Search Results - "Park, Kyunghyuk"

Contribution of RdDM to the ecotype-specific differential methylation on conserved as well as highly variable regions between Arabidopsis ecotypes by Lee, Jaehoon, Shin, Sang-Yoon, Lee, Sang-Kyu, Park, Kyunghyuk, Gill, Haechan, Hyun, Youbong, Jeong, Choongwon, Jeon, Jong-Seong, Shin, Chanseok, Choi, Yeonhee

“…Several studies showed genome-wide DNA methylation during Arabidopsis embryogenesis and germination. Although it has been known that the change of DNA…”
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DEMETER-mediated DNA Demethylation in Gamete Companion Cells and the Endosperm, and its Possible Role in Embryo Development in Arabidopsis by Park, Kyunghyuk, Lee, Seunga, Yoo, Hyunjin, Choi, Yeonhee

“…Seed development begins upon double fertilization, producing the embryo and endosperm, which are genetically identical, except for their ploidy level. DEMETER…”
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Distinct regulatory pathways contribute to dynamic CHH methylation patterns in transposable elements throughout Arabidopsis embryogenesis by Lee, Jaehoon, Lee, Seunga, Park, Kyunghyuk, Shin, Sang-Yoon, Frost, Jennifer M, Hsieh, Ping-Hung, Shin, Chanseok, Fischer, Robert L, Hsieh, Tzung-Fu, Choi, Yeonhee

“…CHH methylation (mCHH) increases gradually during embryogenesis across dicotyledonous plants, indicating conserved mechanisms of targeting and conferral…”
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Multidimensional fragmentomic profiling of cell-free DNA released from patient-derived organoids by Kim, Jaeryuk, Hong, Seung-Pyo, Lee, Seyoon, Lee, Woochan, Lee, Dakyung, Kim, Rokhyun, Park, Young Jun, Moon, Sungji, Park, Kyunghyuk, Cha, Bukyoung, Kim, Jong-Il

“…BackgroundFragmentomics, the investigation of fragmentation patterns of cell-free DNA (cfDNA), has emerged as a promising strategy for the early detection of…”
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A single-cell atlas of in vitro multiculture systems uncovers the in vivo lineage trajectory and cell state in the human lung by Lee, Woochan, Lee, Seyoon, Yoon, Jung-Ki, Lee, Dakyung, Kim, Yuri, Han, Yeon Bi, Kim, Rokhyun, Moon, Sungji, Park, Young Jun, Park, Kyunghyuk, Cha, Bukyoung, Choi, Jaeyong, Kim, Juhyun, Ha, Na-young, Kim, Kwhanmien, Cho, Sukki, Cho, Nam-Hyuk, Desai, Tushar J., Chung, Jin-Haeng, Lee, Joo-Hyeon, Kim, Jong-Il

“…We present an in-depth single-cell atlas of in vitro multiculture systems on human primary airway epithelium derived from normal and diseased lungs of 27…”
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An Optimized Method for the Construction of a DNA Methylome from Small Quantities of Tissue or Purified DNA from Arabidopsis Embryo by Yoo, Hyunjin, Park, Kyunghyuk, Lee, Jaehoon, Lee, Seunga, Choi, Yeonhee

“…DNA methylation is an important epigenetic mechanism affecting genome structure, gene regulation, and the silencing of transposable elements. Cell- and…”
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Optimized Methods for the Isolation of Arabidopsis Female Central Cells and Their Nuclei by Park, Kyunghyuk, Frost, Jennifer M, Adair, Adam James, Kim, Dong Min, Yun, Hyein, Brooks, Janie S, Fischer, Robert L, Choi, Yeonhee

“…The female gametophyte contains seven cells with eight haploid nuclei buried within layers of sporophytic tissue. Following double fertilization, the egg and…”
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Experimental development of the epigenomic library construction method to elucidate the epigenetic diversity and causal relationship between epigenome and transcriptome at a single-cell level by Park, Kyunghyuk, Jeon, Min Chul, Kim, Bokyung, Cha, Bukyoung, Kim, Jong-Il

“…The method of single-cell RNA sequencing has been rapidly developed, and numerous experiments have been conducted over the past decade. Their results allow us…”
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Optimized Methods for the Isolation of Arabidopsis Female Central Cells and Their Nuclei by Park, Kyunghyuk, Frost, Jennifer M, Adair, Adam James, Kim, Dong Min, Yun, Hyein, Brooks, Janie S, Fischer, Robert L, Choi, Yeonhee

“…The Arabidopsis female gametophyte contains seven cells with eight haploid nuclei buried within layers of sporophytic tissue. Following double fertilization,…”
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DNA demethylation is initiated in the central cells of Arabidopsis and rice by Park, Kyunghyuk, Kim, M. Yvonne, Vickers, Martin, Park, Jin-Sup, Hyun, Youbong, Okamoto, Takashi, Zilberman, Daniel, Fischer, Robert L., Feng, Xiaoqi, Choi, Yeonhee, Scholten, Stefan

“…Cytosine methylation is a DNA modification with important regulatory functions in eukaryotes. In flowering plants, sexual reproduction is accompanied by…”
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Genetic and epigenetic alterations in aging and rejuvenation of human by Park, Kyunghyuk, Jeon, Min Chul, Lee, Dakyung, Kim, Jong-Il, Im, Sun-Wha

