Search Results - "Park, Joha"

Role of the small subunit processome in the maintenance of pluripotent stem cells by You, Kwon Tae, Park, Joha, Kim, V Narry

“…RNA-binding proteins (RBPs) play integral roles in gene regulation, yet only a small fraction of RBPs has been studied in the context of stem cells. Here we…”
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Functional Anatomy of the Human Microprocessor by Nguyen, Tuan Anh, Jo, Myung Hyun, Choi, Yeon-Gil, Park, Joha, Kwon, S. Chul, Hohng, Sungchul, Kim, V. Narry, Woo, Jae-Sung

“…MicroRNA (miRNA) maturation is initiated by Microprocessor composed of RNase III DROSHA and its cofactor DGCR8, whose fidelity is critical for generation of…”
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TALEN-based knockout library for human microRNAs by Kim, Young-Kook, Wee, Gabbine, Park, Joha, Kim, Jongkyu, Baek, Daehyun, Kim, Jin-Soo, Kim, V Narry

“…A transcription activator–like effector nuclease (TALEN)-mediated knockout approach to delete human microRNA (miRNA) genes was used to generate a library of…”
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Epitope-preserving magnified analysis of proteome (eMAP) by Park, Joha, Khan, Sarim, Yun, Dae Hee, Ku, Taeyun, Villa, Katherine L, Lee, Jiachen E, Zhang, Qiangge, Park, Juhyuk, Feng, Guoping, Nedivi, Elly, Chung, Kwanghun

“…Synthetic tissue-hydrogel methods have enabled superresolution investigation of biological systems using diffraction-limited microscopy. However, chemical…”
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PABP Cooperates with the CCR4-NOT Complex to Promote mRNA Deadenylation and Block Precocious Decay by Yi, Hyerim, Park, Joha, Ha, Minju, Lim, Jaechul, Chang, Hyeshik, Kim, V. Narry

“…Multiple deadenylases are known in vertebrates, the PAN2-PAN3 (PAN2/3) and CCR4-NOT (CNOT) complexes, and PARN, yet their differential functions remain…”
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PKR Senses Nuclear and Mitochondrial Signals by Interacting with Endogenous Double-Stranded RNAs by Kim, Yoosik, Park, Joha, Kim, Sujin, Kim, MinA, Kang, Myeong-Gyun, Kwak, Chulhwan, Kang, Minjeong, Kim, Baekgyu, Rhee, Hyun-Woo, Kim, V. Narry

“…Protein kinase RNA-activated (PKR) induces immune response by sensing viral double-stranded RNAs (dsRNAs). However, growing evidence suggests that PKR can also…”
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Short poly(A) tails are protected from deadenylation by the LARP1–PABP complex by Park, Joha, Kim, Myeonghwan, Yi, Hyerim, Baeg, Kyungmin, Choi, Yongkuk, Lee, Young-suk, Lim, Jaechul, Kim, V. Narry

“…Deadenylation generally constitutes the first and pivotal step in eukaryotic messenger RNA decay. Despite its importance in posttranscriptional regulations,…”
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Microprocessor depends on hemin to recognize the apical loop of primary microRNA by Nguyen, Tuan Anh, Park, Joha, Dang, Thi Lieu, Choi, Yeon-Gil, Kim, V Narry

“…Abstract Microprocessor, which consists of a ribonuclease III DROSHA and its cofactor DGCR8, initiates microRNA (miRNA) maturation by cleaving primary miRNA…”
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TALEN-based knockout library for human micro RNAs by Kim, Young-Kook, Wee, Gabbine, Park, Joha, Kim, Jongkyu, Baek, Daehyun, Kim, Jin-Soo, Kim, V. Narry

“…Various technical tools have been developed to probe the functions of microRNAs (miRNAs), yet their application has been limited by low efficacy and…”
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