Search Results - "Park, Sang S."

Broadband dependence of atmospheric transmissions in the UV and total solar radiation by Lee, Hana, Kim, Woogyung, Lee, Yun G., Koo, Ja-Ho, Jung, Yeonjin, Park, Sang S., Cho, Hi-Ku, Kim, Jhoon

“…Atmospheric broadband transmissions of clouds, aerosols, and ozone in the erythemally weighted ultraviolet (EUV, 290-320 nm), total (spectrally integrated)…”
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Cytochrome P450-related differences between rats and mice in the metabolism of benzene, toluene and trichloroethylene in liver microsomes by Nakajima, T, Wang, R S, Elovaara, E, Park, S S, Gelboin, H V, Vainio, H

“…In evaluating the risks to humans of exposure to chemicals, the results of studies in rodents are sometimes used as a basis for extrapolation. It is therefore…”
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A comparative study on the contribution of cytochrome P450 isozymes to metabolism of benzene, toluene and trichloroethylene in rat liver by Nakajima, T, Wang, R S, Elovaara, E, Park, S S, Gelboin, H V, Vainio, H

“…The contribution of P450IIE1, P450IIC11/6, P450IIB1/2 and P450IA1/2 to the formation of chloral hydrate (CH) from trichloroethylene (TRI) was investigated in…”
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Role of Cytochrome P450 Enzyme Induction in the Metabolic Activation of Benzo[c]phenanthrene in Human Cell Lines and Mouse Epidermis by Einolf, Heidi J, Story, William T, Marcus, Craig B, Larsen, Michele C, Jefcoate, Colin R, Greenlee, William F, Yagi, Haruhiko, Jerina, Donald M, Amin, Shantu, Park, Sang S, Gelboin, Harry V, Baird, William M

“…The environmental contaminant benzo[c]phenanthrene (B[c]Ph) has weak carcinogenic activity in rodent bioassays; however, the fjord region diol epoxides of…”
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Stabilization of cytochrome P450j messenger ribonucleic acid in the diabetic rat by Song, B J, Matsunaga, T, Hardwick, J P, Park, S S, Veech, R L, Yang, C S, Gelboin, H V, Gonzalez, F J

“…Cytochrome P450j, an enzyme involved in nitrosamine metabolism, is expressed in hepatic, pulmonary, and renal tissues and its level is elevated in ethanol- and…”
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Catalysis of the cysteine conjugation and protein binding of acetaminophen by microsomes from a human lymphoblast line transfected with the cDNAs of various forms of human cytochrome P450 by Zhou, L, Erickson, R R, Hardwick, J P, Park, S S, Wrighton, S A, Holtzman, J L

“…We have previously found that for acetaminophen kinetic differences exist between the hepatic microsomal catalyzed protein binding and cysteine conjugation. We…”
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EFFECTS OF MOTORCYCLE EXHAUST ON CYTOCHROME P-450-DEPENDENT MONOOXYGENASES AND GLUTATHIONE S-TRANSFERASE IN RAT TISSUES by Ueng, T H, Hwang, W P, Chen, R M, Wang, H W, Kuo, M L, Park, S S, Guengerich, F P

“…The effects of motorcycle exhaust (ME) on cytochrome P-450 (P-450) -dependent monooxygenases were determined using rats exposed to the exhaust by either…”
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Mechanism of induction of cytochrome P-450ac (P-450j) in chemically induced and spontaneously diabetic rats by Dong, Z G, Hong, J Y, Ma, Q A, Li, D C, Bullock, J, Gonzalez, F J, Park, S S, Gelboin, H V, Yang, C S

“…Previous studies demonstrated that a microsomal high-affinity N-nitrosodimethylamine demethylase activity and cytochrome P-450ac (an acetone/ethanol-inducible…”
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Monoclonal antibody-directed characterization of cytochrome P450 isozymes responsible for toluene metabolism in rat liver by Nakajima, T, Wang, R S, Elovaara, E, Park, S S, Gelboin, H V, Hietanen, E, Vainio, H

