Search Results - "Park, Sean S."
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Stereotactic Body Radiation Therapy for Oligometastatic Prostate Cancer
Published in International journal of radiation oncology, biology, physics (01-06-2016)“…Purpose To review outcomes of patients with oligometastatic prostate cancer (PCa) treated with stereotactic body radiation therapy (SBRT) and to identify…”
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PD-1 Restrains Radiotherapy-Induced Abscopal Effect
Published in Cancer immunology research (01-06-2015)“…We investigated the influence of PD-1 expression on the systemic antitumor response (abscopal effect) induced by stereotactic ablative radiotherapy (SABR) in…”
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Synthesis and evaluation of anti-PD-L1-B11 antibody fragments for PET imaging of PD-L1 in breast cancer and melanoma tumor models
Published in Scientific reports (22-08-2024)“…There is a critical need to non-invasively assess the PD-L1 expression in tumors as a predictive biomarker for determining the efficacy of anti-PD-1/PD-L1…”
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Case Report: Simultaneous Hyperprogression and Fulminant Myocarditis in a Patient With Advanced Melanoma Following Treatment With Immune Checkpoint Inhibitor Therapy
Published in Frontiers in immunology (02-02-2021)“…We report here a patient with stage IV mucosal melanoma treated with dual immune checkpoint inhibitor (ICI) therapy (Nivolumab/Ipilimumab) who experienced…”
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Phase II Evaluation of Stereotactic Ablative Radiotherapy (SABR) and Immunity in 11C-Choline-PET/CT–Identified Oligometastatic Castration-Resistant Prostate Cancer
Published in Clinical cancer research (01-12-2021)“…Abstract Purpose: Outcomes for resistant metastatic castration-resistant prostate cancer (CRPC) are poor. Stereotactic ablative radiotherapy (SABR) induces…”
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Rescuing Cancer Immunity by Plasma Exchange in Metastatic Melanoma (ReCIPE-M1): protocol for a single-institution, open-label safety trial of plasma exchange to clear sPD-L1 for immunotherapy
Published in BMJ open (12-05-2022)“…BackgroundPatients with metastatic melanoma rely on PD-(L)1 immunotherapy, but only one-third of patients experience treatment response and all initial…”
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Stereotactic body radiation therapy in the treatment of oligometastatic prostate cancer
Published in Frontiers in oncology (2013)“…To report outcomes and toxicity for patients with oligometastatic (≤5 lesions) prostate cancer (PCa) treated with stereotactic body radiation therapy (SBRT)…”
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Development and validation of a recursive partitioning analysis–based pretreatment decision‐making tool identifying ideal candidates for spine stereotactic body radiation therapy
Published in Cancer (15-03-2023)“…Background This study was aimed at developing and validating a decision‐making tool predictive of overall survival (OS) for patients receiving stereotactic…”
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Adaptive Image-Guided Radiotherapy (IGRT) Eliminates the Risk of Biochemical Failure Caused by the Bias of Rectal Distension in Prostate Cancer Treatment Planning: Clinical Evidence
Published in International journal of radiation oncology, biology, physics (01-07-2012)“…Purpose Rectal distension has been shown to decrease the probability of biochemical control. Adaptive image-guided radiotherapy (IGRT) corrects for target…”
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Sternum First, Perhaps Pelvis Later
Published in International journal of radiation oncology, biology, physics (01-07-2017)Get full text
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Delineation of Supraclavicular Target Volumes in Breast Cancer Radiation Therapy
Published in International journal of radiation oncology, biology, physics (01-07-2015)“…Purpose To map the location of gross supraclavicular metastases in patients with breast cancer, in order to determine areas at highest risk of harboring…”
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Therapeutic plasma exchange clears circulating soluble PD-L1 and PD-L1-positive extracellular vesicles
Published in Journal for immunotherapy of cancer (01-08-2020)“…BackgroundTrans-acting programmed death-ligand 1 (PD-L1) derives from malignant cells in three known forms. High levels of secreted splice variant PD-L1…”
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3 fraction pencil-beam scanning proton accelerated partial breast irradiation: early provider and patient reported outcomes of a novel regimen
Published in Radiation oncology (London, England) (21-11-2019)“…To report dosimetry and early adverse effects, aesthetic, and patient-reported outcomes of a prospective study of 3-fraction pencil-beam scanning (PBS) proton…”
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Reirradiation for Locoregional Recurrent Breast Cancer
Published in Advances in radiation oncology (01-01-2021)“…Reirradiation poses a distinct therapeutic challenge owing to risks associated with exceeding normal tissue tolerances and possibly more therapeutically…”
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Gemcitabine-Induced Radiation Recall Myositis: Case Report and Review of the Literature
Published in Case reports in oncology (27-03-2018)“…Gemcitabine-induced radiation recall (GIRR) is a phenomenon wherein the administration of gemcitabine induces an inflammatory reaction within an area of prior…”
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Benign Adenomyoepithelioma: An Unrecognised Precursor of Ductal Carcinoma in Situ in Patient With Lynch Syndrome
Published in International journal of surgical pathology (01-10-2024)“…Currently, there is no robust evidence demonstrating a clear association between Lynch syndrome and non-malignant breast pathology such as adenomyoepithelioma…”
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Overcoming Immunotherapy Resistance With Radiation Therapy and Dual Immune Checkpoint Blockade
Published in Advances in radiation oncology (01-07-2022)Get full text
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Single and Multifraction Spine Stereotactic Body Radiation Therapy and the Risk of Radiation Induced Myelopathy
Published in Advances in radiation oncology (01-11-2022)“…This study reports on the risk of radiation-induced myelitis (RM) of the spinal cord from a large single-institutional experience with 1 to 5 fraction…”
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Outcomes and toxicities of stereotactic body radiation therapy for non-spine bone oligometastases
Published in Practical Radiation Oncology (01-03-2014)“…Stereotactic body radiation therapy (SBRT) is being applied more widely for oligometastatic disease. This technique is now being used for non-spine bony…”
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Feasibility of proton transmission-beam stereotactic ablative radiotherapy versus photon stereotactic ablative radiotherapy for lung tumors: a dosimetric and feasibility study
Published in PloS one (02-06-2014)“…Stereotactic ablative radiotherapy is being increasingly adopted in the treatment of lung tumors. The use of proton beam therapy can further reduce dose to…”
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