Search Results - "Park, Jason Y."
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Mass Spectrometry for COVID-19
Published in Clinical chemistry (Baltimore, Md.) (01-11-2020)“…In the United States, response to the COVID-19 coronavirus pandemic has been hampered by inadequate testing resources for the causative virus SARS-CoV-2. In…”
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Trends in the US and Canadian Pathologist Workforces From 2007 to 2017
Published in JAMA network open (03-05-2019)“…The current state of the US pathologist workforce is uncertain, with deficits forecast over the next 2 decades. To examine the trends in the US pathology…”
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Laboratory Action Plan for Emerging SARS-CoV-2 Variants
Published in Clinical chemistry (Baltimore, Md.) (01-05-2021)Get full text
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JAK-STAT6 Pathway Inhibitors Block Eotaxin-3 Secretion by Epithelial Cells and Fibroblasts from Esophageal Eosinophilia Patients: Promising Agents to Improve Inflammation and Prevent Fibrosis in EoE
Published in PloS one (16-06-2016)“…Although most studies on treatments for eosinophilic esophagitis (EoE) have focused on effects in the epithelium, EoE is a transmural disease. Eosinophils that…”
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Review of autoimmune metaplastic atrophic gastritis
Published in Gastrointestinal endoscopy (01-02-2013)Get full text
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Prospects for the commercialization of chemiluminescence-based point-of-care and on-site testing devices
Published in Analytical and bioanalytical chemistry (01-09-2014)“…Chemiluminescent reactions have found application in a number of commercial point-of-care and on-site testing devices. Notable examples include allergy tests…”
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Molecular signatures of pancreatic cancer
Published in Archives of pathology & laboratory medicine (1976) (01-06-2011)“…The introduction of genome- and epigenome-wide screening techniques has dramatically improved our understanding of the molecular mechanisms underlying the…”
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Helicobacter pylori Clarithromycin Resistance and Treatment Failure Are Common in the USA
Published in Digestive diseases and sciences (01-08-2016)“…Background Helicobacter pylori antibiotic resistance leads to frequent treatment failure. However, the current US prevalence of H. pylori clarithromycin…”
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Maximum dose, safety, tolerability and ketonemia after triheptanoin in glucose transporter type 1 deficiency (G1D)
Published in Scientific reports (01-03-2023)“…Augmentation of anaplerosis, or replenishment of carbon lost during intermediary metabolic transitions, is desirable in energy metabolism defects…”
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Cytoplasmic RNA quality control failure engages mTORC1-mediated autoinflammatory disease
Published in The Journal of clinical investigation (18-01-2022)“…Inborn errors of nucleic acid metabolism often cause aberrant activation of nucleic acid sensing pathways, leading to autoimmune or autoinflammatory diseases…”
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Combination of triheptanoin with the ketogenic diet in Glucose transporter type 1 deficiency (G1D)
Published in Scientific reports (02-06-2023)“…Fuel influx and metabolism replenish carbon lost during normal neural activity. Ketogenic diets studied in epilepsy, dementia and other disorders do not…”
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Mycophenolic Acid (Cellcept and Myofortic) Induced Injury of the Upper GI Tract
Published in The American journal of surgical pathology (01-09-2009)“…Mycophenolic acid (MPA) is an immunosuppressant drug commonly used in patients undergoing solid organ transplant. Although its pattern of inducing injury in…”
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Distinct autoantibody profiles across checkpoint inhibitor types and toxicities
Published in Oncoimmunology (2024)“…Immune checkpoint inhibitors (ICI) are increasingly used in combination. To understand the effects of different ICI categories, we characterized changes in…”
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Proton pump inhibitors decrease eotaxin-3 expression in the proximal esophagus of children with esophageal eosinophilia
Published in PloS one (02-07-2014)“…Besides reducing gastric acid secretion, proton pump inhibitors (PPIs) suppress Th2-cytokine-stimulated expression of an eosinophil chemoattractant (eotaxin-3)…”
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Cachexia, chorea, and pain in chronic nonbacterial osteitis and inflammatory bowel disease: a case report
Published in Journal of medical case reports (31-05-2023)“…Inflammatory bowel disease is an inflammatory disorder that primarily impacts the gastrointestinal tract, leading to malnutrition and chronic microscopic…”
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A Biopython-based method for comprehensively searching for eponyms in Pubmed
Published in MethodsX (01-01-2021)“…Eponyms are common in medicine; however, their usage has varied between specialties and over time. A search of specific eponyms will reveal the frequency of…”
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SCGN deficiency results in colitis susceptibility
Published in eLife (30-10-2019)“…Inflammatory bowel disease (IBD) affects 1.5-3.0 million people in the United States. IBD is genetically determined and many common risk alleles have been…”
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Association between body mass index, dosing strategy, and efficacy of immune checkpoint inhibitors
Published in Journal for immunotherapy of cancer (01-06-2021)“…BackgroundIncreased body mass index (BMI) has been associated with improved response to immune checkpoint inhibitors (ICIs) in multiple cancer types. We…”
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T-cell tolerant fraction as a predictor of immune-related adverse events
Published in Journal for immunotherapy of cancer (01-08-2023)“…Immune checkpoint inhibitor (ICI) therapies may cause unpredictable and potentially severe autoimmune toxicities termed immune-related adverse events (irAEs)…”
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Novel Helicobacter pylori Sequencing Test Identifies High Rate of Clarithromycin Resistance
Published in Journal of pediatric gastroenterology and nutrition (01-07-2014)“…ABSTRACT Objectives: Eradication therapy selection for Helicobacter pylori gastritis requires knowledge of the local resistance rate to clarithromycin. There…”
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