“…Monoclonal antibodies (MAbs) were used to study the contribution of cytochromes P450IA1/IA2, P450IIB1/IIB2, P450IIC11/IIC6 and P450IIE1 to toluene side-chain…”
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Monoclonal antibody-directed characterization of benzene, ethoxyresorufin and pentoxyresorufin metabolism in rat liver microsomes by Nakajima, T, Elovaara, E, Park, S S, Gelboin, H V, Hietanen, E, Vainio, H

“…The contribution of cytochrome P450IA, P450IIB, P450IICII and P450IIEI to the oxidative metabolism of benzene, 7-ethoxyresorufin and 7-pentoxyresorufin was…”
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Monoclonal antibodies to ethanol-induced rat liver cytochrome P-450 that metabolizes aniline and nitrosamines by IN-YOUNG KO, PARK, S. S, SONG, B. J, PATTEN, C, YOUNGZHUANG TAN, HAH, Y. C, YANG, C. S, GELBOIN, H. V

“…Hybridomas were prepared from mouse myeloma cells and spleen cells derived from female BALB/c mice that had been immunized with a partially purified…”
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Adipokines, insulin resistance, metabolic syndrome, and breast cancer recurrence: a cohort study by Oh, Sang Woo, Park, Cheol-Young, Lee, Eun Sook, Yoon, Yeong Sook, Lee, Eon Sook, Park, Sang Shin, Kim, Yuil, Sung, Nak Jin, Yun, Young Ho, Lee, Keun Seok, Kang, Han Sung, Kwon, Youngmee, Ro, Jungsil

“…Several in vitro studies have suggested the effects of adipokines and insulin resistance on breast cancer cell proliferation and survival. However, little is…”
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Specificity and cross-reactivity of monoclonal and polyclonal antibodies against cytochrome P-450E of the marine fish scup by Kloepper-Sams, P J, Park, S S, Gelboin, H V, Stegeman, J J

“…Monoclonal antibody (MAb) 1-12-3 generated against liver cytochrome P-450E (P-450E), an aryl hydrocarbon hydroxylase of the marine fish Stenotomus chrysops…”
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Ethanol Induces CYP2E1 by Protein Stabilization by Roberts, Ben J., Song, Byoung-Joon, Soh, Yunjo, Park, Sang S., Shoaf, Susan E.

“…In the present study, we demonstrate that ethanol induces CYP2E1 by protein stabilization in vivo. The control half-life of CYP2E1 was determined to be 6-7 h…”
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Monoclonal antibodies that inhibit enzyme activity of 3-methylcholanthrene-induced cytochrome P-450 by Park, S S, Fujino, T, West, D, Guengerich, F P, Gelboin, H V

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Induction of cytochrome P450-dependent monooxygenases in hamster tissues by fasting by Ueng, T H, Ueng, Y F, Chen, T L, Park, S S, Iwasaki, M, Guengerich, F P

“…The effects of fasting on liver, kidney, and lung monooxygenases were studied using hamsters starved for 4 days. Fasting treatment increased microsomal…”
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Immunochemical characterization of cytochrome P-450 isozymes responsible for benzene oxidation in the rat liver by Nakajima, T, Elovaara, E, Park, S S, Gelboin, H V, Hietanen, E, Vainio, H

“…The contribution of cytochrome P-450 isozymes to benzene metabolism in liver microsomes from fed, fasted, pyrazole-, phenobarbital (PB)- and ethanol-treated…”
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Immunochemical detection of cytochrome P450 isozymes induced in rat liver byn-hexane, 2-hexanone and acetonyl acetone by Nakajima, Tamie, Elovaara, Eivor, Park, Sang S., Gelboin, Harry V., Vainio, Harri

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Ethanol induces CYP2E1 by protein stabilization. Role of ubiquitin conjugation in the rapid degradation of CYP2E1 by Roberts, B J, Song, B J, Soh, Y, Park, S S, Shoaf, S E

“…In the present study, we demonstrate that ethanol induces CYP2E1 by protein stabilization in vivo. The control half-life of CYP2E1 was determined to be 6-7 h…”
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Monoclonal antibody-directed immunopurification and identification of cytochromes P-450 by Friedman, F K, Robinson, R C, Park, S S, Gelboin, H V

“…Several rat liver cytochromes P-450 have been substantially purified in a one-step immunoadsorption procedure using Sepharose-bound monoclonal antibodies…”
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