prepared using a thermal decomposition method to achieve an efficient anode catalyst for an economical water…”
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Branching with Selection and Mutation I: Mutant Fitness of Fréchet Type by Park, Su-Chan, Krug, Joachim, Touzo, Léo, Mörters, Peter

“…We investigate two stochastic models of a growing population with discrete and non-overlapping generations, subject to selection and mutation. In our models…”
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