Search Results - "Park, James Hugh"

The association between preoperative CEA, the systemic inflammatory response and survival in colon cancer by Golder, Allan Matthew, Park, James Hugh, Mansouri, David, Horgan, Paul G., McMillan, Donald C., Roxburgh, Campbell SD

“…Abstract only 27 Background: Prior to curative surgery for colon cancer, carcinoembryonic antigen (CEA) has been reported to be a poor prognostic factor…”
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An investigation of the relationship between tumor location and survival following colon cancer resection by Knight, Katrina, Horgan, Paul G., McMillan, Donald C., Park, James Hugh, Roxburgh, Campbell SD

“…Abstract only 255 Background: Both tumour location and systemic inflammation (SI) have been related to survival in patients undergoing curative surgery for…”
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The potential for combined measures of the systemic inflammatory response (SIR) in colon cancer: An analysis of 2,300 patients by Golder, Allan Matthew, McMillan, Donald C., Mansouri, David, Park, James Hugh, Roxburgh, Campbell SD, Horgan, Paul G.

“…Abstract only 233 Background: The preoperative SIR clearly demonstrates independent prognostic significance following curative resection for colon cancer,…”
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The relationship between aortoiliac calcification and long-term outcome in rectal cancer resection by Knight, Katrina, Boland, Kate, McMillan, Donald C, Horgan, Paul G., Roxburgh, Campbell SD, Park, James Hugh

“…Abstract only 705 Background: The interaction between host and tumour factors is an important determinant of long-term outcome following rectal cancer…”
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Systemic inflammation, adjuvant chemotherapy, and survival in stage III colorectal cancer: Results from the ScotScan Colorectal Cancer Collaborative by Park, James Hugh, Fuglestad, Anniken Jorlo, Kostner, Anne Helene, Oliwa, Agata, Roxburgh, Campbell SD, Horgan, Paul G., Graham, Janet Shirley, Kersten, Christian, McMillan, Donald C.

“…Abstract only 228 Background: The systemic inflammatory response (SIR) is a poor prognostic marker in patients with colorectal cancer (CRC), and predicts poor…”
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Tumour infiltrating lymphocyte expression of PD-1 as a favourable prognostic factor in patients with mismatch repair competent colorectal cancer by Park, James Hugh, Grant, Lauren, Quinn, Jean A, Roxburgh, Campbell SD, McMillan, Donald C, Edwards, Joanne

“…Abstract only 631 Background: Immune checkpoint activation is recognised in mismatch repair (MMR) deficient colorectal cancer (CRC), and Programmed Cell Death…”
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The prognostic value of systemic inflammation in patients undergoing surgery for rectal cancer: Comparison of composite ratios and cumulative scores by Dolan, Ross, McSorley, Stephen Thomas, Park, James Hugh, Roxburgh, Campbell SD, Horgan, Paul G., McMillan, Donald C

“…Abstract only 579 Background: Colorectal cancer is the second commonest cause of cancer death in Europe and North America with rectal cancer making up a third…”
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Comorbidity and systemic inflammation are independent prognostic factors in patients with colorectal cancer: A ScotScan collaborative study by Park, James Hugh, Fuglestad, Anniken, Kostner, Anne Helene, Roseweir, Antonia K., Edwards, Joanne, Roxburgh, Campbell SD, Horgan, Paul G., Kersten, Christian, McMillan, Donald C

“…Abstract only 707 Background: Although inextricably linked, both comorbidity and systemic inflammatory responses have been shown to determine survival in…”
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Validation of the Glasgow Microenvironment Score in patients with colon cancer: A pathology-based prognostic tool by Alexander, Peter G, Roseweir, Antonia K., Pennel, Kathryn AF, Van Wyk, Hester Catharina, Powell, Arfon GMT, Roxburgh, Campbell SD, Horgan, Paul G., Edwards, Joanne, McMillan, Donald C., Park, James Hugh

“…Abstract only 206 Background: The Glasgow Microenvironment Score (GMS), comprised of assessment of the tumour inflammatory cell infiltrate (using…”
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Local immune response in colon cancer: Indicative of good or poor prognosis? by Alexander, Peter G, In, Jitwadee AF, Roseweir, Antonia K., Powell, Arfon GMT, Edwards, Joanne, Roxburgh, Campbell SD, Horgan, Paul G., McMillan, Donald C., Park, James Hugh

“…Abstract only 213 Background: The tumour microenvironment is an important determinant of survival in patients with colon cancer. Although the generalised…”
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Tumor site, clinicopathological characteristics, and survival of patients undergoing primary elective colorectal cancer resection by Park, James Hugh, Edwards, Joanne, Roxburgh, Campbell S.D., Mcmillan, Donald C., Horgan, Paul G.

