Search Results - "Park, Jong‐Wook"
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Inhibition of USP1 enhances anticancer drugs-induced cancer cell death through downregulation of survivin and miR-216a-5p-mediated upregulation of DR5
Published in Cell death & disease (24-09-2022)“…Ubiquitin-specific protease 1 (USP1) is a deubiquitinase involved in DNA damage repair by modulating the ubiquitination of major regulators, such as PCNA and…”
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Corosolic Acid Induces Non-Apoptotic Cell Death through Generation of Lipid Reactive Oxygen Species Production in Human Renal Carcinoma Caki Cells
Published in International journal of molecular sciences (27-04-2018)“…Corosolic acid is one of the pentacyclic triterpenoids isolated from and has been reported to exhibit anti-cancer and anti-proliferative activities in various…”
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3
Inhibition of USP2 Enhances TRAIL-Mediated Cancer Cell Death through Downregulation of Survivin
Published in International journal of molecular sciences (01-08-2023)“…Ubiquitin-specific protease 2 (USP2) is a deubiquitinase belonging to the USPs subfamily. USP2 has been known to display various biological effects including…”
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Altered mRNA expression levels of the major components of sphingolipid metabolism, ceramide synthases and their clinical implication in colorectal cancer
Published in Oncology reports (01-12-2018)“…Ceramide synthases (CerSs) synthesize various ceramides of different acyl chain lengths and serve important roles in the proliferation and death of cancer…”
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Microstructural and interface geometrical influence on the mechanical fatigue property of aluminum/high-strength steel lap joints using resistance element welding for lightweight vehicles: experimental and computational investigation
Published in Journal of materials research and technology (01-03-2022)“…The present study investigates a fatigue property and its microstructural and interface geometrical effect on the resistance element welded (REWed) aluminum…”
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Melatonin sensitizes Caki renal cancer cells to kahweol-induced apoptosis through CHOP-mediated up-regulation of PUMA
Published in Journal of pineal research (01-05-2011)“…: Melatonin has recently gained attention as a regulator of biologic processes in addition to its effects on circadian rhythms. The mechanisms whereby…”
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Axl Inhibitor R428 Enhances TRAIL-Mediated Apoptosis Through Downregulation of c-FLIP and Survivin Expression in Renal Carcinoma
Published in International journal of molecular sciences (02-07-2019)“…R428, a selective small molecule Axl inhibitor, is known to have anti-cancer effects, such as inhibition of invasion and proliferation and induction of cell…”
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Sanguinarine-induced apoptosis: Generation of ROS, down-regulation of Bcl-2, c-FLIP, and synergy with TRAIL
Published in Journal of cellular biochemistry (01-06-2008)“…Sanguinarine is a benzophenanthridine alkaloid derived from the root of Sanguinaria canadensis and other poppy‐fumaria species, possessing potent…”
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9
RU486 Induces Pro-Apoptotic Endoplasmic Reticulum Stress Through the Induction of CHOP Expression by Enhancing C/EBPδ Expression in Human Renal Carcinoma Caki Cells
Published in Journal of cellular biochemistry (01-02-2016)“…ABSTRACT RU486 (Mifepristone) is known as an antagonist of the progesterone receptor and glucocorticoid receptor. Here, we investigated the mechanism…”
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Galangin sensitizes TRAIL-induced apoptosis through down-regulation of anti-apoptotic proteins in renal carcinoma Caki cells
Published in Scientific reports (04-01-2016)“…Galangin, bioflavonoids, has been shown anti-cancer properties in various cancer cells. In this study, we investigated whether galangin could enhance…”
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Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5)
Published in Carcinogenesis (New York) (01-11-2005)“…Curcumin exhibits anti-inflammatory and antitumor activities. Although its functional mechanism has not been elucidated so far, numerous studies have shown…”
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12
Maritoclax Enhances TRAIL-Induced Apoptosis via CHOP-Mediated Upregulation of DR5 and miR-708-Mediated Downregulation of cFLIP
Published in Molecules (Basel, Switzerland) (20-11-2018)“…Maritoclax, an active constituent isolated from marine bacteria, has been known to induce Mcl-1 downregulation through proteasomal degradation. In this study,…”
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Garcinol Enhances TRAIL-Induced Apoptotic Cell Death through Up-Regulation of DR5 and Down-Regulation of c-FLIP Expression
Published in Molecules (Basel, Switzerland) (02-07-2018)“…Garcinol is a polyisoprenylated benzophenone derived from the fruit that possess potential therapeutic effects such as inhibition of inflammation and tumor…”
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14
Osthole enhances TRAIL-mediated apoptosis through downregulation of c-FLIP expression in renal carcinoma Caki cells
Published in Oncology reports (01-04-2017)“…Osthole, an active constituent isolated from the fruit of Cnidium monnieri (L.) Cusson, has been shown to induce various beneficial biochemical effects such as…”
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Synthesis, Photophysical, and Electroluminescent Device Properties of Zn(II)‐Chelated Complexes Based on Functionalized Benzothiazole Derivatives
Published in Advanced functional materials (22-05-2009)“…New Zn(II)‐chelated complexes based on benzothiazole derivatives, including substituted functional groups such as methyl (MeZn), methoxy (MeOZn), or fluorenyl…”
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The Origin of the Improved Efficiency and Stability of Triphenylamine‐Substituted Anthracene Derivatives for OLEDs: A Theoretical Investigation
Published in Chemphyschem (01-12-2008)“…Herein, we describe the molecular electronic structure, optical, and charge‐transport properties of anthracene derivatives computationally using density…”
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Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP
Published in Free radical biology & medicine (15-06-2009)“…Withaferin A (Wit A) has reportedly shown cytotoxicity in a variety of tumor cell lines. Here, we show that cotreatment with subtoxic doses of Wit A and tumor…”
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Doxycycline inhibits matrix metalloproteinase-9 and laminin degradation after transient global cerebral ischemia
Published in Neurobiology of disease (01-05-2009)“…Abstract Doxycycline, a tetracycline antibiotic inhibits matrix metalloproteinase (MMP) and reduces neuronal damage in focal brain ischemia. This study was…”
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Induction of apoptosis by withaferin A in human leukemia U937 cells through down-regulation of Akt phosphorylation
Published in Apoptosis (London) (01-12-2008)“…Withaferin A, a major chemical constituent of Withania somnifera, has been reported for its tumor cell growth inhibitory activity, antitumor effects, and…”
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Dual-Loop Two-Step ZQ Calibration for Dynamic Voltage-Frequency Scaling in LPDDR4 SDRAM
Published in IEEE journal of solid-state circuits (01-10-2018)“…This paper presents a dual-loop two-step ZQ calibration scheme with a 20-nm DRAM process to support dedicated supply voltages (V DD and V DDQ ). The proposed…”
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