Search Results - "Park, Kyu Ho Paul"
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Identification of Leishmania donovani PEX5-PTS1 Interaction Inhibitors through Fluorescence Polarization-Based High-Throughput Screening
Published in Molecules (Basel, Switzerland) (17-04-2024)“…Leishmaniasis, an infectious disease caused by pathogenic parasites, affects millions of people in developing countries, and its re-emergence in developed…”
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Efficient long-term amplification of hepatitis B virus isolates after infection of slow proliferating HepG2-NTCP cells
Published in Journal of hepatology (01-08-2019)“…[Display omitted] •Cell culture system that mimicks complete HBV life cycle from entry to egress.•Efficient in vitro infection with crude HBV patient sera.•Up…”
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Mycobacterium tuberculosis Infection and Innate Responses in a New Model of Lung Alveolar Macrophages
Published in Frontiers in immunology (12-03-2018)“…Lung alveolar macrophages (AMs) are in the first line of immune defense against respiratory pathogens and play key roles in the pathogenesis of ( ) in humans…”
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Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro
Published in Frontiers in pharmacology (22-06-2023)“…The identification of chemical compounds that interfere with SARS-CoV-2 replication continues to be a priority in several academic and pharmaceutical…”
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Drug repurposing screening validated by experimental assays identifies two clinical drugs targeting SARS-CoV-2 main protease
Published in Frontiers in drug discovery (05-01-2023)“…The COVID-19 pandemic prompted several drug repositioning initiatives with the aim to rapidly deliver pharmacological candidates able to reduce SARS-CoV-2…”
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Identification of ILeishmania donovani/I PEX5-PTS1 Interaction Inhibitors through Fluorescence Polarization-Based High-Throughput Screening
Published in Molecules (Basel, Switzerland) (01-04-2024)“…Leishmaniasis, an infectious disease caused by pathogenic Leishmania parasites, affects millions of people in developing countries, and its re-emergence in…”
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Identification and characterization of new structural scaffolds modulating the activity of Mycobacterium tuberculosis dihydroneopterin aldolase (FolB) in vitro
Published in Frontiers in tropical diseases (01-06-2024)“…IntroductionAntifolates were among the first broad-spectrum compounds used as antimycobacterial agents and can still be of use when no other therapeutic…”
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