Search Results - "Park, Jeong Sook"
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Enhancing the solubility and bioavailability of poorly water-soluble drugs using supercritical antisolvent (SAS) process
Published in International journal of pharmaceutics (01-03-2018)“…[Display omitted] Poor water solubility and poor bioavailability are problems with many pharmaceuticals. Increasing surface area by micronization is an…”
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Recent trends of self-emulsifying drug delivery system for enhancing the oral bioavailability of poorly water-soluble drugs
Published in Journal of pharmaceutical investigation (01-07-2021)“…Background The oral route is the most popular route for the clinical administration of drugs to treat various diseases. Before a drug is absorbed into the…”
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Gold nanorod‐photosensitizer conjugates with glutathione‐sensitive linkages for synergistic cancer photodynamic/photothermal therapy
Published in Biotechnology and bioengineering (01-05-2018)“…Recently, photodynamic therapy (PDT) has been intensively investigated as a useful modality for the treatment of various cancers. In addition, near infrared…”
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Overview of the Manufacturing Methods of Solid Dispersion Technology for Improving the Solubility of Poorly Water-Soluble Drugs and Application to Anticancer Drugs
Published in Pharmaceutics (19-03-2019)“…Approximately 40% of new chemical entities (NCEs), including anticancer drugs, have been reported as poorly water-soluble compounds. Anticancer drugs are…”
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Recent advances of nanotechnology for the delivery of anticancer drugs for breast cancer treatment
Published in Journal of pharmaceutical investigation (01-05-2020)“…Background Breast cancer is one of the most common causes of death for women worldwide. While chemotherapy is the treatment option for most cancers, surgery,…”
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Community-Based Oncology Nursing: Status and Prospects
Published in Asian oncology nursing (2022)Get full text
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Biomineralized hyaluronic acid/poly(vinylphosphonic acid) hydrogel for bone tissue regeneration
Published in Journal of applied polymer science (05-12-2014)“…ABSTRACT Novel biomineralized hydrogels composed of hyaluronic acid (HA) and vinyl phosphonic acid (VPAc) were designed with the aim of developing a biomimetic…”
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The use of PEGylated liposomes to prolong circulation lifetimes of tissue plasminogen activator
Published in Biomaterials (01-10-2009)“…Abstract Tissue plasminogen activator (tPA), a widely used thrombolytic agent, has an application limit due to short half-life. To prolong the half-life of…”
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Thermosensitive and mucoadhesive sol-gel composites of paclitaxel/dimethyl-β-cyclodextrin for buccal delivery
Published in PloS one (02-10-2014)“…The purpose of this study was to develop a buccal paclitaxel delivery system using the thermosensitive polymer Pluronic F127 (PF127) and the mucoadhesive…”
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Potential and Applications of Nanocarriers for Efficient Delivery of Biopharmaceuticals
Published in Pharmaceutics (06-12-2020)“…During the past two decades, the clinical use of biopharmaceutical products has markedly increased because of their obvious advantages over conventional…”
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Sustained delivery of triamcinolone acetonide from a thermosensitive microemulsion gel system for the treatment of sensorineural hearing loss
Published in Drug delivery (01-12-2023)“…Intratympanic administration for the delivery of steroids has been extensively studied but limited because of low permeability of the drug through the row…”
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High payload itraconazole‐incorporated lipid nanoparticles with modulated release property for oral and parenteral administration
Published in Journal of pharmacy and pharmacology (01-08-2017)“…Objectives The aim of this study was to develop high payload itraconazole‐incorporated lipid nanoparticles (HINP) with modulated release property using a…”
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Development of a binary lipid nanoparticles formulation of itraconazole for parenteral administration and controlled release
Published in International journal of pharmaceutics (04-01-2010)“…The principal aim of this study was to develop an intravenous formulation of itraconazole (ITZ) using lipid nanoparticles based on binary mixture of liquid and…”
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Design of novel proliposome formulation for antioxidant peptide, glutathione with enhanced oral bioavailability and stability
Published in Drug delivery (01-01-2019)“…To develop proliposome formulations to improve the oral bioavailability of l-glutathione (GSH), GSH-loaded proliposomes were prepared using the granule method…”
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Local drug delivery using poly(lactic-co-glycolic acid) nanoparticles in thermosensitive gels for inner ear disease treatment
Published in Drug delivery (01-01-2021)“…Intratympanic (IT) therapies have been explored to address several side effects that could be caused by systemic administration of steroids to treat inner ear…”
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Application of supercritical fluid technology for solid dispersion to enhance solubility and bioavailability of poorly water-soluble drugs
Published in International journal of pharmaceutics (15-12-2021)“…[Display omitted] Many new chemical entities (NCEs) have been discovered with the development of the pharmaceutical industry. However, the main disadvantage of…”
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Improved physicochemical characteristics of felodipine solid dispersion particles by supercritical anti-solvent precipitation process
Published in International journal of pharmaceutics (14-09-2005)“…Solid dispersions of felodipine were formulated with HPMC and surfactants by the conventional solvent evaporation (CSE) and supercritical anti-solvent…”
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Retained topical delivery of 5-aminolevulinic acid using cationic ultradeformable liposomes for photodynamic therapy
Published in European journal of pharmaceutical sciences (18-09-2011)“…5-Aminolevulinic acid (5-ALA), inducing photodynamic protoporphyrin (PpIX), is a hydrophilic molecule, resulting in leashing the capacity to cross tissue…”
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Optimization of Polyarginine-Conjugated PEG Lipid Grafted Proliposome Formulation for Enhanced Cellular Association of a Protein Drug
Published in Pharmaceutics (11-06-2019)“…The purpose of this study was to develop an oral proliposomal powder of protein using poly-l-arginine-conjugated…”
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