Search Results - "Park, Nok Hyun"
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nc886, a Non-Coding RNA, Is a New Biomarker and Epigenetic Mediator of Cellular Senescence in Fibroblasts
Published in International journal of molecular sciences (20-12-2021)“…Functional studies of organisms and human models have revealed that epigenetic changes can significantly impact the process of aging. Non-coding RNA (ncRNA),…”
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Inhibition effect of Gynura procumbens extract on UV-B-induced matrix-metalloproteinase expression in human dermal fibroblasts
Published in Journal of ethnopharmacology (01-09-2011)“…Gynura procumbens Merr. (Asteraceae) has been used as a traditional remedy for various skin diseases in certain areas of Southeast Asia. In order to evaluate…”
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3
Circadian Expression of TIMP3 Is Disrupted by UVB Irradiation and Recovered by Green Tea Extracts
Published in International journal of molecular sciences (16-02-2019)“…The human skin is the outermost physical barrier and has its own circadian machinery that works either cooperatively with the central clock, or autonomously…”
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4
Coumestrol Down-Regulates Melanin Production in Melan-a Murine Melanocytes through Degradation of Tyrosinase
Published in Biological & pharmaceutical bulletin (2017)“…Pigmentation reflects skin darkening caused by melanin production, but excessive melanin synthesis may cause problems, such as melasma, solar lentigo, dark…”
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Different effects of five depigmentary compounds, rhododendrol, raspberry ketone, monobenzone, rucinol and AP736 on melanogenesis and viability of human epidermal melanocytes
Published in Experimental dermatology (01-01-2016)“…Numerous medications are used to treat hyperpigmentation. However, several reports have indicated that repeated application of some agents, such as…”
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Activation of transient receptor potential melastatin 8 reduces ultraviolet B-induced prostaglandin E2 production in keratinocytes
Published in Journal of dermatology (01-11-2013)“…Transient receptor potential melastatin 8 (TRPM8) is a member of the TRP family, and is activated at temperatures below 22°C, or by cooling compounds such as…”
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Anti-inflammatory effect of green tea petiole extracts in poly(I:C)–stimulated human epidermal keratinocytes and a human 3D skin equivalent
Published in European journal of inflammation (01-06-2019)“…Green tea is one of the most popular non-alcoholic beverage crops worldwide. Leaf extracts of the green tea, Camellia sinensis, are known to have natural…”
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Comparative secretome analysis of human follicular dermal papilla cells and fibroblasts using shotgun proteomics
Published in BMB reports (01-04-2012)“…The dermal papilla cells (DPCs) of hair follicles are known to secrete paracrine factors for follicular cells. Shotgun proteomic analysis was performed to…”
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9
Metabolomics approach for understanding geographical dependence of soybean leaf metabolome
Published in Food research international (01-04-2018)“…The soybean plant (Glycine max) is widely used as an ingredient in various foods, nutraceuticals and cosmetics, due to their diverse bioactive compounds. Their…”
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Synthetic Retinoid Seletinoid G Improves Skin Barrier Function through Wound Healing and Collagen Realignment in Human Skin Equivalents
Published in International journal of molecular sciences (30-04-2020)“…The outer epidermal skin is a primary barrier that protects the body from extrinsic factors, such as ultraviolet (UV) radiation, chemicals and pollutants. The…”
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Theabrownin in Black Tea Suppresses UVB-induced Matrix Metalloproteinase-1 Expression in HaCaT Keratinocytes
Published in Biotechnology and bioprocess engineering (01-06-2022)“…Theabrownin is a heterogeneous polyphenolic compound, obtained from fermented dark teas, with many bioactive functions. However, the role of theabrownin in…”
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Antimelanogenic Efficacy of Melasolv (3,4,5-Trimethoxycinnamate Thymol Ester) in Melanocytes and Three-Dimensional Human Skin Equivalent
Published in Skin pharmacology and physiology (01-01-2017)“…Excessive melanogenesis often causes unaesthetic hyperpigmentation. In a previous report, our group introduced a newly synthesized depigmentary agent,…”
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13
Protective effects of amentoflavone on Lamin A-dependent UVB-induced nuclear aberration in normal human fibroblasts
Published in Bioorganic & medicinal chemistry letters (01-11-2011)“…Lamin A-dependent nuclear aberration and DNA damage was found in premature aging disease or normally old individuals. In this study, UVB irradiation was used…”
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Amentoflavone Inhibits UVB-Induced Matrix Metalloproteinase-1 Expression Through the Modulation of AP-1 Components in Normal Human Fibroblasts
Published in Applied biochemistry and biotechnology (01-03-2012)“…Amentoflavone is a well-known biflavonoid that has diverse biological effects. Previously, we reported that amentoflavone suppressed UVB-induced matrix…”
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All-trans retinoic acid prevents oxidative stress-mediated cellular senescence via upregulation of insulin-like growth factor binding protein-6 in normal human epidermal keratinocytes
Published in Archives of biological sciences (2021)“…All-trans retinoic acid (ATRA) influences cellular proliferation and differentiation but its mechanisms of action are not understood in keratinocytes. To…”
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Vectors designed for efficient molecular manipulation in Candida albicans
Published in Yeast (Chichester, England) (15-09-2002)“…Functional studies on genes of Candida albicans have been hampered by the fact that few vectors are available for efficient cloning and expression in C…”
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Comparative secretome analysis of human follicular dermal papilla cells and fibroblasts using shotgun proteomics
Published in BMB reports (30-04-2012)“…The dermal papilla cells (DPCs) of hair follicles are known to secrete paracrine factors for follicular cells. Shotgun proteomic analysis was performed to…”
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18
Alstonia scholaris R. Br. Significantly Inhibits Retinoid-Induced Skin Irritation In Vitro and In Vivo
Published in Evidence-based complementary and alternative medicine (01-01-2012)“…Topical retinoids inhibit matrix metalloproteinases and accelerate collagen synthesis, thereby triggering antiaging effects in the skin. However, topical…”
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Identification of sake extract as a new anti-melanogenic ingredient by in vitro and clinical trials
Published in Natural product communications (01-11-2013)“…Overproduction of melanin is the cause of skin hyperpigmentation, which is related to several skin diseases and cosmetic concerns. Sake is a Japanese alcoholic…”
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Interacting Domain Between Yeast Chitin Synthase 3 and Chitin Synthase 4 is Involved in Biogenesis of Chitin Ring, but not for Cell Wall Chitin
Published in Journal of microbiology and biotechnology (30-04-2003)“…Recently, we identified a domain, termed MIRC3-4, for the protein-protein interaction between yeast chitin synthase 3 (CHS3) and chitin synthase 4 (CHS4). In…”
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