Search Results - "Park, Lauren K"
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Skeletal Muscle Contractile Function in Heart Failure With Reduced Ejection Fraction-A Focus on Nitric Oxide
Published in Frontiers in physiology (01-06-2022)“…Despite advances over the past few decades, heart failure with reduced ejection fraction (HFrEF) remains not only a mortal but a disabling disease. Indeed, the…”
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The inorganic NItrate and eXercise performance in Heart Failure (iNIX-HF) phase II clinical trial: Rationale and study design
Published in Contemporary clinical trials communications (01-12-2023)“…Heart failure (HF) is a debilitating and often fatal disease that affects millions of people worldwide. Diminished nitric oxide synthesis, signaling, and…”
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Safety, tolerability, and effectiveness of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in combination with standard chemotherapy for patients with advanced, inoperable pancreatic adenocarcinoma: a phase 1b observational study
Published in Cancer & metabolism (18-05-2023)“…Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy. Thus, there is an urgent need for safe and effective novel therapies. PDAC's excessive reliance…”
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A prospective cohort study of the impact of outpatient Intensive Cardiac Rehabilitation on depression and cardiac self-efficacy
Published in American heart journal plus (01-01-2022)“…To evaluate whether an Intensive Cardiac Rehabilitation (ICR) program improves depression and cardiac self-efficacy among patients with a qualifying cardiac…”
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Links between ceramides and cardiac function
Published in Current opinion in lipidology (01-02-2022)“…Total ceramide levels in cardiac tissue relate to cardiac dysfunction in animal models. However, emerging evidence suggests that the fatty acyl chain length of…”
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Impact of sex and diet-induced weight loss on vascular insulin sensitivity in type 2 diabetes
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-03-2023)“…Vascular insulin resistance, a major characteristic of obesity and type 2 diabetes (T2D), manifests with blunting of insulin-induced vasodilation. Although…”
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Skeletal muscle microvascular insulin resistance in type 2 diabetes is not improved by eight weeks of regular walking
Published in Journal of applied physiology (1985) (01-08-2020)“…We aimed to examine whether individuals with type 2 diabetes (T2D) exhibit suppressed leg vascular conductance and skeletal muscle capillary perfusion in…”
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Prospective Study of the Impact of Outpatient Intensive Cardiac Rehabilitation on Diet Quality, Health-related Quality of Life, and Cardiovascular Health Indices
Published in The American journal of cardiology (01-04-2023)“…Intensive cardiac rehabilitation (ICR) programs are approved by the Centers for Medicare & Medicaid Services on the basis of their expected benefits for…”
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Persistent insulin signaling coupled with restricted PI3K activation causes insulin-induced vasoconstriction
Published in American journal of physiology. Heart and circulatory physiology (01-11-2019)“…Insulin modulates vasomotor tone through vasodilator and vasoconstrictor signaling pathways. The purpose of the present work was to determine whether…”
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Benefits of the First Pritikin Outpatient Intensive Cardiac Rehabilitation Program
Published in Journal of cardiopulmonary rehabilitation and prevention (01-11-2022)“…Intensive cardiac rehabilitation (ICR) is a comprehensive, medically supervised exercise treatment program covered by Medicare for patients with approved…”
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Chronic Elevation of Endothelin-1 Alone May Not Be Sufficient to Impair Endothelium-Dependent Relaxation
Published in Hypertension (Dallas, Tex. 1979) (01-12-2019)“…Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide considered to be causally implicated in hypertension and the development of cardiovascular disease…”
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Links between ceramides and cardiac function
Published in Current opinion in lipidology (09-12-2021)Get full text
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Abstract 13107: Effectiveness Of The Outpatient Pritikin Intensive Cardiac Rehabilitation Program In Patients With Heart Failure
Published in Circulation (New York, N.Y.) (16-11-2021)“…IntroductionThe Pritikin intensive cardiac rehabilitation (ICR) program includes structured exercise sessions augmented by heart health education sessions for…”
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