Search Results - "Park, Sangmi S."
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1
Type 1 diabetes contributes to combined pulmonary fibrosis and emphysema in male alpha 1 antitrypsin deficient mice
Published in PloS one (11-10-2023)“…Type 1 diabetes (T1D) is a metabolic disease characterized by hyperglycemia and can affect multiple organs, leading to life-threatening complications…”
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Extracellular glucose triggers metabolic reprogramming of cultured human bronchial epithelial cells and indirect fibroblast activation
Published in FEBS open bio (01-09-2024)“…Glucose is essential for energy metabolism, and its usage can determine other cellular functions, depending on the cell type. In some pathological conditions,…”
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Mechanisms Linking COPD to Type 1 and 2 Diabetes Mellitus: Is There a Relationship between Diabetes and COPD?
Published in Medicina (Kaunas, Lithuania) (01-08-2022)“…Chronic obstructive pulmonary disease (COPD) patients frequently suffer from multiple comorbidities, resulting in poor outcomes for these patients. Diabetes is…”
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4
LRP1 loss in airway epithelium exacerbates smoke-induced oxidative damage and airway remodeling
Published in Journal of lipid research (01-04-2022)“…The LDL receptor-related protein 1 (LRP1) partakes in metabolic and signaling events regulated in a tissue-specific manner. The function of LRP1 in airways has…”
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5
Therapeutic Potential of Alpha-1 Antitrypsin in Type 1 and Type 2 Diabetes Mellitus
Published in Medicina (Kaunas, Lithuania) (20-04-2021)“…Alpha-1 antitrypsin (AAT) has established anti-inflammatory and immunomodulatory effects in chronic obstructive pulmonary disease but there is increasing…”
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6
Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Emphysema
Published in American journal of respiratory cell and molecular biology (01-11-2023)“…The activity of PP2A (protein phosphatase 2A), a serine-threonine phosphatase, is reduced by chronic cigarette smoke (SM) exposure and α-1 antitrypsin (AAT)…”
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Small-Molecule Activation of Protein Phosphatase 2A Counters Bleomycin-Induced Fibrosis in Mice
Published in ACS pharmacology & translational science (10-11-2023)“…The activity of protein phosphatase 2A (PP2A), a serine-threonine phosphatase, is reduced in the lung fibroblasts of idiopathic pulmonary fibrosis (IPF)…”
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Standardization of the first Korean national reference standard for snake (Gloydius brevicaudus) antivenom
Published in Toxicological research (Seoul) (2020)“…In 2017, the second national reference standard (NRS) for Gloydius snake venom was established to replace the first NRS for Gloydius snake venom. In connection…”
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9
Clinical Characteristics of Infantile Colic
Published in Neonatal medicine (Seoul, Korea) (01-02-2019)“…Purpose: To diagnose infantile colic from parent questionnaires, as well as investigating the risk factors and clinical course of infantile colic. Methods: We…”
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A Collaborative Study to Establish the Second Korean National Reference Standard for Snake Venom
Published in Toxicological research (Seoul) (2018)“…In 2015, a candidate for the second national reference standard (NRS) of Gloydius snake venom was produced to replace the first NRS of Gloydius snake venom. In…”
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