Search Results - "Park, So–Hyeon"
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Machine learning for predicting hepatitis B or C virus infection in diabetic patients
Published in Scientific reports (06-12-2023)“…Highly prevalent hepatitis B and hepatitis C virus (HBV and HCV) infections have been reported among individuals with diabetes. Given the frequently…”
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Inhibition of ANO1 by Cis - and Trans -Resveratrol and Their Anticancer Activity in Human Prostate Cancer PC-3 Cells
Published in International journal of molecular sciences (07-01-2023)“…Anoctamin1 (ANO1), a calcium-activated chloride channel, is involved in the proliferation, migration, and invasion of various cancer cells including head and…”
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3
Novel positive allosteric modulator of protease‐activated receptor 1 promotes skin wound healing in hairless mice
Published in British journal of pharmacology (01-09-2021)“…Background and Purpose Protease‐activated receptor 1 (PAR1) is a GPCR expressed in several skin cell types, including keratinocyte and dermal fibroblast. PAR1…”
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4
Antioxidant and anti-inflammatory activities of the methanol extract from the bran of the colored wheat, 'Ariheuk'
Published in Applied biological chemistry (01-12-2024)“…In vitro antioxidant and anti-inflammatory activities were investigated using a 70% acidic methanol extract of the colored wheat bran, 'Ariheuk.' Active…”
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Synthesis and Biological Evaluation of a Fused Structure of Indolizine and Pyrrolo[1,2-c]pyrimidine: Identification of Its Potent Anticancer Activity against Liver Cancer Cells
Published in Pharmaceuticals (Basel, Switzerland) (01-11-2022)“…A highly efficient approach to a new indolizine scaffold fused with pyrrolo[1,2-c]pyrimidine was achieved via one-pot three-component coupling followed by an…”
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Anticancer Evaluation of Novel Benzofuran-Indole Hybrids as Epidermal Growth Factor Receptor Inhibitors against Non-Small-Cell Lung Cancer Cells
Published in Pharmaceuticals (Basel, Switzerland) (01-02-2024)“…The epidermal growth factor receptor (EGFR), also known as ErbB1 and HER1, belongs to the receptor tyrosine kinase family. EGFR serves as the primary driver in…”
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Punicalagin Ameliorates Lupus Nephritis via Inhibition of PAR2
Published in International journal of molecular sciences (14-07-2020)“…Lupus nephritis (LN) is the most frequent phenotype in patients with systemic lupus erythematosus (SLE) and has a high rate of progression to end-stage renal…”
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Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition
Published in Cell reports (Cambridge) (19-07-2022)“…As an enveloped virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delivers its viral genome into host cells via fusion of the viral and cell…”
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Diversity-oriented generation and biological evaluation of new chemical scaffolds bearing a 2,2-dimethyl-2H-chromene unit: Discovery of novel potent ANO1 inhibitors
Published in Bioorganic chemistry (01-08-2020)“…[Display omitted] •New chemical space bearing a 2,2-dimethyl-2H-chromene unit was synthesized.•3n is a novel potent ANO1 inhibitor with an IC50 value of 1.23…”
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Systematic Review for the Medical Applications of Meditation in Randomized Controlled Trials
Published in International journal of environmental research and public health (22-01-2022)“…Meditation has been increasingly adapted for healthy populations and participants with diseases. Its beneficial effects are still challenging to determine due…”
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11
Development of a Peptide-Based Nano-Sized Cathepsin B Inhibitor for Anticancer Therapy
Published in Pharmaceutics (01-04-2023)“…Numerous cathepsin B inhibitors have been developed and are under investigation as potential cancer treatments. They have been evaluated for their ability to…”
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Novel ANO1 Inhibitor from Mallotus apelta Extract Exerts Anticancer Activity through Downregulation of ANO1
Published in International journal of molecular sciences (04-09-2020)“…Anoctamin1 (ANO1), a calcium-activated chloride channel, is frequently overexpressed in several cancers, including human prostate cancer and oral squamous cell…”
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13
Curcumol metabolized by rat liver S9 fraction and orally administered in mouse suppressed the proliferation of colon cancer in vitro and in vivo
Published in Food science and biotechnology (01-01-2024)“…Following 3R (reduction, refinement, and replacement) principles, we employed the rat liver S9 fraction to mimic liver metabolism of curcumol having high in…”
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Case report: Generalized lymphatic anomaly of multiple abdominal organs in a young dog
Published in Frontiers in veterinary science (05-05-2023)“…A 9-month-old, female Pomeranian dog presented with vomiting and lethargy. Ultrasonography revealed multilobulated anechoic round shape structures at the…”
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Enhanced Antioxidant and Anticancer Properties of Processed Eucommiae Cortex
Published in Natural product sciences (2019)“…Eucommiae Cortex (EC), bark of Eucommia ulmoides, has been known as a traditional medicine to regulate hypertension and immune system. Because silk of gum in…”
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Expansion of chemical space based on a pyrrolo[1,2-a]pyrazine core: Synthesis and its anticancer activity in prostate cancer and breast cancer cells
Published in European journal of medicinal chemistry (15-02-2020)“…In connection with our continued research to generate new aza-fused heteroaromatic chemical scaffolds, we developed a highly atom-economical three-component…”
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Domino [4 + 2] Annulation Access to Quinone–Indolizine Hybrids: Anticancer N‑Fused Polycycles
Published in Journal of organic chemistry (21-08-2020)“…A highly efficient synthetic route to new quinone–indolizine hybrids was accomplished from quinones and N-substituted pyrrole-2-carboxaldehydes via a domino…”
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Structural basis for the toxic activity of MafB2 from maf genomic island 2 (MGI-2) in N. meningitidis B16B6
Published in Scientific reports (27-02-2023)“…The Maf polymorphic toxin system is involved in conflict between strains found in pathogenic Neisseria species such as Neisseria meningitidis and Neisseria…”
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Dendrite-free Zn anodes enabled by a hierarchical zincophilic TiO2 layer for rechargeable aqueous zinc-ion batteries
Published in Applied surface science (30-12-2022)“…[Display omitted] •Mesoporous TiO2 nanoparticles were synthesized by a facile hydrothermal method.•Hierarchical mesoporous TiO2 layer (hmTO-Zn) enables…”
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Analysis of the longitudinal effects of parents’ negative parenting attitude and adolescents’ social intelligence on problematic smartphone game use
Published in Current psychology (New Brunswick, N.J.) (01-06-2024)“…This study aimed to verify the longitudinal influence of negative parenting attitudes and adolescents’ social intelligence on problematic smartphone game use…”
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