“…Abstract only 585 Background: Cancers arising in the proximal and distal colorectum differ in embryological origin, predisposing genetic and epigenetic…”
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Does pre-operative aspirin and statin prescription modulate the post-operative systemic inflammatory response following surgery for colorectal cancer? by Watt, David G., Park, James Hugh, Ng, Shoukee K, Horgan, Paul G., McMillan, Donald C

“…Abstract only 596 Background: Aspirin use has been reported to reduce the pre-op systemic inflammatory response (SIR) in patients with colorectal cancer (CRC)…”
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Post-operative C-reactive protein concentration: A potential therapeutic target following surgery for colorectal cancer? by Watt, David G., Park, James Hugh, McSorley, Stephen Thomas, Horgan, Paul G., McMillan, Donald C

“…Abstract only 597 Background: Post-operative C-reactive protein concentrations (CRP) have been reported to be associated with the development of complications…”
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Signal transduction and activator of transcription 3 (STAT3), host inflammatory responses and survival of patients with colorectal cancer by Park, James Hugh, Mcmillan, Donald C., Clark, Jennifer, Horgan, Paul G., Roxburgh, Campbell S.D., Edwards, Joanne

“…Abstract only 606 Background: In patients with colorectal cancer (CRC), the local and systemic inflammatory responses (LIR and SIR) are important determinants…”
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The relationship between tumor location, tumor microenvironment, systemic inflammation, and cancer-specific survival in patients undergoing surgery for colon cancer by Patel, Meera, Park, James Hugh, van Wyk, Hester Catharina, Edwards, Joanne, Horgan, Paul G., McMillan, Donald C

“…Abstract only 689 Background: Evidence from clinical trials and cohort studies suggest primary tumour location is a prognostic factor in patients with advanced…”
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Evaluation of systemic inflammation based prognostic scores in patients with advanced oesophageal cancer receiving palliative radiotherapy by Dolan, Ross, Tilling, Elliot, Kong, Chia Y, MacLeod, Nicholas James, McSorley, Stephen Thomas, Park, James Hugh, Glen, Paul, Horgan, Paul G., Laird, Barry, McMillan, Donald C

“…Abstract only 21 Background: The presence of a systemic inflammatory response (SIR) in patients with advanced cancer is an increasingly recognised prognostic…”
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Phenotypic subtypes and risk of local recurrence after radical resection for rectal cancer by Knight, Katrina, Roseweir, Antonia K., Park, James Hugh, Edwards, Joanne, McMillan, Donald C, Horgan, Paul G., Roxburgh, Campbell SD

“…Abstract only 637 Background: Phenotypic subtypes for CRC are reported to stratify outcomes. The four subtypes are based on features within the consensus…”
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Phenotypic subtypes as a novel validated prognostic classification system for patients with colorectal cancer by Roseweir, Antonia K., Park, James Hugh, ten Hoorn, Sanne, Powell, Arfon GMT, Roxburgh, Campbell SD, McMillan, Donald C, Horgan, Paul G., Vermeulen, Louis, Edwards, Joanne

“…Abstract only 625 Background: There has been enormous effort to develop a prognostic genomic classification of colorectal cancer (CRC). As a result, mismatch…”
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Prognostic phenotypic subtypes to predict recurrence and response to adjuvant chemotherapy for colorectal cancer by Roseweir, Antonia K., Park, James Hugh, ten Hoorn, Sanne, Powell, Arfon GMT, Aherne, Susan, Roxburgh, Campbell SD, McMillan, Donald C., Horgan, Paul G., Ryan, Elizabeth, Sheahan, Keiran, Vermeulen, Louis, Paul, James, Graham, Janet Shirley, Sansom, Owen, Church, David, Iveson, Timothy, Edwards, Joanne

“…Abstract only 205 Background: Histological phenotypic subtypes have been proposed that stratify survival in a discovery cohort of patients with stage I-III…”
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Assessment of the tumor inflammatory cell infiltrate in preoperative colonoscopic biopsies of patients with primary operable colorectal cancer by Park, James Hugh, Mansouri, David, Orange, Clare, Horgan, Paul G., Mcmillan, Donald C., Roxburgh, Campbell S.D.

“…Abstract only 637 Background: The tumor inflammatory cell infiltrate is an important and potentially modifiable determinant of outcome in colorectal cancer…”
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