“…All the information essential for life is encoded within our genome and epigenome, which orchestrates diverse cellular states spatially and temporally. In…”
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The catalytic subunit of Arabidopsis DNA polymerase α ensures stable maintenance of histone modification by Hyun, Youbong, Yun, Hyein, Park, Kyunghyuk, Ohr, Hyonhwa, Lee, Okchan, Kim, Dong-Hwan, Sung, Sibum, Choi, Yeonhee

“…Mitotic inheritance of identical cellular memory is crucial for development in multicellular organisms. The cell type-specific epigenetic state should be…”
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Control of DEMETER DNA demethylase gene transcription in male and female gamete companion cells in Arabidopsis thaliana by Park, Jin-Sup, Frost, Jennifer M., Park, Kyunghyuk, Ohr, Hyonhwa, Park, Guen Tae, Kim, Seohyun, Eom, Hyunjoo, Lee, Ilha, Brooks, Janie S., Fischer, Robert L., Choi, Yeonhee

“…The DEMETER (DME) DNA glycosylase initiates active DNA demethylation via the base-excision repair pathway and is vital for reproduction in Arabidopsis…”
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Identifiation of novel effector regulatory T cells through simulaneous single cell epigenetic and transcriptomic profiling by Nam, Hyo Jeong, Kim, Yong-Hee, Lee, Woochan, Byun, Nari, Yoon, Jeong Heon, Kim, Yong Chan, Chung, Hyunwoo, Jeong, Soyoung, Joh, Christine, Kang, Sung-Jun, Park, Kyunghyuk, Cha, Bukyoung, Kim, Jong-Il, Park, Chung-Gyu, Kim, Hyun Je

“…Regulatory T cells (Tregs) harness a central role in peripheral immune tolerance. Since its discovery, there have been numerous efforts to dissect the role of…”
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Differentiating visceral sensory ganglion organoids from induced pluripotent stem cells by Ahn, Kyusik, Park, Hwee-Seon, Choi, Sieun, Lee, Hojeong, Choi, Hyunjung, Hong, Seok Beom, Han, Jihui, Han, Jong Won, Ahn, Jinchul, Song, Jaehoon, Park, Kyunghyuk, Cha, Bukyung, Kim, Minseop, Liu, Hui-Wen, Song, Hyeonggyu, Kim, Sang Jeong, Chung, Seok, Kim, Jong-Il, Mook-Jung, Inhee

“…The ability to generate visceral sensory neurons (VSN) from induced pluripotent stem (iPS) cells may help to gain insights into how the gut–nerve–brain axis is…”
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An Optimized Method for the Construction of a DNA Methylome from Small Quantities of Tissue or Purified DNA from Arabidopsis Embryo by Yoo, Hyunjin, Park, Kyunghyuk, Lee, Jaehoon, Lee, Seunga, Choi, Yeonhee

“…DNA methylation is an important epigenetic mechanism affecting genome structure, gene regulation, and the silencing of transposable elements. Cell- and…”
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Abstract 4254: Genetically engineered human lung organoid models for lung cancer evolution study by Moon, Sungji, Kim, Rokhyun, Lee, Dakyung, Park, Kyunghyuk, Lee, Woochan, Lee, Seyoon, Park, Young Jun, Kim, Jongil

“…Initial cellular events in a transitional period from normal to cancer cells, such as transcriptomic or epigenetic dynamics, are poorly understood. Observing…”
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Assembly of glioblastoma tumoroids and cerebral organoids: a 3D in vitro model for tumor cell invasion by Kim, Jieun, Kim, Rokhyun, Lee, Wonseok, Kim, Gyu Hyun, Jeon, Seeun, Lee, Yun Jin, Lee, Jong Seok, Kim, Kyung Hyun, Won, Jae-Kyung, Lee, Woochan, Park, Kyunghyuk, Kim, Hyun Je, Im, Sun-Wha, Lee, Kea Joo, Park, Chul-Kee, Kim, Jong-Il, Lee, Ji Yeoun

“…Glioblastoma (GBM) has a fatal prognosis because of its aggressive and invasive characteristics. Understanding the mechanism of invasion necessitates an…”
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Experimental development of the epigenomic library construction method to elucidate the epigenetic diversity and causal relationship between epigenome and transcriptome at a single-cell level by Park, Kyunghyuk, Jeon, Min Chul, Kim, Bokyung, Cha, Bukyoung, Kim, Jong-Il

“…The method of single-cell RNA sequencing has been rapidly developed, and numerous experiments have been conducted over the past decade. Their results allow us…”
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A whole-genome reference panel of 14,393 individuals for East Asian populations accelerates discovery of rare functional variants by Choi, Jaeyong, Kim, Sungjae, Kim, Juhyun, Son, Ho-Young, Yoo, Seong-Keun, Kim, Chang-Uk, Park, Young Jun, Moon, Sungji, Cha, Bukyoung, Jeon, Min Chul, Park, Kyunghyuk, Yun, Jae Moon, Cho, Belong, Kim, Namcheol, Kim, Changhoon, Kwon, Nak-Jung, Park, Young Joo, Matsuda, Fumihiko, Momozawa, Yukihide, Kubo, Michiaki, Kim, Hyun-Jin, Park, Jin-Ho, Seo, Jeong-Sun, Kim, Jong-Il, Im, Sun-Wha

“…Underrepresentation of non-European (EUR) populations hinders growth of global precision medicine. Resources such as imputation reference panels that match the…”
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